PPAR-γ Activation Alleviates Osteoarthritis through Both the Nrf2/NLRP3 and PGC-1α/Δψm Pathways by Inhibiting Pyroptosis
出版年份 2023 全文链接
标题
PPAR-γ Activation Alleviates Osteoarthritis through Both the Nrf2/NLRP3 and PGC-1α/Δψm Pathways by Inhibiting Pyroptosis
作者
关键词
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出版物
PPAR Research
Volume 2023, Issue -, Pages 1-19
出版商
Hindawi Limited
发表日期
2023-03-28
DOI
10.1155/2023/2523536
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- PGC-1α inhibits the NLRP3 inflammasome via preserving mitochondrial viability to protect kidney fibrosis
- (2022) Bo Young Nam et al. Cell Death & Disease
- Glitazones, PPAR-γ and Neuroprotection
- (2021) Ashwini Prem Kumar et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- USP7 Inhibition Alleviates H2O2-Induced Injury in Chondrocytes via Inhibiting NOX4/NLRP3 Pathway
- (2021) Gang Liu et al. Frontiers in Pharmacology
- LncRNA GAS5 inhibits miR-579-3p to activate SIRT1/PGC-1α/Nrf2 signaling pathway to reduce cell pyroptosis in sepsis-associated renal injury
- (2021) Hua Ling et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- CY-09 attenuates the progression of osteoarthritis via inhibiting NLRP3 inflammasome-mediated pyroptosis
- (2021) Yao Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A High-Resolution Cell Atlas of the Domestic Pig Lung and an Online Platform for Exploring Lung Single-Cell Data
- (2021) Lijing Zhang et al. Journal of Genetics and Genomics
- NLRP3 inflammasome mediated pyroptosis is involved in cadmium exposure-induced neuroinflammation through the IL-1β/IkB-α-NF-κB-NLRP3 feedback loop in swine
- (2021) Jingzeng Cai et al. TOXICOLOGY
- Pioglitazone Inhibits Diabetes-Induced Atrial Mitochondrial Oxidative Stress and Improves Mitochondrial Biogenesis, Dynamics, and Function Through the PPAR-γ/PGC-1α Signaling Pathway
- (2021) Zhiwei Zhang et al. Frontiers in Pharmacology
- Vinpocetine attenuates fluoxetine-induced liver damage in rats; Role of Nrf2 and PPAR-γ
- (2021) Gellan Alaa Mohamed Kamel HUMAN & EXPERIMENTAL TOXICOLOGY
- Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response
- (2021) Lu Wang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Role of Mitochondria in Physiology of Chondrocytes and Diseases of Osteoarthritis and Rheumatoid Arthritis
- (2021) Shiyi Kan et al. Cartilage
- The advances in pyroptosis initiated by inflammasome in inflammatory and immune diseases
- (2020) Faqin Liang et al. INFLAMMATION RESEARCH
- Targeting Keap1/Nrf2/ARE signaling pathway in multiple sclerosis
- (2020) Danica Michaličková et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- LPS ‐Induced Inflammation Prior to Injury Exacerbates the Development of Post‐Traumatic Osteoarthritis in Mice
- (2020) Melanie E Mendez et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Chrysin rescues rat myocardium from ischemia-reperfusion injury via PPAR-γ/Nrf2 activation
- (2020) Neha Rani et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation
- (2020) Chiara De Nuccio et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Relationship between the pyroptosis of fibroblast‑like synoviocytes and HMGB1 secretion in knee osteoarthritis
- (2020) Yancheng Xiao et al. Molecular Medicine Reports
- Trpv4 regulates Nlrp3 inflammasome via SIRT1/PGC-1α pathway in a cuprizone-induced mouse model of demyelination
- (2020) Yanan Liu et al. EXPERIMENTAL NEUROLOGY
- Chlorpyrifos activates cell pyroptosis and increases susceptibility on oxidative stress-induced toxicity by miR-181/SIRT1/PGC-1α/Nrf2 signaling pathway in human neuroblastoma SH-SY5Y cells: Implication for association between chlorpyrifos and Parkinson's
- (2019) Meng-Wen Zhao et al. ENVIRONMENTAL TOXICOLOGY
- Neferine inhibits LPS-ATP-induced endothelial cell pyroptosis via regulation of ROS/NLRP3/Caspase-1 signaling pathway
- (2019) Yang-Shuo Tang et al. INFLAMMATION RESEARCH
- Melatonin Attenuates LPS-Induced Acute Depressive-Like Behaviors and Microglial NLRP3 Inflammasome Activation Through the SIRT1/Nrf2 Pathway
- (2019) Burak I. Arioz et al. Frontiers in Immunology
- Low dose of indomethacin and Hedgehog signaling inhibitor administration synergistically attenuates cartilage damage in osteoarthritis by controlling chondrocytes pyroptosis
- (2019) Qingbai Liu et al. GENE
