Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer
出版年份 2023 全文链接
标题
Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer
作者
关键词
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出版物
Science Translational Medicine
Volume 15, Issue 694, Pages -
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2023-05-04
DOI
10.1126/scitranslmed.adf1128
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer
- (2023) Mengdie Wang et al. Science Translational Medicine
- Role of Neuropilin-2-mediated signaling axis in cancer progression and therapy resistance
- (2022) Ridwan Islam et al. CANCER AND METASTASIS REVIEWS
- Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistance
- (2022) Ridwan Islam et al. Cell Reports
- A nanotherapeutic strategy to overcome chemotherapeutic resistance of cancer stem-like cells
- (2021) Shiyang Shen et al. Nature Nanotechnology
- N2E4, a Monoclonal Antibody Targeting Neuropilin-2, Inhibits Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma via Suppressing FAK/Erk/HIF-1α Signaling
- (2021) Li Wang et al. Frontiers in Oncology
- Integrated Chromatin Accessibility and Transcriptome Landscapes of Doxorubicin-Resistant Breast Cancer Cells
- (2021) Xuelong Wang et al. Frontiers in Cell and Developmental Biology
- Bevacizumab improves tumor infiltration of mature dendritic cells and effector T-cells in triple-negative breast cancer patients
- (2021) Yves Boucher et al. npj Precision Oncology
- Linking NRP2 With EMT and Chemoradioresistance in Bladder Cancer
- (2020) Alexander Schulz et al. Frontiers in Oncology
- Translational control of breast cancer plasticity
- (2020) Michael Jewer et al. Nature Communications
- Triple‑negative breast cancer therapy: Current and future perspectives (Review)
- (2020) Kwang‑Ai Won et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk
- (2020) Deguang Kong et al. ONCOGENE
- VEGF/Neuropilin Signaling in Cancer Stem Cells
- (2019) Arthur Mercurio INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The VEGF receptor neuropilin 2 promotes homologous recombination by stimulating YAP/TAZ-mediated Rad51 expression
- (2019) Ameer L. Elaimy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GREIN: An Interactive Web Platform for Re-analyzing GEO RNA-seq Data
- (2019) Naim Al Mahi et al. Scientific Reports
- Cancer stem cells in triple-negative breast cancer: a potential target and prognostic marker
- (2018) Christopher J O'Conor et al. Biomarkers in Medicine
- Cancer stem cell in breast cancer therapeutic resistance
- (2018) Xupeng Bai et al. CANCER TREATMENT REVIEWS
- A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity
- (2018) Norman Sachs et al. CELL
- Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
- (2018) Aurélie S. Cazet et al. Nature Communications
- DNA Methylation Profiling of Breast Cancer Cell Lines along the Epithelial Mesenchymal Spectrum—Implications for the Choice of Circulating Tumour DNA Methylation Markers
- (2018) Anh Le et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- VEGF–neuropilin-2 signaling promotes stem-like traits in breast cancer cells by TAZ-mediated repression of the Rac GAP β2-chimaerin
- (2018) Ameer L. Elaimy et al. Science Signaling
- Convergence of VEGF and YAP/TAZ signaling: Implications for angiogenesis and cancer biology
- (2018) Ameer L. Elaimy et al. Science Signaling
- Tumor Control Index as a new tool to assess tumor growth in experimental animals
- (2017) William L. Corwin et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Revisiting the Role of Bevacizumab in the Treatment of Breast Cancer
- (2017) Leticia Varella et al. SEMINARS IN ONCOLOGY
- Inflammation Triggers Zeb1-Dependent Escape from Tumor Latency
- (2016) Jasmine M. De Cock et al. CANCER RESEARCH
- Organoids: A historical perspective of thinking in three dimensions
- (2016) Marina Simian et al. JOURNAL OF CELL BIOLOGY
- Early dissemination seeds metastasis in breast cancer
