标题
Functional changes in beta cells during ageing and senescence
作者
关键词
-
出版物
DIABETOLOGIA
Volume 63, Issue 10, Pages 2022-2029
出版商
Springer Science and Business Media LLC
发表日期
2020-09-07
DOI
10.1007/s00125-020-05185-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans
- (2019) Nicole Ehrhardt et al. Obesity
- A Map of Human Type 1 Diabetes Progression by Imaging Mass Cytometry
- (2019) Nicolas Damond et al. Cell Metabolism
- Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes
- (2019) Yue J. Wang et al. Cell Metabolism
- Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes
- (2019) Peter J. Thompson et al. Cell Metabolism
- Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
- (2019) Allyson K. Palmer et al. AGING CELL
- Acceleration of β Cell Aging Determines Diabetes and Senolysis Improves Disease Outcomes
- (2019) Cristina Aguayo-Mazzucato et al. Cell Metabolism
- Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells
- (2019) Birgit Gustafson et al. Nature Communications
- Metabolic activation-driven mitochondrial hyperpolarization predicts insulin secretion in human pancreatic beta-cells
- (2018) Akos A. Gerencser BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Pancreatic β Cell Regeneration as a Possible Therapy for Diabetes
- (2018) Cristina Aguayo-Mazzucato et al. Cell Metabolism
- Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men
- (2018) Patrik Rorsman et al. PHYSIOLOGICAL REVIEWS
- Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables
- (2018) Emma Ahlqvist et al. Lancet Diabetes & Endocrinology
- Forkhead Box Protein 1 (FoxO1) Inhibits Accelerated β Cell Aging in Pancreas-specific SMAD7 Mutant Mice
- (2017) Xiangwei Xiao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty
- (2017) Michael B. Stout et al. PHYSIOLOGY
- Pancreatic β-Cells From Mice Offset Age-Associated Mitochondrial Deficiency With Reduced KATPChannel Activity
- (2016) Trillian Gregg et al. DIABETES
- Effects of Aging on Visceral and Subcutaneous Fat Areas and on Homeostasis Model Assessment of Insulin Resistance and Insulin Secretion Capacity in a Comprehensive Health Checkup
- (2016) Hiroshi Hirose et al. Journal of Atherosclerosis and Thrombosis
- p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion
- (2016) Aharon Helman et al. NATURE MEDICINE
- Aging-Dependent Demethylation of Regulatory Elements Correlates with Chromatin State and Improved β Cell Function
- (2015) Dana Avrahami et al. Cell Metabolism
- Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets
- (2015) Ksenia Tugay et al. DIABETOLOGIA
- Bioenergetic Analysis of Single Pancreatic β-Cells Indicates an Impaired Metabolic Signature in Type 2 Diabetic Subjects
- (2015) Akos A. Gerencser ENDOCRINOLOGY
- Age-Related Mitochondrial DNA Depletion and the Impact on Pancreatic Beta Cell Function
- (2014) Donna L. Nile et al. PLoS One
- Young capillary vessels rejuvenate aged pancreatic islets
- (2014) Joana Almaça et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Systemic Regulation of the Age-Related Decline of Pancreatic β-Cell Replication
- (2013) Seth J. Salpeter et al. DIABETES
- Worse Pancreatic -cell Function and Better Insulin Sensitivity in Older Chinese Without Diabetes
- (2013) J. Xiao et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- -Cell Mass and Turnover in Humans: Effects of obesity and aging
- (2012) Y. Saisho et al. DIABETES CARE
- Pancreatic Beta Cells in Very Old Mice Retain Capacity for Compensatory Proliferation
- (2012) Miri Stolovich-Rain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Formation of a Human β-Cell Population within Pancreatic Islets Is Set Early in Life
- (2012) Brigid E. Gregg et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- A Low-Oxygenated Subpopulation of Pancreatic Islets Constitutes a Functional Reserve of Endocrine Cells
- (2011) R. Olsson et al. DIABETES
- Exendin-4 Improves Blood Glucose Control in Both Young and Aging Normal Non-Diabetic Mice, Possible Contribution of Beta Cell Independent Effects
- (2011) Rongrong Fan et al. PLoS One
- Cell cycle control of β-cell replication in the prenatal and postnatal human pancreas
- (2010) Christina U. Köhler et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
- Contribution of postnatally formed small beta cell aggregates to functional beta cell mass in adult rat pancreas
- (2010) M. Chintinne et al. DIABETOLOGIA
- Age-Dependent Decline in -Cell Proliferation Restricts the Capacity of -Cell Regeneration in Mice
- (2009) S.-I. Tschen et al. DIABETES
- Adaptive -Cell Proliferation Is Severely Restricted With Advanced Age
- (2009) M. M. Rankin et al. DIABETES
- Bmi-1 regulates the Ink4a/Arf locus to control pancreatic -cell proliferation
- (2009) S. Dhawan et al. GENES & DEVELOPMENT
- Polycomb protein Ezh2 regulates pancreatic -cell Ink4a/Arf expression and regeneration in diabetes mellitus
- (2009) H. Chen et al. GENES & DEVELOPMENT
- Age-related decline in mitochondrial DNA copy number in isolated human pancreatic islets
- (2008) L. M. Cree et al. DIABETOLOGIA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now