Integrating Bulk-seq and Single-cell-seq Reveals Estrogen and MAPK Pathways Associating with Neuroblastoma Outcome

Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma

(2021) Selina Jansky et al.   NATURE GENETICS

oncoPredict: an R package for predicting in vivo or cancer patient drug response and biomarkers from cell line screening data

(2021) Danielle Maeser et al.   BRIEFINGS IN BIOINFORMATICS

A review of the biological and clinical implications of RAS-MAPK pathway alterations in neuroblastoma

(2021) Vid Mlakar et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The MYC oncogene — the grand orchestrator of cancer growth and immune evasion

(2021) Renumathy Dhanasekaran et al.   Nature Reviews Clinical Oncology

IOBR: Multi-Omics Immuno-Oncology Biological Research to Decode Tumor Microenvironment and Signatures

(2021) Dongqiang Zeng et al.   Frontiers in Immunology

The role of delta-like non-canonical Notch ligand 1 (DLK1) in cancer

(2021) James F H Pittaway et al.   ENDOCRINE-RELATED CANCER

Emerging Roles of DLK1 in the Stem Cell Niche and Cancer Stemness

(2021) Elisa Stellaria Grassi et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

NTRK1/TrkA Activation Overrides the G2/M-Checkpoint upon Irradiation

(2021) Christina Hassiepen et al.   Cancers

Identification of a Five-Gene Signature Derived From MYCN Amplification and Establishment of a Nomogram for Predicting the Prognosis of Neuroblastoma

(2021) Yuren Xia et al.   Frontiers in Molecular Biosciences

Monitoring Immune Responses in Neuroblastoma Patients during Therapy

(2020) Celina L. Szanto et al.   Cancers

ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen

(2020) Anieta M. Sieuwerts et al.   Cancers

Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma

(2020) Lucas Moreno et al.   EUROPEAN JOURNAL OF CANCER

Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations

(2020) Samuel W. Brady et al.   Nature Communications

Targeting the p53-MDM2 pathway for neuroblastoma therapy: Rays of hope

(2020) Atif Zafar et al.   CANCER LETTERS

The immune landscape of neuroblastoma: Challenges and opportunities for novel therapeutic strategies in pediatric oncology

(2020) Judith Wienke et al.   EUROPEAN JOURNAL OF CANCER

Quizartinib (AC220): a promising option for acute myeloid leukemia

(2019) Fang Zhou et al.   Drug Design Development and Therapy

FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications

(2019) Julhash U. Kazi et al.   PHYSIOLOGICAL REVIEWS

Transfer of regulatory knowledge from human to mouse for functional genomic analysis

(2019) Christian H. Holland et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Estrogen Receptor pathway activity score to predict clinical response or resistance to neo-adjuvant endocrine therapy in primary breast cancer

(2019) Marcia A. Inda et al.   MOLECULAR CANCER THERAPEUTICS

FLT3 mutations in acute myeloid leukemia: Therapeutic paradigm beyond inhibitor development

(2019) Hitoshi Kiyoi et al.   CANCER SCIENCE

Whole genome sequencing analysis for cancer genomics and precision medicine

(2018) Hidewaki Nakagawa et al.   CANCER SCIENCE

Oncogenic Signaling Pathways in The Cancer Genome Atlas

(2018) Francisco Sanchez-Vega et al.   CELL

Spontaneous regression of neuroblastoma

(2018) Garrett M. Brodeur   CELL AND TISSUE RESEARCH

MYCN-amplified neuroblastoma maintains an aggressive and undifferentiated phenotype by deregulation of estrogen and NGF signaling

(2018) Johanna Dzieran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibiting TRK Proteins in Clinical Cancer Therapy

(2018) Allison Lange et al.   Cancers

Update on neuroblastoma

(2018) Erika A. Newman et al.   JOURNAL OF PEDIATRIC SURGERY

NTRK fusion-positive cancers and TRK inhibitor therapy

(2018) Emiliano Cocco et al.   Nature Reviews Clinical Oncology

Identification of Potential Prognostic Genes for Neuroblastoma

(2018) Xiaodan Zhong et al.   Frontiers in Genetics

Precision Oncology: The Road Ahead

(2017) Daniela Senft et al.   TRENDS IN MOLECULAR MEDICINE

Dinutuximab for the treatment of pediatric patients with high-risk neuroblastoma

(2016) Jaume Mora   Expert Review of Clinical Pharmacology

Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): the TRIPOD Statement

(2015) G. S. Collins et al.   BRITISH JOURNAL OF SURGERY

Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

(2015) Thomas F Eleveld et al.   NATURE GENETICS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Tumor-infiltrating T lymphocytes improve clinical outcome of therapy-resistant neuroblastoma

(2015) Marco Mina et al.   OncoImmunology

Regularization Paths for Generalized Linear Models via Coordinate Descent

(2015) Jerome Friedman et al.   Journal of Statistical Software

Rare Variants in TP53 and Susceptibility to Neuroblastoma

(2014) Sharon J. Diskin et al.   JNCI-Journal of the National Cancer Institute

NF-κB Signaling Pathway Confers Neuroblastoma Cells Migration and Invasion Ability via the Regulation of CXCR4

(2014) Kun Yang   MEDICAL SCIENCE MONITOR

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Possible roles of DLK1 in the Notch pathway during development and disease

(2012) Farah A. Falix et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A Three-Gene Expression Signature Model for Risk Stratification of Patients with Neuroblastoma

(2012) I. Garcia et al.   CLINICAL CANCER RESEARCH

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

(2010) Matthew D. Wilkerson et al.   BIOINFORMATICS

Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(2009) David A. Barbie et al.   NATURE

Mechanisms of change in gene copy number

(2009) P. J. Hastings et al.   NATURE REVIEWS GENETICS

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

Expression of KIT and PDGFR is associated with a good prognosis in neuroblastoma

(2007) Akira Shimada et al.   PEDIATRIC BLOOD & CANCER