- (2016) Hedayatollah Hosseini et al. NATURE
- Mechanism of early dissemination and metastasis in Her2+ mammary cancer
- (2016) Kathryn L. Harper et al. NATURE
- Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease
- (2016) Giampaolo Bianchini et al. Nature Reviews Clinical Oncology
- Targeting the VEGF-C/VEGFR3 axis suppresses Slug-mediated cancer metastasis and stemness via inhibition of KRAS/YAP1 signaling
- (2016) Yu-Wen Yeh et al. Oncotarget
- P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer
- (2016) Hira Lal Goel et al. Cell Reports
- Comparison of Clinicopathological Features and Prognosis in Triple-Negative and Non-Triple Negative Breast Cancer
- (2016) Jingdan Qiu et al. Journal of Cancer
- ZEB1: At the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance
- (2015) Peijing Zhang et al. CELL CYCLE
- The Epithelial-Mesenchymal Transition and Cancer Stem Cells: Functional and Mechanistic Links
- (2015) Xiangqiang Liu et al. CURRENT PHARMACEUTICAL DESIGN
- VEGF-C inhibition reverses resistance of bladder cancer cells to cisplatin via upregulating maspin
- (2015) HAIPENG ZHU et al. Molecular Medicine Reports
- Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form
- (2015) Matthew W. Parker et al. STRUCTURE
- Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo
- (2015) Hironao Nakayama et al. Scientific Reports
- Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity
- (2015) Gerald J Prud'homme et al. Oncotarget
- A Phase Ib study evaluating MNRP1685A, a fully human anti-NRP1 monoclonal antibody, in combination with bevacizumab and paclitaxel in patients with advanced solid tumors
- (2014) Amita Patnaik et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Neuropilin-2 Is Upregulated in Lung Cancer Cells during TGF- 1-Induced Epithelial-Mesenchymal Transition
- (2013) P. Nasarre et al. CANCER RESEARCH
- Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity
- (2013) Christine L. Chaffer et al. CELL
- Targeting Placental Growth Factor/Neuropilin 1 Pathway Inhibits Growth and Spread of Medulloblastoma
- (2013) Matija Snuderl et al. CELL
- GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation
- (2013) Hira Lal Goel et al. EMBO Molecular Medicine
- Neuropilin-1Stimulates Tumor Growth by Increasing Fibronectin Fibril Assembly in the Tumor Microenvironment
- (2012) Usman Yaqoob et al. CANCER RESEARCH
- Tumour growth inhibition and anti-metastatic activity of a mutated furin-resistant Semaphorin 3E isoform
- (2012) Andrea Casazza et al. EMBO Molecular Medicine
- Bevacizumab and breast cancer: what does the future hold?
- (2012) Christina E Stevenson et al. Future Oncology
- Structural Basis for Selective Vascular Endothelial Growth Factor-A (VEGF-A) Binding to Neuropilin-1
- (2012) Matthew W. Parker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuropilin-2 regulates 6 1 integrin in the formation of focal adhesions and signaling
- (2012) H. L. Goel et al. JOURNAL OF CELL SCIENCE
- Avastin Saga Reveals Debate Over Clinical Trial Endpoints
- (2012) S. P. Sharma JNCI-Journal of the National Cancer Institute
- Overview of theCCP4 suite and current developments
- (2011) Martyn D. Winn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Neuropilin-2 mediates VEGF-C–induced lymphatic sprouting together with VEGFR3
- (2010) Yunling Xu et al. JOURNAL OF CELL BIOLOGY
- A Mutated Soluble Neuropilin-2 B Domain Antagonizes Vascular Endothelial Growth Factor Bioactivity and Inhibits Tumor Progression
- (2010) E. Geretti et al. MOLECULAR CANCER RESEARCH
- Neuropilin-2 expression in breast cancer: correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression
- (2009) Hironao Yasuoka et al. BMC CANCER
- ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
- (2009) Yifang Hu et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Blocking Neuropilin-2 Function Inhibits Tumor Cell Metastasis
- (2008) Maresa Caunt et al. CANCER CELL
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