NLRP3 inflammasome mediated pyroptosis is involved in cadmium exposure-induced neuroinflammation through the IL-1β/IkB-α-NF-κB-NLRP3 feedback loop in swine

Cadmium induces mitophagy via AMP‐activated protein kinases activation in a PINK1/Parkin‐dependent manner in PC12 cells

(2020) Tao Wang et al.   CELL PROLIFERATION

MicroRNA profiling identifies biomarkers in head kidneys of common carp exposed to cadmium

(2020) Qi Liu et al.   CHEMOSPHERE

Cadmium exposure induces apoptosis, inflammation and immunosuppression through CYPs activation and antioxidant dysfunction in common carp neutrophils

(2020) Sun Jiaxin et al.   FISH & SHELLFISH IMMUNOLOGY

Chlorpyrifos induces the apoptosis and necroptosis of L8824 cells through the ROS/PTEN/PI3K/AKT axis

(2020) Lanqiao Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Bisphenol A regulates cytochrome P450 1B1 through miR-27b-3p and induces carp lymphocyte oxidative stress leading to apoptosis

(2020) Qingqing Liu et al.   FISH & SHELLFISH IMMUNOLOGY

Glyphosate induces lymphocyte cell dysfunction and apoptosis via regulation of miR-203 targeting of PIK3R1 in common carp (Cyprinus carpio L.)

(2020) Wei Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Role of pyroptosis in liver diseases

(2020) Abdullah Al Mamun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cadmium exposure induces pyroptosis of lymphocytes in carp pronephros and spleens by activating NLRP3

(2020) Yiming Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Zinc application alleviates the adverse renal effects of arsenic stress in a protein quality control way in common carp

(2020) Yu Wang et al.   ENVIRONMENTAL RESEARCH

Antagonistic effect of VDR/CREB1 pathway on cadmium-induced apoptosis in porcine spleen

(2020) Zhang Yiming et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Human Lung Cell Pyroptosis Following Traumatic Brain Injury

(2019) Nadine Kerr et al.   Cells

Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

(2019) Yang Yang et al.   Cell Death & Disease

Cadmium level in brain correlates with memory impairment in F1 and F2 generation mice: improvement with quercetin

(2019) Sumita Halder et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Earthworms and cadmium – Heavy metal resistant gut bacteria as indicators for heavy metal pollution in soils?

(2019) Maja Šrut et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Inflammasomes in neuroinflammatory and neurodegenerative diseases

(2019) Sofie Voet et al.   EMBO Molecular Medicine

H2S inhalation-induced energy metabolism disturbance is involved in LPS mediated hepatocyte apoptosis through mitochondrial pathway

(2019) Jinming Guo et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Induction of Neuroinflammation and Neurotoxicity by Synthetic Hemozoin

(2019) Ravikanth Velagapudi et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The relative impact of toxic heavy metals (THMs) (arsenic (As), cadmium (Cd), chromium (Cr)(VI), mercury (Hg), and lead (Pb)) on the total environment: an overview

(2019) Zeeshanur Rahman et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Trehalose suppresses cadmium-activated Nrf2 signaling pathway to protect against spleen injury

(2019) Kui-Chao Qu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Di-(2-ethyl hexyl) phthalate induces necroptosis in chicken cardiomyocytes by triggering calcium overload

(2019) Yingying Zheng et al.   JOURNAL OF HAZARDOUS MATERIALS

Targeting the miR-122/PKM2 autophagy axis relieves arsenic stress

(2019) Yu Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Application of transcriptome analysis: Oxidative stress, inflammation and microtubule activity disorder caused by ammonia exposure may be the primary factors of intestinal microvilli deficiency in chicken

(2019) Shengchen Wang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

NEK7 interacts with NLRP3 to modulate the pyroptosis in inflammatory bowel disease via NF-κB signaling

(2019) Xueliang Chen et al.   Cell Death & Disease

lnc-3215 Suppression Leads to Calcium Overload in Selenium Deficiency-Induced Chicken Heart Lesion via the lnc-3215-miR-1594-TNN2 Pathway

(2019) Jie Yang et al.   Molecular Therapy-Nucleic Acids

Inhibition of TRAF6 ubiquitin-ligase activity by PRDX1 leads to inhibition of NFKB activation and autophagy activation

(2018) Yoon Min et al.   Autophagy

TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis

(2018) Jing Fang et al.   Cell Reports

Inflammatory caspase-related pyroptosis: mechanism, regulation and therapeutic potential for inflammatory bowel disease

(2018) Yuan-Yuan Yuan et al.   Gastroenterology Report

Toxicity of cadmium and zinc to small soil protists

(2018) Jesper Liengaard Johansen et al.   ENVIRONMENTAL POLLUTION

The role of mitochondria in NLRP3 inflammasome activation

(2018) Qiuyun Liu et al.   MOLECULAR IMMUNOLOGY

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

(2018) Zhenyu Zhong et al.   NATURE

NF-κB-Gasdermin D (GSDMD) Axis Couples Oxidative Stress and NACHT, LRR and PYD Domains-Containing Protein 3 (NLRP3) Inflammasome-Mediated Cardiomyocyte Pyroptosis Following Myocardial Infarction

(2018) Qian Lei et al.   MEDICAL SCIENCE MONITOR

Puerarin reverses cadmium-induced lysosomal dysfunction in primary rat proximal tubular cells via inhibiting Nrf2 pathway

(2018) Li-Yuan Wang et al.   BIOCHEMICAL PHARMACOLOGY

Role of pyroptosis in cardiovascular disease

(2018) Zeng Zhaolin et al.   CELL PROLIFERATION

Effects of sevoflurane on NF-кB and TNF-α expression in renal ischemia–reperfusion diabetic rats

(2017) Yu Zhang et al.   INFLAMMATION RESEARCH

FBXO32 activates NF-κB through IκBα degradation in inflammatory and genotoxic stress

(2017) Sachin N. Meshram et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte

(2017) Letizia Mezzasoma et al.   MEDIATORS OF INFLAMMATION

Toxicity of cadmium and its health risks from leafy vegetable consumption

(2017) Yingying Huang et al.   Food & Function

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

(2016) Zhenyu Zhong et al.   CELL

Cadmium induces NLRP3 inflammasome-dependent pyroptosis in vascular endothelial cells

(2016) Haiyan Chen et al.   TOXICOLOGY LETTERS

Mechanism of NLRP3 inflammasome activation

(2014) Fayyaz S. Sutterwala et al.   Annals of the New York Academy of Sciences

Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome

(2014) Tiffany Horng   TRENDS IN IMMUNOLOGY

Expression pattern of NLRP3 and its related cytokines in the lung and brain of avian influenza virus H9N2 infected BALB/c mice

(2014) Meng Yu et al.   Virology Journal

Cellular mechanisms of cadmium-induced toxicity: a review

(2013) Anju Rani et al.   INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH

NF-κB Signaling Pathways

(2012) Stefka Mincheva-Tasheva et al.   NEUROSCIENTIST

Nervous system effects of dissolved and nanoparticulate cadmium in rats in subacute exposure

(2011) Edina Horváth et al.   JOURNAL OF APPLIED TOXICOLOGY

Current status of cadmium as an environmental health problem

(2009) Lars Järup et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Historical perspectives on cadmium toxicology

(2009) Gunnar F. Nordberg   TOXICOLOGY AND APPLIED PHARMACOLOGY

In vitro assessment of the effects of cadmium and zinc on mammalian nerve fibres

(2008) Magdalini Moschou et al.   CHEMOSPHERE