Understanding the Molecular Mechanisms of Polyphenol Inhibition of Amyloid β Aggregation
出版年份 2023 全文链接
标题
Understanding the Molecular Mechanisms of Polyphenol Inhibition of Amyloid β Aggregation
作者
关键词
-
出版物
ACS Chemical Neuroscience
Volume -, Issue -, Pages -
出版商
American Chemical Society (ACS)
发表日期
2023-10-28
DOI
10.1021/acschemneuro.3c00586
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer’s disease from bench to bedside
- (2022) Fahadul Islam et al. MOLECULAR NEUROBIOLOGY
- Insights into Molecular Mechanisms of EGCG and Apigenin on Disrupting Amyloid-Beta Protofibrils Based on Molecular Dynamics Simulations
- (2022) Mei Fang et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Serotonin and Melatonin Show Different Modes of Action on Aβ42 Protofibril Destabilization
- (2021) Yehong Gong et al. ACS Chemical Neuroscience
- Natural Products Targeting Amyloid Beta in Alzheimer’s Disease
- (2021) Joo-Hee Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Green Tea Extracts EGCG and EGC Display Distinct Mechanisms in Disrupting Aβ42 Protofibril
- (2020) Chendi Zhan et al. ACS Chemical Neuroscience
- Aβ(1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage
- (2020) Sonia Ciudad et al. Nature Communications
- Prevalence, risk factors, and management of dementia and mild cognitive impairment in adults aged 60 years or older in China: a cross-sectional study
- (2020) Longfei Jia et al. Lancet Public Health
- Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms
- (2019) Suman De et al. Nature Communications
- Peptides, Peptidomimetics, and Carbohydrate–Peptide Conjugates as Amyloidogenic Aggregation Inhibitors for Alzheimer’s Disease
- (2018) Philip Ryan et al. ACS Chemical Neuroscience
- Inhibition of protein misfolding and aggregation by natural phenolic compounds
- (2018) Zohra Dhouafli et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Gantenerumab: A Novel Human Anti-Aβ Antibody Demonstrates Sustained Cerebral Amyloid-β Binding and Elicits Cell-Mediated Removal of Human Amyloid-β
- (2018) Bernd Bohrmann et al. JOURNAL OF ALZHEIMERS DISEASE
- Resveratrol Brain Delivery for Neurological Disorders Prevention and Treatment
- (2018) Stephanie Andrade et al. Frontiers in Pharmacology
- Inhibition of amyloid fibril formation and disassembly of pre-formed fibrils by natural polyphenol rottlerin
- (2018) Katarina Siposova et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Structure–activity relations of rosmarinic acid derivatives for the amyloid β aggregation inhibition and antioxidant properties
- (2017) Riho Taguchi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Amyloid-β and tau complexity — towards improved biomarkers and targeted therapies
- (2017) Juan Carlos Polanco et al. Nature Reviews Neurology
- Design, synthesis, and evaluation of Trolox-conjugated amyloid-β C-terminal peptides for therapeutic intervention in an in vitro model of Alzheimer’s disease
- (2016) Takuya Arai et al. BIOORGANIC & MEDICINAL CHEMISTRY
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- Hematoxylin Inhibits Amyloid β-Protein Fibrillation and Alleviates Amyloid-Induced Cytotoxicity
- (2016) Yilong Tu et al. JOURNAL OF PHYSICAL CHEMISTRY B
- The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease
- (2016) Jeff Sevigny et al. NATURE
- Structural and fluctuational difference between two ends of Aβ amyloid fibril: MD simulations predict only one end has open conformations
- (2016) Hisashi Okumura et al. Scientific Reports
- Destabilization of Alzheimer’s Aβ42 Protofibrils with a Novel Drug Candidate wgx-50 by Molecular Dynamics Simulations
- (2015) Huai-Meng Fan et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Anti-amyloid Aggregation Activity of Natural Compounds: Implications for Alzheimer’s Drug Discovery
- (2015) Xian-Le Bu et al. MOLECULAR NEUROBIOLOGY
- Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity
- (2015) Wen-Jie Du et al. Scientific Reports
- Rationally Designed Peptoids Modulate Aggregation of Amyloid-Beta 40
- (2014) J. Phillip Turner et al. ACS Chemical Neuroscience
- Designed α-sheet peptides inhibit amyloid formation by targeting toxic oligomers
- (2014) Gene Hopping et al. eLife
- Nanomaterials for Reducing Amyloid Cytotoxicity
- (2013) Min Zhang et al. ADVANCED MATERIALS
- Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism
- (2013) S. I. A. Cohen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Peptides for Therapy and Diagnosis of Alzheimer's Disease
- (2012) Susanne Aileen Funke et al. CURRENT PHARMACEUTICAL DESIGN
- Structures of the Amyloid β-Peptides Aβ1–40 and Aβ1–42 as Influenced by pH and a d-Peptide
- (2012) Olujide O. Olubiyi et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Curcumin Binds to Aβ1–40 Peptides and Fibrils Stronger Than Ibuprofen and Naproxen
- (2012) Son Tung Ngo et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Destabilizing Alzheimer’s Aβ42Protofibrils with Morin: Mechanistic Insights from Molecular Dynamics Simulations
- (2010) Justin A. Lemkul et al. BIOCHEMISTRY
- Resveratrol Selectively Remodels Soluble Oligomers and Fibrils of Amyloid Aβ into Off-pathway Conformers
- (2010) Ali Reza A. Ladiwala et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Assessing the Stability of Alzheimer’s Amyloid Protofibrils Using Molecular Dynamics
- (2010) Justin A. Lemkul et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Natural products as a source of Alzheimer's drug leads
- (2010) Philip Williams et al. NATURAL PRODUCT REPORTS
- -Secretase: Successive Tripeptide and Tetrapeptide Release from the Transmembrane Domain of -Carboxyl Terminal Fragment
- (2009) M. Takami et al. JOURNAL OF NEUROSCIENCE
- Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation
- (2009) Ying Feng et al. NEUROTOXICOLOGY
- Inhibition of Amyloid β Protein Fibrillation by Polymeric Nanoparticles
- (2008) Celia Cabaleiro-Lago et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers
- (2008) Dagmar E Ehrnhoefer et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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