A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection

ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response

(2021) Cheng Wang et al.   Cell Stem Cell

Neuroinvasion of SARS-CoV-2 in human and mouse brain

(2021) Eric Song et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Modeling human adaptive immune responses with tonsil organoids

(2021) Lisa E. Wagar et al.   NATURE MEDICINE

Revealing Tissue-Specific SARS-CoV-2 Infection and Host Responses using Human Stem Cell-Derived Lung and Cerebral Organoids

(2021) Shashi Kant Tiwari et al.   Stem Cell Reports

SARS-CoV-2 Infects Human Pluripotent Stem Cell-Derived Cardiomyocytes, Impairing Electrical and Mechanical Function

(2021) Silvia Marchiano et al.   Stem Cell Reports

BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection

(2021) Richard J. Mills et al.   CELL

SARS-CoV-2 Infection Induces Beta Cell Transdifferentiation

(2021) Xuming Tang et al.   Cell Metabolism

SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes

(2021) Yize Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19

(2021) Juan A. Perez-Bermejo et al.   Science Translational Medicine

SARS-CoV-2 targets glial cells in human cortical organoids

(2021) Courtney L. McMahon et al.   Stem Cell Reports

The interferon landscape along the respiratory tract impacts the severity of COVID-19

(2021) Benedetta Sposito et al.   CELL

The NF-κB transcriptional footprint is essential for SARS-CoV-2 replication

(2021) Benjamin E. Nilsson-Payant et al.   JOURNAL OF VIROLOGY

An isoform of Dicer protects mammalian stem cells against multiple RNA viruses

(2021) Enzo Z. Poirier et al.   SCIENCE

A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

(2021) Joep Beumer et al.   Nature Communications

Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2

(2021) Liuliu Yang et al.   Stem Cell Reports

The New Generation hDHODH Inhibitor MEDS433 Hinders the In Vitro Replication of SARS-CoV-2 and Other Human Coronaviruses

(2021) Arianna Calistri et al.   Microorganisms

The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells

(2021) Xiaodong Zhuang et al.   iScience

Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors

(2021) Sarah Huff et al.   JOURNAL OF MEDICINAL CHEMISTRY

An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection

(2021) Xiaohua Duan et al.   Cell Reports

Effect of SARS-CoV-2 proteins on vascular permeability

(2021) Rossana Rauti et al.   eLife

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

(2020) Carly G.K. Ziegler et al.   CELL

Identification of the Repressive Domain of the Negative Circadian Clock Component CHRONO

(2020) Yu Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

(2020) Liuliu Yang et al.   Cell Stem Cell

SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes

(2020) Denisa Bojkova et al.   CARDIOVASCULAR RESEARCH

Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium

(2020) Fadi Jacob et al.   Cell Stem Cell

Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Platform to Study SARS-CoV-2 Related Myocardial Injury

(2020) Chun-Ka Wong et al.   CIRCULATION JOURNAL

Cholesterol 25‐Hydroxylase inhibits SARS ‐CoV‐2 and other coronaviruses by depleting membrane cholesterol

(2020) Shaobo Wang et al.   EMBO JOURNAL

Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

(2020) Ryan M. Samuel et al.   Cell Stem Cell

A molecular cell atlas of the human lung from single-cell RNA sequencing

(2020) Kyle J. Travaglini et al.   NATURE

Host metabolism dysregulation and cell tropism identification in human airway and alveolar organoids upon SARS-CoV-2 infection

(2020) Rongjuan Pei et al.   Protein & Cell

Therapeutic modulation of retinoid X receptors – SAR and therapeutic potential of RXR ligands and recent patents

(2019) Simone Schierle et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors

(2018) Laleh Haghverdi et al.   NATURE BIOTECHNOLOGY

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Gene Model 129 (Gm129) Encodes a Novel Transcriptional Repressor That Modulates Circadian Gene Expression

(2014) Yunus Annayev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Machine Learning Helps Identify CHRONO as a Circadian Clock Component

(2014) Ron C. Anafi et al.   PLOS BIOLOGY

Efficient generation of lung and airway epithelial cells from human pluripotent stem cells

(2013) Sarah X L Huang et al.   NATURE BIOTECHNOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions

(2012) Xiaojun Lian et al.   Nature Protocols

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY