标题
Clinical Trial Design for Triglyceride-Rich Lipoprotein-Lowering Therapies
作者
关键词
-
出版物
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Volume 81, Issue 16, Pages 1646-1658
出版商
Elsevier BV
发表日期
2023-04-18
DOI
10.1016/j.jacc.2023.02.034
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Effect of Vupanorsen on Non–High-Density Lipoprotein Cholesterol Levels in Statin-Treated Patients With Elevated Cholesterol: TRANSLATE-TIMI 70
- (2022) Brian A. Bergmark et al. CIRCULATION
- A Biological Rationale for the Disparate Effects of Omega-3 Fatty Acids on Cardiovascular Disease Outcomes
- (2022) Samuel C.R. Sherratt et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Effects of Randomized Treatment With Icosapent Ethyl and a Mineral Oil Comparator on Interleukin-1β, Interleukin-6, C-Reactive Protein, Oxidized Low-Density Lipoprotein Cholesterol, Homocysteine, Lipoprotein(a), and Lipoprotein-Associated Phospholipase A2: A REDUCE-IT Biomarker Substudy
- (2022) Paul M Ridker et al. CIRCULATION
- Evinacumab reduces remnant cholesterol in patients with hypercholesterolemia or hypertriglyceridemia
- (2022) R.S. Rosenson et al. ATHEROSCLEROSIS
- Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk
- (2022) Aruna Das Pradhan et al. NEW ENGLAND JOURNAL OF MEDICINE
- ANGPTL3 Inhibition With Evinacumab Results in Faster Clearance of IDL and LDL apoB in Patients With Homozygous Familial Hypercholesterolemia
- (2021) Laurens F. Reeskamp et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Genetics of Triglyceride-Rich Lipoproteins Guide Identification of Pharmacotherapy for Cardiovascular Risk Reduction
- (2021) Aleesha Shaik et al. CARDIOVASCULAR DRUGS AND THERAPY
- Per-Particle Triglyceride-Rich Lipoproteins Imply Higher Myocardial Infarction Risk Than Low-Density Lipoproteins
- (2021) Mia Ø. Johansen et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial
- (2021) Ioanna Gouni-Berthold et al. Lancet Diabetes & Endocrinology
- Remnant cholesterol predicts cardiovascular disease beyond LDL and ApoB: a primary prevention study
- (2021) Renato Quispe et al. EUROPEAN HEART JOURNAL
- Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus statement from the European Atherosclerosis Society
- (2021) Henry N Ginsberg et al. EUROPEAN HEART JOURNAL
- Directly measured vs. calculated remnant cholesterol identifies additional overlooked individuals in the general population at higher risk of myocardial infarction
- (2021) Anette Varbo et al. EUROPEAN HEART JOURNAL
- Inhibition of Angiopoietin-Like Protein 3 With Evinacumab in Subjects With High and Severe Hypertriglyceridemia
- (2021) Zahid Ahmad et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- 2021 ACC Expert Consensus Decision Pathway on the Management of ASCVD Risk Reduction in Patients With Persistent Hypertriglyceridemia
- (2021) Salim S. Virani et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- The association of triglyceride levels with the incidence of initial and recurrent acute pancreatitis
- (2021) Robert J. Sanchez et al. Lipids in Health and Disease
- New Therapies for Lowering Triglyceride-Rich Lipoproteins
- (2021) Robert S. Rosenson et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Angiopoietin-like protein 3 (ANGPTL3) governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance
- (2020) Rene C. Adam et al. JOURNAL OF LIPID RESEARCH
- The Roles of ApoC-III on the Metabolism of Triglyceride-Rich Lipoproteins in Humans
- (2020) Jan Borén et al. Frontiers in Endocrinology
- Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia
- (2020) Daniel Gaudet et al. EUROPEAN HEART JOURNAL
- Evinacumab for Homozygous Familial Hypercholesterolemia
- (2020) Frederick J. Raal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Triglyceride-Rich Lipoprotein Remnants and Cardiovascular Disease
- (2020) Edward K Duran et al. CLINICAL CHEMISTRY
- Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk
- (2020) Stephen J. Nicholls et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Evinacumab in Patients with Refractory Hypercholesterolemia
- (2020) Robert S. Rosenson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Association of Triglyceride-Lowering LPL Variants and LDL-C–Lowering LDLR Variants With Risk of Coronary Heart Disease
- (2019) Brian A. Ference et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levels
- (2019) Veronica J Alexander et al. EUROPEAN HEART JOURNAL
