Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

Dietary monounsaturated fat activates metabolic pathways for triglyceride-rich lipoproteins that involve apolipoproteins E and C-III

(2018) Chunyu Zheng et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult – 2009 recommendations

(2011) Jacques Genest et al.   CANADIAN JOURNAL OF CARDIOLOGY

HDL Measures, Particle Heterogeneity, Proposed Nomenclature, and Relation to Atherosclerotic Cardiovascular Events

(2011) R. S. Rosenson et al.   CLINICAL CHEMISTRY

Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

(2011) Amit V. Khera et al.   NEW ENGLAND JOURNAL OF MEDICINE

High-Density Lipoprotein Function in Regulating Insulin Secretion: Possible Relevance to Metabolic Syndrome

(2010) Godfrey S. Getz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cholesterol Efflux Potential and Antiinflammatory Properties of High-Density Lipoprotein After Treatment With Niacin or Anacetrapib

(2010) Laurent Yvan-Charvet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effects of High-Density Lipoproteins on Pancreatic β-Cell Insulin Secretion

(2010) Michelle A. Fryirs et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Evidence That Niacin Inhibits Acute Vascular Inflammation and Improves Endothelial Dysfunction Independent of Changes in Plasma Lipids

(2010) Ben J. Wu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

GPIHBP1: Lipoprotein Lipase's Ticket to Ride

(2010) Edward A. Fisher   Cell Metabolism

Novel drugs in familial combined hyperlipidemia: lessons from type 2 diabetes mellitus

(2010) Martijn CGJ Brouwers et al.   CURRENT OPINION IN LIPIDOLOGY

Non-LDL-related dyslipidaemia and coronary risk: a case-control study

(2010) Gerd Assmann et al.   Diabetes & Vascular Disease Research

Ability of traditional lipid ratios and apolipoprotein ratios to predict cardiovascular risk in people with type 2 diabetes

(2010) M.-R. Taskinen et al.   DIABETOLOGIA

Effects of fenofibrate on renal function in patients with type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study

(2010) T. M. E. Davis et al.   DIABETOLOGIA

Safety and tolerability of dalcetrapib (RO4607381/JTT-705): results from a 48-week trial

(2010) Evan A. Stein et al.   EUROPEAN HEART JOURNAL

Lipoprotein(a) as a cardiovascular risk factor: current status

(2010) Børge G. Nordestgaard et al.   EUROPEAN HEART JOURNAL

Blood lipids in 75,048 type 2 diabetic patients: a population-based survey from the Swedish National diabetes register

(2010) Mats Eriksson et al.   EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION

Dalcetrapib: a review of Phase II data

(2010) Jennifer G Robinson   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Dyslipidaemia in the metabolic syndrome and type 2 diabetes: pathogenesis, priorities, pharmacotherapies

(2010) Dick C Chan et al.   EXPERT OPINION ON PHARMACOTHERAPY

Linkage and association analyses identify a candidate region for apoB level on chromosome 4q32.3 in FCHL families

(2010) Ellen M. Wijsman et al.   HUMAN GENETICS

Efficacy and safety of extended-release niacin/laropiprant plus statin vs. doubling the dose of statin in patients with primary hypercholesterolaemia or mixed dyslipidaemia

(2010) S. Shah et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

The HDL hypothesis: does high-density lipoprotein protect from atherosclerosis?: Fig. 1.

(2010) Menno Vergeer et al.   JOURNAL OF LIPID RESEARCH

HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial

(2010) Paul M Ridker et al.   LANCET

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

(2010)   LANCET

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

(2010)   LANCET

Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis

(2010) Min Jun et al.   LANCET

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

(2010) Christopher T Johansen et al.   NATURE GENETICS

Combination Lipid Therapy in Type 2 Diabetes

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Safety of Anacetrapib in Patients with or at High Risk for Coronary Heart Disease

(2010) Christopher P. Cannon et al.   NEW ENGLAND JOURNAL OF MEDICINE

n–3 Fatty Acids and Cardiovascular Events after Myocardial Infarction

(2010) Daan Kromhout et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Medical Therapies on Retinopathy Progression in Type 2 Diabetes

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Niacin and fibrates in atherogenic dyslipidemia: Pharmacotherapy to reduce cardiovascular risk

(2010) M. John Chapman et al.   PHARMACOLOGY & THERAPEUTICS

Plasma Triglycerides and Cardiovascular Events in the Treating to New Targets and Incremental Decrease in End-Points Through Aggressive Lipid Lowering Trials of Statins in Patients With Coronary Artery Disease

