Alginate Oligosaccharide Prevents Acute Doxorubicin Cardiotoxicity by Suppressing Oxidative Stress and Endoplasmic Reticulum-Mediated Apoptosis

Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome AcidificationCLINICAL PERSPECTIVE

(2016) Dan L. Li et al.   CIRCULATION

Chemical Endoplasmic Reticulum Chaperone Alleviates Doxorubicin-Induced Cardiac DysfunctionNovelty and Significance

(2016) Hai Ying Fu et al.   CIRCULATION RESEARCH

The effects of different angiotensin II type 1 receptor blockers on the regulation of the ACE-AngII-AT1 and ACE2-Ang(1–7)-Mas axes in pressure overload-induced cardiac remodeling in male mice

(2016) Xingxu Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Sulforaphane protects the heart from doxorubicin-induced toxicity

(2015) Preeti Singh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Anti-inflammatory Activity of Guluronate Oligosaccharides Obtained by Oxidative Degradation from Alginate in Lipopolysaccharide-Activated Murine Macrophage RAW 264.7 Cells

(2015) Rui Zhou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Alginate-Derived Oligosaccharide Inhibits Neuroinflammation and Promotes Microglial Phagocytosis of β-Amyloid

(2015) Rui Zhou et al.   Marine Drugs

Cyclovirobuxine D Attenuates Doxorubicin-Induced Cardiomyopathy by Suppression of Oxidative Damage and Mitochondrial Biogenesis Impairment

(2015) Qian Guo et al.   Oxidative Medicine and Cellular Longevity

Bacillus subtilis KCTC 11782BP-Produced Alginate Oligosaccharide Effectively Suppresses Asthma via T-Helper Cell Type 2-Related Cytokines

(2015) Mi-Ae Bang et al.   PLoS One

Caspase-12 ablation preserves muscle function in the mdx mouse

(2014) Catherine Moorwood et al.   HUMAN MOLECULAR GENETICS

Emerging Paradigms in Cardiomyopathies Associated With Cancer Therapies

(2013) Bonnie Ky et al.   CIRCULATION RESEARCH

Changes in Cardiac Biomarkers During Doxorubicin Treatment of Pediatric Patients With High-Risk Acute Lymphoblastic Leukemia: Associations With Long-Term Echocardiographic Outcomes

(2012) Steven E. Lipshultz et al.   JOURNAL OF CLINICAL ONCOLOGY

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Development of doxorubicin-induced chronic cardiotoxicity in the B6C3F1 mouse model

(2012) Varsha G. Desai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Alginate oligosaccharide protects against endoplasmic reticulum- and mitochondrial-mediated apoptotic cell death and oxidative stress

(2011) Solaleh Khoramian Tusi et al.   BIOMATERIALS

Preparation, purification and characterization of alginate oligosaccharides degraded by alginate lyase from Pseudomonas sp. HZJ 216

(2011) Liyan Li et al.   CARBOHYDRATE RESEARCH

Hydrogen sulfide protects H9c2 cells against doxorubicin-induced cardiotoxicity through inhibition of endoplasmic reticulum stress

(2011) Xiu-Yu Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Doxorubicin Toxicity can be Ameliorated during Antioxidant L-Carnitine Supplementation

(2011) Othman A. Alshabanah et al.   Oxidative Medicine and Cellular Longevity

Nox2 NADPH Oxidase Promotes Pathologic Cardiac Remodeling Associated with Doxorubicin Chemotherapy

(2010) Y. Zhao et al.   CANCER RESEARCH

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Ablation of C/EBP Homologous Protein Attenuates Endoplasmic Reticulum–Mediated Apoptosis and Cardiac Dysfunction Induced by Pressure Overload

(2010) Hai Ying Fu et al.   CIRCULATION

Endoplasmic Reticulum Stress As a Therapeutic Target in Cardiovascular Disease

(2010) Tetsuo Minamino et al.   CIRCULATION RESEARCH

Long-term Cause-Specific Mortality Among Survivors of Childhood Cancer

(2010) Raoul C. Reulen   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

NADPH oxidases participate to doxorubicin-induced cardiac myocyte apoptosis

(2009) Mylène Gilleron et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SR/ER–mitochondrial local communication: Calcium and ROS

(2009) György Csordás et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells

(2009) Silvia Masciarelli et al.   MOLECULAR IMMUNOLOGY

Over-expression of a modified bifunctional apoptosis regulator protects against cardiac injury and doxorubicin-induced cardiotoxicity in transgenic mice

(2008) C. C. Chua et al.   CARDIOVASCULAR RESEARCH