Modular, pumpless body-on-a-chip platform for the co-culture of GI tract epithelium and 3D primary liver tissue
出版年份 2016 全文链接
标题
Modular, pumpless body-on-a-chip platform for the co-culture of GI tract epithelium and 3D primary liver tissue
作者
关键词
-
出版物
LAB ON A CHIP
Volume 16, Issue 14, Pages 2719-2729
出版商
Royal Society of Chemistry (RSC)
发表日期
2016-06-23
DOI
10.1039/c6lc00461j
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
- (2015) Ilka Maschmeyer et al. LAB ON A CHIP
- Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow
- (2015) Mandy B. Esch et al. LAB ON A CHIP
- Bioreactor technologies to support liver function in vitro
- (2014) Mohammad R. Ebrahimkhani et al. ADVANCED DRUG DELIVERY REVIEWS
- How multi-organ microdevices can help foster drug development
- (2014) Mandy B. Esch et al. ADVANCED DRUG DELIVERY REVIEWS
- First pass intestinal and liver metabolism of paracetamol in a microfluidic platform coupled with a mathematical modeling as a means of evaluating ADME processes in humans
- (2014) Jean Matthieu Prot et al. BIOTECHNOLOGY AND BIOENGINEERING
- Three dimensional human small intestine models for ADME-Tox studies
- (2014) Jiajie Yu et al. DRUG DISCOVERY TODAY
- Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury
- (2014) Mandy B. Esch et al. LAB ON A CHIP
- 3-D Intestinal Scaffolds for Evaluating the Therapeutic Potential of Probiotics
- (2014) Cait M. Costello et al. MOLECULAR PHARMACEUTICS
- Inflammatory findings on species extrapolations: humans are definitely no 70-kg mice
- (2013) Marcel Leist et al. ARCHIVES OF TOXICOLOGY
- Phase II and Phase III attrition rates 2011–2012
- (2013) John Arrowsmith et al. NATURE REVIEWS DRUG DISCOVERY
- Genomic responses in mouse models poorly mimic human inflammatory diseases
- (2013) Junhee Seok et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity
- (2013) Radina Kostadinova et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- On chip porous polymer membranes for integration of gastrointestinal tract epithelium with microfluidic ‘body-on-a-chip’ devices
- (2012) Mandy Brigitte Esch et al. BIOMEDICAL MICRODEVICES
- Investigation of ifosfamide nephrotoxicity induced in a liver-kidney co-culture biochip
- (2012) Leila Choucha-Snouber et al. BIOTECHNOLOGY AND BIOENGINEERING
- In vitro 3D human small intestinal villous model for drug permeability determination
- (2012) Jiajie Yu et al. BIOTECHNOLOGY AND BIOENGINEERING
- Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow
- (2012) Hyun Jung Kim et al. LAB ON A CHIP
- Reinventing clinical trials
- (2012) Malorye Allison NATURE BIOTECHNOLOGY
- LIFE SCIENCE TECHNOLOGIES: Animal-Free Toxicology: Sometimes, in Vitro is Better
- (2012) J. M. Perkel SCIENCE
- First-Pass Metabolism via UDP-Glucuronosyltransferase: a Barrier to Oral Bioavailability of Phenolics
- (2011) Baojian Wu et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Phase II failures: 2008–2010
- (2011) John Arrowsmith NATURE REVIEWS DRUG DISCOVERY
- Ethical and Scientific Considerations Regarding Animal Testing and Research
- (2011) Hope R. Ferdowsian et al. PLoS One
- Predictive toxicology using systemic biology and liver microfluidic “on chip” approaches: Application to acetaminophen injury
- (2011) Jean-Matthieu Prot et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- A microfluidic device for a pharmacokinetic–pharmacodynamic (PK–PD) model on a chip
- (2010) Jong Hwan Sung et al. LAB ON A CHIP
- Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity
- (2009) Gretchen J. Mahler et al. BIOTECHNOLOGY AND BIOENGINEERING
- Quantification of chemical-polymer surface interactions in microfluidic cell culture devices
- (2009) Hui Xu et al. BIOTECHNOLOGY PROGRESS
- Towards a human-on-chip: Culturing multiple cell types on a chip with compartmentalized microenvironments
- (2009) Chi Zhang et al. LAB ON A CHIP
- Survey of the Quality of Experimental Design, Statistical Analysis and Reporting of Research Using Animals
- (2009) Carol Kilkenny et al. PLoS One
- A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers
- (2008) Daniel A. Tatosian et al. BIOTECHNOLOGY AND BIOENGINEERING
- Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability☆
- (2008) Gretchen J. Mahler et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Development of a Microscale Cell Culture Analog To Probe Naphthalene Toxicity
- (2004) Kwanchanok Viravaidya et al. BIOTECHNOLOGY PROGRESS
- Incorporation of 3T3-L1 Cells To Mimic Bioaccumulation in a Microscale Cell Culture Analog Device for Toxicity Studies
- (2004) Kwanchanok Viravaidya et al. BIOTECHNOLOGY PROGRESS
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