Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response
出版年份 2021 全文链接
标题
Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response
作者
关键词
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出版物
NATURE GENETICS
Volume 53, Issue 10, Pages 1456-1468
出版商
Springer Science and Business Media LLC
发表日期
2021-10-01
DOI
10.1038/s41588-021-00926-8
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Twelve years of SAMtools and BCFtools
- (2021) Petr Danecek et al. GigaScience
- Spatial concordance of DNA methylation classification in diffuse glioma
- (2021) Niels Verburg et al. NEURO-ONCOLOGY
- Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma
- (2020) Aparna Bhaduri et al. Cell Stem Cell
- The repertoire of mutational signatures in human cancer
- (2020) Ludmil B. Alexandrov et al. NATURE
- Single-cell transcriptional diversity is a hallmark of developmental potential
- (2020) Gunsagar S. Gulati et al. SCIENCE
- A sensitive assay for dNTPs based on long synthetic oligonucleotides, EvaGreen dye and inhibitor-resistant high-fidelity DNA polymerase
- (2020) Janne Purhonen et al. NUCLEIC ACIDS RESEARCH
- Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers
- (2020) Hoon Kim et al. NATURE GENETICS
- Exploring the landscape of focal amplifications in cancer using AmpliconArchitect
- (2019) Viraj Deshpande et al. Nature Communications
- Evolutionary Trajectories of IDHWT Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis
- (2019) Verena Körber et al. CANCER CELL
- Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia
- (2019) Federico Gaiti et al. NATURE
- Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells
- (2019) Graham MacLeod et al. Cell Reports
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
- (2019) Cyril Neftel et al. CELL
- Single-Cell Multi-omic Integration Compares and Contrasts Features of Brain Cell Identity
- (2019) Joshua D. Welch et al. CELL
- The phenotypes of proliferating glioblastoma cells reside on a single axis of variation
- (2019) Lin Wang et al. Cancer Discovery
- Functional Enhancers Shape Extrachromosomal Oncogene Amplifications
- (2019) Andrew R. Morton et al. CELL
- Longitudinal molecular trajectories of diffuse glioma in adults
- (2019) Floris P. Barthel et al. NATURE
- Circular ecDNA promotes accessible chromatin and high oncogene expression
- (2019) Sihan Wu et al. NATURE
- Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells
- (2019) Irene Hernando-Herraez et al. Nature Communications
- Multi-omics profiling of mouse gastrulation at single-cell resolution
- (2019) Ricard Argelaguet et al. NATURE
- Snakemake—a scalable bioinformatics workflow engine
- (2018) Johannes Köster et al. BIOINFORMATICS
- Cellular Stress Associated with Aneuploidy
- (2018) Jin Zhu et al. DEVELOPMENTAL CELL
- DNA methylation-based classification of central nervous system tumours
- (2018) David Capper et al. NATURE
- Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma
- (2018) Ana C. deCarvalho et al. NATURE GENETICS
- A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence
- (2018) Camila Ferreira de Souza et al. Cell Reports
- MutationalPatterns: comprehensive genome-wide analysis of mutational processes
- (2018) Francis Blokzijl et al. Genome Medicine
- The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
- (2018) Johanna Klughammer et al. NATURE MEDICINE
- Pan-cancer deconvolution of tumour composition using DNA methylation
- (2018) Ankur Chakravarthy et al. Nature Communications
- Single-cell transcriptome analysis of lineage diversity in high-grade glioma
- (2018) Jinzhou Yuan et al. Genome Medicine
- High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations
- (2018) Tony Hui et al. Stem Cell Reports
- Dimensionality reduction for visualizing single-cell data using UMAP
- (2018) Etienne Becht et al. NATURE BIOTECHNOLOGY
- Single-cell multiomics sequencing and analyses of human colorectal cancer
- (2018) Shuhui Bian et al. SCIENCE
- Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
- (2017) Sydney M. Shaffer et al. NATURE
- Targeting glioma stem cells through combined BMI1 and EZH2 inhibition
- (2017) Xun Jin et al. NATURE MEDICINE
- SCENIC: single-cell regulatory network inference and clustering
- (2017) Sara Aibar et al. NATURE METHODS
- Epigenetic plasticity and the hallmarks of cancer
- (2017) William A. Flavahan et al. SCIENCE
- Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
- (2017) Andrew S. Venteicher et al. SCIENCE
