7-Ketocholesterol accelerates pancreatic β-cell senescence by inhibiting the SIRT1/CDK4–Rb–E2F1 signaling pathway
出版年份 2023 全文链接
标题
7-Ketocholesterol accelerates pancreatic β-cell senescence by inhibiting the SIRT1/CDK4–Rb–E2F1 signaling pathway
作者
关键词
-
出版物
Islets
Volume 15, Issue 1, Pages -
出版商
Informa UK Limited
发表日期
2023-06-02
DOI
10.1080/19382014.2023.2219105
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Lipids as Regulators of Cellular Senescence
- (2022) Shruthi Hamsanathan et al. Frontiers in Physiology
- Sulfated Fucogalactan From Laminaria Japonica Ameliorates β-Cell Failure by Attenuating Mitochondrial Dysfunction via SIRT1–PGC1-α Signaling Pathway Activation
- (2022) Nan Wu et al. Frontiers in Endocrinology
- An insight on 7- ketocholesterol mediated inflammation in atherosclerosis and potential therapeutics
- (2021) Sangeetha Ravi et al. STEROIDS
- Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: Potential for the prevention of age-related diseases
- (2021) T. Nury et al. AGEING RESEARCH REVIEWS
- The Influence of Cell Cycle Regulation on Chemotherapy
- (2021) Ying Sun et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Aging of the cells: Insight into cellular senescence and detection Methods
- (2020) Nor Shaheera Mohamad Kamal et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Epigenetic modification and therapeutic targets of diabetes mellitus
- (2020) Rajveer Singh et al. BIOSCIENCE REPORTS
- Functional changes in beta cells during ageing and senescence
- (2020) Cristina Aguayo-Mazzucato DIABETOLOGIA
- Senescence and the SASP: many therapeutic avenues
- (2020) Jodie Birch et al. GENES & DEVELOPMENT
- Resveratrol attenuates excessive ethanol exposure-induced β-cell senescence in rats: A critical role for the NAD+/SIRT1-p38MAPK/p16 pathway
- (2020) Gang Luo et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Connecting pancreatic islet lipid metabolism with insulin secretion and the development of type 2 diabetes
- (2019) Yumi Imai et al. Annals of the New York Academy of Sciences
- Cholesterol metabolism, pancreatic β-cell function and diabetes
- (2019) Carla Perego et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Angiotensin II‐induced redox‐sensitive SGLT1 and 2 expression promotes high glucose‐induced endothelial cell senescence
- (2019) Sonia Khemais‐Benkhiat et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- SIRT1 modulates cell cycle progression by regulating CHK2 acetylation−phosphorylation
- (2019) Wenyu Zhang et al. CELL DEATH AND DIFFERENTIATION
- Acceleration of β Cell Aging Determines Diabetes and Senolysis Improves Disease Outcomes
- (2019) Cristina Aguayo-Mazzucato et al. Cell Metabolism
- SIRT1 Activation Promotes β-Cell Regeneration by Activating Endocrine Progenitor Cells via AMPK Signaling-Mediated Fatty Acid Oxidation
- (2019) Shang Ying Wu et al. STEM CELLS
- Aging and stress induced β cell senescence and its implication in diabetes development
- (2019) Na Li et al. Aging-US
- Putting the brakes on the cell cycle: mechanisms of cellular growth arrest
- (2019) Lindsey R Pack et al. CURRENT OPINION IN CELL BIOLOGY
- 7-Ketocholesterol in disease and aging
- (2019) Amelia Anderson et al. Redox Biology
- Nuclear Genomic Instability and Aging
- (2018) Laura J. Niedernhofer et al. Annual Review of Biochemistry
- Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing
- (2018) Dominick G. A. Burton et al. BIOGERONTOLOGY
- 7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD
- (2017) Thomas Nury et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- The endoplasmic reticulum stress/autophagy pathway is involved in cholesterol-induced pancreatic β-cell injury
- (2017) Fei-Juan Kong et al. Scientific Reports
- Effects of dietary fatty acids and cholesterol excess on liver injury: A lipidomic approach
- (2016) Gaetano Serviddio et al. Redox Biology
- Implications of Genetic and Epigenetic Alterations of CDKN2A (p16 INK4a ) in Cancer
- (2016) Ran Zhao et al. EBioMedicine
- Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia
- (2015) Andreia V. Pinho et al. PLoS One
- Involvement of oxysterols in age-related diseases and ageing processes
- (2014) Amira Zarrouk et al. AGEING RESEARCH REVIEWS
- Brain peroxisomes
- (2013) D. Trompier et al. BIOCHIMIE
- Age-associated changes of islet endocrine cells and the effects of body mass index in Japanese
- (2013) Hiroki Mizukami et al. Journal of Diabetes Investigation
- Activation of SIRT1 protects pancreatic β-cells against palmitate-induced dysfunction
- (2012) Ling Wu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Liver X receptors as regulators of macrophage inflammatory and metabolic pathways
- (2010) Noelia A-González et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis
- (2009) Anne Vejux et al. MOLECULAR ASPECTS OF MEDICINE
- Cholesterol in islet dysfunction and type 2 diabetes
- (2008) Liam R. Brunham et al. JOURNAL OF CLINICAL INVESTIGATION
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