Driver Mutations Dictate the Immunologic Landscape and Response to Checkpoint Immunotherapy of Glioblastoma
出版年份 2023 全文链接
标题
Driver Mutations Dictate the Immunologic Landscape and Response to Checkpoint Immunotherapy of Glioblastoma
作者
关键词
-
出版物
Cancer Immunology Research
Volume 11, Issue 5, Pages 629-645
出版商
American Association for Cancer Research (AACR)
发表日期
2023-03-07
DOI
10.1158/2326-6066.cir-22-0655
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression
- (2022) Alan T. Yeo et al. NATURE IMMUNOLOGY
- EGFRvIII tumorigenicity requires PDGFRA co-signaling and reveals therapeutic vulnerabilities in glioblastoma
- (2021) Alan T. Yeo et al. ONCOGENE
- Exploring the longitudinal glioma microenvironment landscape uncovers reprogrammed pro-tumorigenic neutrophils in the bone marrow
- (2021) Prerna Magod et al. Cell Reports
- Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response
- (2021) Kevin C. Johnson et al. NATURE GENETICS
- Myeloid-Derived Suppressor Cells: A Propitious Road to Clinic
- (2021) Amit Grover et al. Cancer Discovery
- Immunotherapy Resistance in Glioblastoma
- (2021) Elaina J. Wang et al. Frontiers in Genetics
- Targeted deletion of PD-1 in myeloid cells induces antitumor immunity
- (2020) Laura Strauss et al. Science Immunology
- Myeloid-derived suppressor cell subsets drive glioblastoma growth in a sex-specific manner
- (2020) Defne Bayik et al. Cancer Discovery
- Genetic driver mutations introduced in identical cell‐of‐origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade
- (2020) Zhihong Chen et al. GLIA
- The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes
- (2020) Floris Dammeijer et al. CANCER CELL
- Determining cell type abundance and expression from bulk tissues with digital cytometry
- (2019) Aaron M. Newman et al. NATURE BIOTECHNOLOGY
- Mechanisms of ERBB3 Action in Human Neoplasia
- (2019) Laurel Black et al. AMERICAN JOURNAL OF PATHOLOGY
- Mechanisms of immunotherapy resistance: lessons from glioblastoma
- (2019) Christopher M. Jackson et al. NATURE IMMUNOLOGY
- Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer
- (2019) Diletta Di Mitri et al. Cell Reports
- Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape
- (2018) Max D. Wellenstein et al. IMMUNITY
- Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms
- (2018) Marco Bezzi et al. NATURE MEDICINE
- Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies
- (2018) Zhenyi An et al. ONCOGENE
- Role of PD-1 during effector CD8 T cell differentiation
- (2018) Eunseon Ahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacokinetics of the Oral Selective CXCR2 Antagonist AZD5069: A Summary of Eight Phase I Studies in Healthy Volunteers
- (2018) Marie Cullberg et al. Drugs in research & development
- Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
- (2018) Mana Taki et al. Nature Communications
- Myeloid-Derived Suppressor Cells Hinder the Anti-Cancer Activity of Immune Checkpoint Inhibitors
- (2018) Rebekka Weber et al. Frontiers in Immunology
- A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine
- (2018) Hyun Jung Jun et al. Nature Communications
- Immunotherapies for malignant glioma
- (2017) Vassiliki A. Boussiotis et al. ONCOGENE
- Combination immunotherapy: a road map
- (2017) Patrick A. Ott et al. Journal for ImmunoTherapy of Cancer
- Myeloid-Derived Suppressor Cell Subset Accumulation in Renal Cell Carcinoma Parenchyma Is Associated with Intratumoral Expression of IL1β, IL8, CXCL5, and Mip-1α
- (2016) Yana G. Najjar et al. CLINICAL CANCER RESEARCH
- Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
- (2016) Vincenzo Bronte et al. Nature Communications
- Evaluating Multiplexed Quantitative Phosphopeptide Analysis on a Hybrid Quadrupole Mass Filter/Linear Ion Trap/Orbitrap Mass Spectrometer
- (2015) Brian K. Erickson et al. ANALYTICAL CHEMISTRY
- Multiplexed, Proteome-Wide Protein Expression Profiling: Yeast Deubiquitylating Enzyme Knockout Strains
- (2015) Marta Isasa et al. JOURNAL OF PROTEOME RESEARCH
- The safety and tolerability of oral AZD5069, a selective CXCR2 antagonist, in patients with moderate-to-severe COPD
- (2015) A.M. Kirsten et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation
- (2015) Nikolaos Patsoukis et al. Nature Communications
- Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression
- (2015) G. Wang et al. Cancer Discovery
- MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes
- (2014) Graeme C. McAlister et al. ANALYTICAL CHEMISTRY
- Disruption of CXCR2-Mediated MDSC Tumor Trafficking Enhances Anti-PD1 Efficacy
- (2014) S. L. Highfill et al. Science Translational Medicine
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- Asymmetric kinase dimer formation is crucial for the activation of oncogenic EGFRvIII but not for ERBB3 phosphorylation
- (2013) Rama Kancha et al. Cell Communication and Signaling
- PD-1 Increases PTEN Phosphatase Activity While Decreasing PTEN Protein Stability by Inhibiting Casein Kinase 2
- (2013) Nikolaos Patsoukis et al. MOLECULAR AND CELLULAR BIOLOGY
- Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice
- (2012) Junjie Mei et al. JOURNAL OF CLINICAL INVESTIGATION
- Selective Effects of PD-1 on Akt and Ras Pathways Regulate Molecular Components of the Cell Cycle and Inhibit T Cell Proliferation
- (2012) N. Patsoukis et al. Science Signaling
- G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands
- (2011) A. Kohler et al. BLOOD
- Chronic Activation of Wild-Type Epidermal Growth Factor Receptor and Loss of Cdkn2a Cause Mouse Glioblastoma Formation
- (2011) J. Acquaviva et al. CANCER RESEARCH
- MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics
- (2011) Lily Ting et al. NATURE METHODS
- Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme
- (2011) H J Jun et al. ONCOGENE
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression
- (2010) Edward L. Huttlin et al. CELL
- A Cre/LoxP conditional luciferase reporter transgenic mouse for bioluminescence monitoring of tumorigenesis
- (2009) Steve Woolfenden et al. GENESIS
- PD-1 signaling in primary T cells
- (2009) James L. Riley IMMUNOLOGICAL REVIEWS
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification
- (2009) Athanasia Spandidos et al. NUCLEIC ACIDS RESEARCH
- Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis
- (2009) Haihao Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance
- (2008) Athanasia Spandidos et al. BMC GENOMICS
- Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
- (2008) Da Wei Huang et al. NUCLEIC ACIDS RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started