- Single-cell epigenomics: Recording the past and predicting the future
- (2017) Gavin Kelsey et al. SCIENCE
- Impact of cytosine methylation on DNA binding specificities of human transcription factors
- (2017) Yimeng Yin et al. SCIENCE
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma
- (2016) Michele Ceccarelli et al. CELL
- DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation
- (2016) Matthias Farlik et al. Cell Stem Cell
- Tumour hypoxia causes DNA hypermethylation by reducing TET activity
- (2016) Bernard Thienpont et al. NATURE
- Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma
- (2016) Itay Tirosh et al. NATURE
- Near-optimal probabilistic RNA-seq quantification
- (2016) Nicolas L Bray et al. NATURE BIOTECHNOLOGY
- Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity
- (2016) Christof Angermueller et al. NATURE METHODS
- 5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients
- (2016) Kevin C. Johnson et al. Nature Communications
- LOLA: enrichment analysis for genomic region sets and regulatory elements in R and Bioconductor
- (2015) Nathan C. Sheffield et al. BIOINFORMATICS
- dendextend: an R package for visualizing, adjusting and comparing trees of hierarchical clustering
- (2015) Tal Galili BIOINFORMATICS
- DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors
- (2015) Tali Mazor et al. CANCER CELL
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Spatial reconstruction of single-cell gene expression data
- (2015) Rahul Satija et al. NATURE BIOTECHNOLOGY
- Interactive analysis and assessment of single-cell copy-number variations
- (2015) Tyler Garvin et al. NATURE METHODS
- Profiling DNA methylome landscapes of mammalian cells with single-cell reduced-representation bisulfite sequencing
- (2015) Hongshan Guo et al. Nature Protocols
- Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas
- (2015) NEW ENGLAND JOURNAL OF MEDICINE
- Cyclin-dependent kinase 2 (CDK2) is a key mediator for EGF-induced cell transformation mediated through the ELK4/c-Fos signaling pathway
- (2015) C Peng et al. ONCOGENE
- PhyloWGS: Reconstructing subclonal composition and evolution from whole-genome sequencing of tumors
- (2015) Amit G Deshwar et al. GENOME BIOLOGY
- Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data
- (2014) F. Favero et al. ANNALS OF ONCOLOGY
- Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia
- (2014) Dan A. Landau et al. CANCER CELL
- TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data
- (2014) Gavin Ha et al. GENOME RESEARCH
- Cancer Epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance
- (2014) Hariharan Easwaran et al. MOLECULAR CELL
- A promoter-level mammalian expression atlas
- (2014) NATURE
- Track data hubs enable visualization of user-defined genome-wide annotations on the UCSC Genome Browser
- (2013) B. J. Raney et al. BIOINFORMATICS
- GSVA: gene set variation analysis for microarray and RNA-Seq data
- (2013) Sonja Hänzelmann et al. BMC BIOINFORMATICS
- Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
- (2013) Krishna P.L. Bhat et al. CANCER CELL
- The CpG Island Methylator Phenotype: What's in a Name?
- (2013) L. A. E. Hughes et al. CANCER RESEARCH
- What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
- (2013) J.-A. Losman et al. GENES & DEVELOPMENT
- Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing
- (2013) H. Guo et al. GENOME RESEARCH
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation
- (2012) Amnon Koren et al. AMERICAN JOURNAL OF HUMAN GENETICS
- IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
- (2012) Sevin Turcan et al. NATURE
- Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
- (2012) Gilad Landan et al. NATURE GENETICS
- Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications
- (2011) Felix Krueger et al. BIOINFORMATICS
- Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genes
- (2010) Francesca Orso et al. BMC GENOMICS
- Hypoxia inducible factors in cancer stem cells
- (2010) J M Heddleston et al. BRITISH JOURNAL OF CANCER
- Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
- (2010) Houtan Noushmehr et al. CANCER CELL
- A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
- (2010) Sreenath V. Sharma et al. CELL
- Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells
- (2009) Zhizhong Li et al. CANCER CELL
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
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