Myo-Inositol and D-Chiro-Inositol as Modulators of Ovary Steroidogenesis: A Narrative Review

Phosphatidic acid inhibits inositol synthesis by inducing nuclear translocation of kinase IP6K1 and repression of myo-inositol-3-P synthase

(2022) Pablo Lazcano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bioactivity of Inositol Phosphates

(2021) Ivana Vucenik   MOLECULES

D-chiro-inositol, an aromatase down-modulator, increases androgens and reduces estrogens in male volunteers: a pilot study

(2021) Giovanni Monastra et al.   Basic and Clinical Andrology

miR-125a-5p impairs the metastatic potential in breast cancer via IP6K1 targeting

(2021) Mirko Minini et al.   CANCER LETTERS

Inositols: From Established Knowledge to Novel Approaches

(2021) Simona Dinicola et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting the Inositol Pyrophosphate Biosynthetic Enzymes in Metabolic Diseases

(2020) Sandip Mukherjee et al.   MOLECULES

Biosynthesis and biology of mammalian GPI-anchored proteins

(2020) Taroh Kinoshita   Open Biology

Effects of D-Chiro-Inositol on Glucose Metabolism in db/db Mice and the Associated Underlying Mechanisms

(2020) Chunxue Fan et al.   Frontiers in Pharmacology

An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels

(2020) Hayley Whitfield et al.   BIOCHEMICAL JOURNAL

Biodynamic Interfaces Are Essential for Human–Environment Interactions

(2020) Manish Arora et al.   BIOESSAYS

An update on the use of inositols in preventing gestational diabetes mellitus (GDM) and neural tube defects (NTDs)

(2020) Fabio Facchinetti et al.   Expert Opinion on Drug Metabolism & Toxicology

The Key Role of IP6K: A Novel Target for Anticancer Treatments?

(2020) Mirko Minini et al.   MOLECULES

Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry

(2020) Danye Qiu et al.   Nature Communications

Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions

(2019) R. Fiume et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ITPK1 mediates the lipid-independent synthesis of inositol phosphates controlled by metabolism

(2019) Yann Desfougères et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myo-Inositol and Its Derivatives: Their Emerging Role in the Treatment of Human Diseases

(2019) Dhani Raj Chhetri   Frontiers in Pharmacology

Metabolic networks classification and knowledge discovery by information granulation

(2019) Alessio Martino et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Effects of myo-inositol plus alpha-lactalbumin in myo-inositol-resistant PCOS women

(2018) Mario Montanino Oliva et al.   Journal of Ovarian Research

Alpha-lactalbumin effect on myo-inositol intestinal absorption: in vivo and in vitro

(2018) Giovanni Monastra et al.   Current Drug Delivery

Myo-inositol and D-chiro-inositol (40:1) reverse histological and functional features of polycystic ovary syndrome in a mouse model

(2018) Arturo Bevilacqua et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inositols in Insulin Signaling and Glucose Metabolism

(2018) Arturo Bevilacqua et al.   International Journal of Endocrinology

Myo-inositol administration positively effects ovulation induction and intrauterine insemination in patients with polycystic ovary syndrome: a prospective, controlled, randomized trial

(2017) Özlen Emekçi Özay et al.   GYNECOLOGICAL ENDOCRINOLOGY

Nutritional and Acquired Deficiencies in Inositol Bioavailability. Correlations with Metabolic Disorders

(2017) Simona Dinicola et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Importance of Radioactive Labelling to Elucidate Inositol Polyphosphate Signalling

(2017) Miranda S. C. Wilson et al.   Topics in Current Chemistry

Phosphate, inositol and polyphosphates

(2016) T. M. Livermore et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Inositol induces mesenchymal-epithelial reversion in breast cancer cells through cytoskeleton rearrangement

(2016) Simona Dinicola et al.   EXPERIMENTAL CELL RESEARCH

Pharmacodynamics and pharmacokinetics of inositol(s) in health and disease

(2016) Mariano Bizzarri et al.   Expert Opinion on Drug Metabolism & Toxicology

Modulation of gonadotrophin induced steroidogenic enzymes in granulosa cells by d-chiroinositol