- Icariin alleviates osteoarthritis by inhibiting NLRP3-mediated pyroptosis
- (2019) Yan Zu et al. Journal of Orthopaedic Surgery and Research
- Rational Design, Synthesis, and In Vitro Neuroprotective Evaluation of Novel Glitazones for PGC-1α Activation via PPAR-γ: a New Therapeutic Strategy for Neurodegenerative Disorders
- (2019) Antony Justin et al. NEUROTOXICITY RESEARCH
- Suppression of Nrf2 attenuates adipogenesis and decreases FGF21 expression through PPAR gamma in 3T3-L1 cells
- (2018) Bo-Rahm Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibition of NLRP9b attenuates acute lung injury through suppressing inflammation, apoptosis and oxidative stress in murine and cell models
- (2018) Qiu Yanling et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- NLRP1 and NLRP3 inflammasomes mediate LPS/ATP‑induced pyroptosis in knee osteoarthritis
- (2018) Ling‑Rui Zhao et al. Molecular Medicine Reports
- NLRP3 as a potentially novel biomarker for the management of osteoarthritis
- (2018) M.J. McAllister et al. OSTEOARTHRITIS AND CARTILAGE
- Homocysteine causes dysfunction of chondrocytes and oxidative stress through repression of SIRT1/AMPK pathway: A possible link between hyperhomocysteinemia and osteoarthritis
- (2018) Ching-Hou Ma et al. Redox Biology
- Catalase Enhances Viability of Human Chondrocytes in Culture by Reducing Reactive Oxygen Species and Counteracting Tumor Necrosis Factor-α-Induced Apoptosis
- (2018) Siming Li et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Die Rolle der Inflammation bei Arthroseschmerzen
- (2018) T. A. Nees et al. SCHMERZ
- Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome
- (2018) Jaye M. Platnich et al. Cell Reports
- Osteoarthritis: toward a comprehensive understanding of pathological mechanism
- (2017) Di Chen et al. Bone Research
- NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
- (2016) Zhenyu Zhong et al. CELL
- Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?
- (2015) Justine M. Abais et al. ANTIOXIDANTS & REDOX SIGNALING
- Peroxisome proliferator activated receptor-γ agonists protect oligodendrocyte progenitors against tumor necrosis factor-alpha-induced damage: Effects on mitochondrial functions and differentiation
- (2015) C. De Nuccio et al. EXPERIMENTAL NEUROLOGY
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Ligands for the Nuclear Peroxisome Proliferator-Activated Receptor Gamma
- (2015) Sascha Sauer TRENDS IN PHARMACOLOGICAL SCIENCES
- Mitochondrial Pathology in Osteoarthritic Chondrocytes
- (2014) Longhuo Wu et al. CURRENT DRUG TARGETS
- Metformin induces microRNA-34a to downregulate the Sirt1/Pgc-1α/Nrf2 pathway, leading to increased susceptibility of wild-type p53 cancer cells to oxidative stress and therapeutic agents
- (2014) Minh Truong Do et al. FREE RADICAL BIOLOGY AND MEDICINE
- Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice
- (2014) Dewei Ye et al. HEPATOLOGY
- The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
- (2014) John D. Hayes et al. TRENDS IN BIOCHEMICAL SCIENCES
- The regulation of catalase activity by PPARγis affected byα-synuclein
- (2014) Eugenia Yakunin et al. Annals of Clinical and Translational Neurology
- Genetic Activation of Nrf2 Protects against Fasting-Induced Oxidative Stress in Livers of Mice
- (2013) Yu-Kun Jennifer Zhang et al. PLoS One
- Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1-mediated interleukin-1β secretion
- (2012) Pei-Chun Liao et al. INFLAMMATION RESEARCH
- Osteochondral alterations in osteoarthritis
- (2011) Sunita Suri et al. BONE
- Double antioxidant activities of rosiglitazone against high glucose-induced oxidative stress in hepatocyte
- (2011) Xin Wang et al. TOXICOLOGY IN VITRO
- Nrf2 and PPARγ
- (2010) Raju C. Reddy et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Nrf2-regulated PPARγ Expression Is Critical to Protection against Acute Lung Injury in Mice
- (2010) Hye-Youn Cho et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the rabbit
- (2010) S. Laverty et al. OSTEOARTHRITIS AND CARTILAGE
- Peroxisome Proliferator-Activated Receptor-γ Agonists Promote Differentiation and Antioxidant Defenses of Oligodendrocyte Progenitor Cells
- (2009) Antonietta Bernardo et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
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