- Inhibition of Angiopoietin-Like Protein 3 With a Monoclonal Antibody Reduces Triglycerides in Hypertriglyceridemia
- (2019) Zahid Ahmad et al. CIRCULATION
- 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk
- (2019) François Mach et al. EUROPEAN HEART JOURNAL
- Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome
- (2019) Joseph L. Witztum et al. NEW ENGLAND JOURNAL OF MEDICINE
- APOC3Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular RiskHighlights
- (2018) Anders B. Wulff et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Triglyceride-Rich Lipoprotein Cholesterol and Risk of Cardiovascular Events Among Patients Receiving Statin Therapy in the Treating to New Targets (TNT) Trial
- (2018) Antonio J. Vallejo-Vaz et al. CIRCULATION
- Impact of Lipids on Cardiovascular Health
- (2018) Brian A. Ference et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus
- (2018) NEW ENGLAND JOURNAL OF MEDICINE
- Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer
- (2018) JoAnn E. Manson et al. NEW ENGLAND JOURNAL OF MEDICINE
- FISHing for the Miracle of Eicosapentaenoic Acid
- (2018) John J.P. Kastelein et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia
- (2018) Deepak L. Bhatt et al. NEW ENGLAND JOURNAL OF MEDICINE
- ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance
- (2017) Jorge F. Haller et al. JOURNAL OF LIPID RESEARCH
- ANGPTL3 Deficiency and Protection Against Coronary Artery Disease
- (2017) Nathan O. Stitziel et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease
- (2017) Frederick E. Dewey et al. NEW ENGLAND JOURNAL OF MEDICINE
- Triglyceride-Rich Lipoproteins and Atherosclerotic Cardiovascular Disease
- (2016) Børge G. Nordestgaard CIRCULATION RESEARCH
- Apolipoprotein CIII is a new player in diabetes
- (2016) Lisa Juntti-Berggren et al. CURRENT OPINION IN LIPIDOLOGY
- Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease
- (2016) Anna Helgadottir et al. NATURE GENETICS
- Nonfasting Mild-to-Moderate Hypertriglyceridemia and Risk of Acute Pancreatitis
- (2016) Simon B. Pedersen et al. JAMA Internal Medicine
- Minireview: Roles of Fibroblast Growth Factors 19 and 21 in Metabolic Regulation and Chronic Diseases
- (2015) Fangfang Zhang et al. MOLECULAR ENDOCRINOLOGY
- Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia
- (2015) Daniel Gaudet et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genetics and Causality of Triglyceride-Rich Lipoproteins in Atherosclerotic Cardiovascular Disease
- (2014) Robert S. Rosenson et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease
- (2014) Anders Berg Jørgensen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting APOC3 in the Familial Chylomicronemia Syndrome
- (2014) Daniel Gaudet et al. NEW ENGLAND JOURNAL OF MEDICINE
- Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease
- (2014) NEW ENGLAND JOURNAL OF MEDICINE
- Association Between Plasma Triglycerides and High-Density Lipoprotein Cholesterol and Microvascular Kidney Disease and Retinopathy in Type 2 Diabetes Mellitus
- (2013) Frank M. Sacks et al. CIRCULATION
- Apolipoproteins C-I and C-III Inhibit Lipoprotein Lipase Activity by Displacement of the Enzyme from Lipid Droplets
- (2013) Mikael Larsson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Common variants associated with plasma triglycerides and risk for coronary artery disease
- (2013) Ron Do et al. NATURE GENETICS
- Determinants of Residual Risk in Secondary Prevention Patients Treated With High- Versus Low-Dose Statin Therapy
- (2012) Samia Mora et al. CIRCULATION
- Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management
- (2011) M. John Chapman et al. EUROPEAN HEART JOURNAL
- Apolipoprotein C-III and the Metabolic Basis for Hypertriglyceridemia and the Dense Low-Density Lipoprotein Phenotype
- (2010) Chunyu Zheng et al. CIRCULATION
- Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis
- (2010) Min Jun et al. LANCET
- Exome Sequencing,ANGPTL3Mutations, and Familial Combined Hypolipidemia
- (2010) Kiran Musunuru et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus
- (2010) NEW ENGLAND JOURNAL OF MEDICINE
- A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection
- (2008) T. I. Pollin et al. SCIENCE
- Triglycerides and cardiovascular events in ACS: the need for combined lipid-altering therapies
- (2008) Robert S Rosenson et al. Nature clinical practice. Cardiovascular medicine
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