(2016) Sandro Sacchi et al.   Reproductive Biology and Endocrinology

Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate

(2016) Mariano Bizzarri et al.   International Journal of Endocrinology

The “Other” Inositols and Their Phosphates: Synthesis, Biology, and Medicine (with Recent Advances in myo -Inositol Chemistry)

(2015) Mark P. Thomas et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reflections on inositol(s) for PCOS therapy: steps toward success

(2015) John E. Nestler et al.   GYNECOLOGICAL ENDOCRINOLOGY

Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance

(2014) Zdravko Kamenov et al.   GYNECOLOGICAL ENDOCRINOLOGY

Hyperinsulinemia Alters Myoinositol to d-chiroinositol Ratio in the Follicular Fluid of Patients With PCOS

(2014) Vittorio Unfer et al.   Reproductive Sciences

Paleobiological Perspectives on Early Eukaryotic Evolution

(2014) A. H. Knoll   Cold Spring Harbor Perspectives in Biology

Inositol pyrophosphates: between signalling and metabolism

(2013) Miranda S. C. Wilson et al.   BIOCHEMICAL JOURNAL

Potential role and therapeutic interests of myo-inositol in metabolic diseases

(2013) Marine L. Croze et al.   BIOCHIMIE

Decreased myo-inositol to chiro-inositol (M/C) ratios and increased M/C epimerase activity in PCOS theca cells demonstrate increased insulin sensitivity compared to controls

(2013) Douglas Heimark et al.   ENDOCRINE JOURNAL

Comparison between effects of myo-inositol andd-chiro-inositol on ovarian function and metabolic factors in women with PCOS

(2013) Alfonsa Pizzo et al.   GYNECOLOGICAL ENDOCRINOLOGY

Determination of neo- and d-chiro-Inositol Hexakisphosphate in Soils by Solution 31P NMR Spectroscopy

(2012) Benjamin L. Turner et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Effects of myo-inositol in women with PCOS: a systematic review of randomized controlled trials

(2012) V. Unfer et al.   GYNECOLOGICAL ENDOCRINOLOGY

Regulation of Insulin Signaling and Glucose Transporter 4 (GLUT4) Exocytosis by Phosphatidylinositol 3,4,5-Trisphosphate (PIP3) Phosphatase, Skeletal Muscle, and Kidney Enriched Inositol Polyphosphate Phosphatase (SKIP)

(2012) Takeshi Ijuin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Does metformin affect the ovarian response to gonadotropins for in vitro fertilization treatment in patients with polycystic ovary syndrome and reduced ovarian reserve? A randomized controlled trial

(2011) Stefano Palomba et al.   FERTILITY AND STERILITY

The D-chiro-inositol paradox in the ovary

(2011) Gianfranco Carlomagno et al.   FERTILITY AND STERILITY

The cellular language of myo-inositol signaling

(2011) Glenda E. Gillaspy   NEW PHYTOLOGIST

Influence of Inositol Pyrophosphates on Cellular Energy Dynamics

(2011) Z. Szijgyarto et al.   SCIENCE

Inositol Pyrophosphates Inhibit Akt Signaling, Thereby Regulating Insulin Sensitivity and Weight Gain

(2010) Anutosh Chakraborty et al.   CELL

SYMPOSIUM REVIEW: Phosphoinositides: lipid regulators of membrane proteins

(2010) Björn H. Falkenburger et al.   JOURNAL OF PHYSIOLOGY-LONDON

p53-mediated apoptosis requires inositol hexakisphosphate kinase-2

(2010) M. A. Koldobskiy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin and hyperandrogenism in women with polycystic ovary syndrome

(2009) Catherine G. Baptiste et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Insulin-stimulated release of d-chiro-inositol–containing inositolphosphoglycan mediator correlates with insulin sensitivity in women with polycystic ovary syndrome

(2008) Kai I. Cheang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Akt phosphorylation and nuclear phosphoinositide association mediate mRNA export and cell proliferation activities by ALY

(2008) M. Okada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA