PI-103 attenuates PI3K-AKT signaling and induces apoptosis in murineT-cell lymphoma

Controlled release of drug and better bioavailability using poly(lactic acid-co-glycolic acid) nanoparticles

(2016) Sanjeev K. Pandey et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

PI3K inhibitors as new cancer therapeutics: implications for clinical trial design

(2016) Cristian Massacesi et al.   OncoTargets and Therapy

Lymphoma incidence, survival and prevalence 2004–2014: sub-type analyses from the UK’s Haematological Malignancy Research Network

(2015) A Smith et al.   BRITISH JOURNAL OF CANCER

PI3K and AKT: Unfaithful Partners in Cancer

(2015) Seraina Faes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anticarcinogenic action of quercetin by downregulation of phosphatidylinositol 3-kinase (PI3K) and protein kinase C (PKC) via induction of p53 in hepatocellular carcinoma (HepG2) cell line

(2015) Akhilendra Kumar Maurya et al.   MOLECULAR BIOLOGY REPORTS

Abstract A07: Decline in the growth of murine T-cell lymphoma via modulation of PI3K signaling pathway: Key role of quercetin and PI-103

(2015) Akhilendra Kumar Maurya et al.   MOLECULAR CANCER THERAPEUTICS

Quercetin Regresses Dalton's Lymphoma Growth via Suppression of PI3K/AKT Signaling Leading to Upregulation of p53 and Decrease in Energy Metabolism

(2015) Akhilendra Kumar Maurya et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Long Term Effect of Curcumin in Restoration of Tumour Suppressor p53 and Phase-II Antioxidant Enzymes via Activation of Nrf2 Signalling and Modulation of Inflammation in Prevention of Cancer

(2015) Laxmidhar Das et al.   PLoS One

An Apoptotic ‘Eat Me’ Signal: Phosphatidylserine Exposure

(2015) Katsumori Segawa et al.   TRENDS IN CELL BIOLOGY

Modulation of PKC signaling and induction of apoptosis through suppression of reactive oxygen species and tumor necrosis factor receptor 1 (TNFR1): key role of quercetin in cancer prevention

(2015) Akhilendra Kumar Maurya et al.   TUMOR BIOLOGY

Status of PI3K/Akt/mTOR Pathway Inhibitors in Lymphoma

(2014) Jason R. Westin   Clinical Lymphoma Myeloma & Leukemia

Long-term effect of curcumin down-regulates expression of tumor necrosis factor-α and interleukin-6 via modulation of E26 transformation-specific protein and nuclear factor-κB transcription factors in livers of lymphoma bearing mice

(2014) Laxmidhar Das et al.   LEUKEMIA & LYMPHOMA

Evading apoptosis in cancer

(2013) Kaleigh Fernald et al.   TRENDS IN CELL BIOLOGY

Testosterone exerts antiapoptotic effects against H2O2 in C2C12 skeletal muscle cells through the apoptotic intrinsic pathway

(2012) Lucía Pronsato et al.   JOURNAL OF ENDOCRINOLOGY

Protein kinase Cα protects against multidrug resistance in human colon cancer cells

(2012) Se-Kyoung Lee et al.   MOLECULES AND CELLS

Involvement of PKCα activation in TF/VIIa/PAR2-induced proliferation, migration, and survival of colon cancer cell SW620

(2012) Biao Wu et al.   TUMOR BIOLOGY

Akt, FoxO and regulation of apoptosis

(2011) Xinbo Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Epidemiology of lymphomas

(2011) Eve Roman et al.   HISTOPATHOLOGY

Anti-carcinogenic action of ellagic acid mediated via modulation of oxidative stress regulated genes in Dalton lymphoma bearing mice

(2011) Sudha Mishra et al.   LEUKEMIA & LYMPHOMA

Correction: Identifying and Characterizing Nodes Important to Community Structure Using the Spectrum of the Graph

(2011) Yang Wang et al.   PLoS One

Drugging the PI3 Kinome: From Chemical Tools to Drugs in the Clinic

(2010) P. Workman et al.   CANCER RESEARCH

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Critical role of PI3K signaling for NF- B-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells

(2010) B. Kloo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer-derived mutations in the regulatory subunit p85  of phosphoinositide 3-kinase function through the catalytic subunit p110 

(2010) M. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activity of any class IA PI3K isoform can sustain cell proliferation and survival

(2010) L. C. Foukas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Somatic Mutations in p85α Promote Tumorigenesis through Class IA PI3K Activation

(2009) Bijay S. Jaiswal et al.   CANCER CELL

Caspases and Kinases in a Death Grip

(2009) Manabu Kurokawa et al.   CELL

FrequentPIK3CAgene amplification and its clinical significance in colorectal cancer

(2009) Zeenath Jehan et al.   JOURNAL OF PATHOLOGY

PIK3CA alterations in Middle Eastern ovarian cancers

(2009) Jehad Abubaker et al.   Molecular Cancer

Protein kinase Cα: disease regulator and therapeutic target

(2009) Olga Konopatskaya et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

PI3K pathway alterations in cancer: variations on a theme

(2008) T L Yuan et al.   ONCOGENE

Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease

(2008) Anumantha G Kanthasamy et al.   Molecular Brain