标题
Voltage gated sodium channels as drug discovery targets
作者
关键词
-
出版物
Channels
Volume 9, Issue 6, Pages 360-366
出版商
Informa UK Limited
发表日期
2015-12-09
DOI
10.1080/19336950.2015.1079674
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Discovery and Optimization of Selective Nav1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain
- (2015) Sharan K. Bagal et al. ACS Medicinal Chemistry Letters
- Recent progress in sodium channel modulators for pain
- (2014) Sharan K. Bagal et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism
- (2014) C. Bagneris et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gain-of-Function Mutations in SCN11A Cause Familial Episodic Pain
- (2013) Xiang Yang Zhang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Two Alternative Conformations of a Voltage-Gated Sodium Channel
- (2013) Ching-Ju Tsai et al. JOURNAL OF MOLECULAR BIOLOGY
- Structure of a Prokaryotic Sodium Channel Pore Reveals Essential Gating Elements and an Outer Ion Binding Site Common to Eukaryotic Channels
- (2013) David Shaya et al. JOURNAL OF MOLECULAR BIOLOGY
- A de novo gain-of-function mutation in SCN11A causes loss of pain perception
- (2013) Enrico Leipold et al. NATURE GENETICS
- Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels
- (2013) K. McCormack et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of the C-terminal domain in the structure and function of tetrameric sodium channels
- (2013) Claire Bagnéris et al. Nature Communications
- Advances in Targeting Voltage-Gated Sodium Channels with Small Molecules
- (2012) Antonio Nardi et al. ChemMedChem
- Voltage-Gated Sodium Channel Blockers for the Treatment of Chronic Pain
- (2012) Mark Matulenko et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Ion Channels as Therapeutic Targets: A Drug Discovery Perspective
- (2012) Sharan K. Bagal et al. JOURNAL OF MEDICINAL CHEMISTRY
- Gain-of-function Nav1.8 mutations in painful neuropathy
- (2012) C. G. Faber et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a Potent, State-Dependent Inhibitor of Nav1.7 with Oral Efficacy in the Formalin Model of Persistent Pain
- (2011) Howard Bregman et al. JOURNAL OF MEDICINAL CHEMISTRY
- The crystal structure of a voltage-gated sodium channel
- (2011) Jian Payandeh et al. NATURE
- Treatment of Nav1.7-mediated pain in inherited erythromelalgia using a novel sodium channel blocker
- (2011) Yigal Paul Goldberg et al. PAIN
- Isoform-selective voltage-gated Na+channel modulators as next-generation analgesics
- (2010) Steve England et al. Future Medicinal Chemistry
- The Tarantula Toxins ProTx-II and Huwentoxin-IV Differentially Interact with Human Nav1.7 Voltage Sensors to Inhibit Channel Activation and Inactivation
- (2010) Y. Xiao et al. MOLECULAR PHARMACOLOGY
- Subtype-selective targeting of voltage-gated sodium channels
- (2009) Steve England et al. BRITISH JOURNAL OF PHARMACOLOGY
- Sodium channel blockers for the treatment of neuropathic pain
- (2009) Anindya Bhattacharya et al. Neurotherapeutics
- Voltage-gated sodium channels: the search for subtype-selective analgesics
- (2008) Steve England EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Differential Block of Sensory Neuronal Voltage-Gated Sodium Channels by Lacosamide [(2R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide], Lidocaine, and Carbamazepine
- (2008) P. L. Sheets et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Mutation of sodium channel SCN3A in a patient with cryptogenic pediatric partial epilepsy
- (2008) Katherine D. Holland et al. NEUROSCIENCE LETTERS
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