(2009) Ole Faergeman et al.   AMERICAN JOURNAL OF CARDIOLOGY

Evaluating the Incremental Benefits of Raising High-Density Lipoprotein Cholesterol Levels During Lipid Therapy After Adjustment for the Reductions in Other Blood Lipid Levels

(2009) Steven A. Grover et al.   ARCHIVES OF INTERNAL MEDICINE

Relationships of HDL Cholesterol, ApoA-I, and ApoA-II With Homocysteine and Creatinine in Patients With Type 2 Diabetes Treated With Fenofibrate

(2009) Marja-Riitta Taskinen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Apolipoprotein A-I and Its Role in Lymphocyte Cholesterol Homeostasis and Autoimmunity

(2009) Ashley J. Wilhelm et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Chylomicronemia Elicits Atherosclerosis in Mice—Brief Report

(2009) Michael M. Weinstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Triglyceride-Rich Lipoproteins and Plasma Lipid Transport

(2009) Richard J. Havel   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genetic variation in the ABCA1 gene, HDL cholesterol, and risk of ischemic heart disease in the general population

(2009) Ruth Frikke-Schmidt   ATHEROSCLEROSIS

Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis

(2009) Eric Bruckert et al.   ATHEROSCLEROSIS

Reconstituted High-Density Lipoprotein Attenuates Platelet Function in Individuals With Type 2 Diabetes Mellitus by Promoting Cholesterol Efflux

(2009) Anna C. Calkin et al.   CIRCULATION

Endothelial-Vasoprotective Effects of High-Density Lipoprotein Are Impaired in Patients With Type 2 Diabetes Mellitus but Are Improved After Extended-Release Niacin Therapy

(2009) Sajoscha A. Sorrentino et al.   CIRCULATION

High-Density Lipoprotein Transport Through Aortic Endothelial Cells Involves Scavenger Receptor BI and ATP-Binding Cassette Transporter G1

(2009) Lucia Rohrer et al.   CIRCULATION RESEARCH

Does elevated C-reactive protein cause human atherothrombosis? Novel insights from genetics, intervention trials, and elsewhere

(2009) Børge G Nordestgaard   CURRENT OPINION IN LIPIDOLOGY

Regulatory Effects of Fenofibrate and Atorvastatin on Lipoprotein A-I and Lipoprotein A-I:A-II Kinetics in the Metabolic Syndrome

(2009) D. C. Chan et al.   DIABETES CARE

Effects of Long-Term Fenofibrate Treatment on Markers of Renal Function in Type 2 Diabetes: The FIELD Helsinki substudy

(2009) C. Forsblom et al.   DIABETES CARE

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Adaptations to exercise training within skeletal muscle in adults with type 2 diabetes or impaired glucose tolerance: a systematic review

(2009) Yi Wang et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Low- and High-Density Lipoproteins Modulate Function, Apoptosis, and Proliferation of Primary Human and Murine Pancreatic β-Cells

(2009) Sabine Rütti et al.   ENDOCRINOLOGY

Torcetrapib Induces Aldosterone and Cortisol Production by an Intracellular Calcium-Mediated Mechanism Independently of Cholesteryl Ester Transfer Protein Inhibition

(2009) Xiao Hu et al.   ENDOCRINOLOGY

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors

(2009) M. J. Chapman et al.   EUROPEAN HEART JOURNAL

EUROASPIRE III: a survey on the lifestyle, risk factors and use of cardioprotective drug therapies in coronary patients from 22 European countries

(2009) Kornelia Kotseva et al.   EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION

Combined therapy in the treatment of dyslipidemia

(2009) Željko Reiner   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Major Lipids, Apolipoproteins, and Risk of Vascular Disease

(2009) The Emerging Risk Factors Collaboration*   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population

(2009) Uğur Hodoğlugil et al.   JOURNAL OF LIPID RESEARCH

Reconstituted High-Density Lipoprotein Increases Plasma High-Density Lipoprotein Anti-Inflammatory Properties and Cholesterol Efflux Capacity in Patients With Type 2 Diabetes

(2009) Sanjay Patel et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effects of High-Dose Modified-Release Nicotinic Acid on Atherosclerosis and Vascular Function

(2009) Justin M.S. Lee et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Plasma lipoproteins: genetic influences and clinical implications

(2009) Robert A. Hegele   NATURE REVIEWS GENETICS

Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes

(2009) Lars Wallentin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Extended-Release Niacin or Ezetimibe and Carotid Intima–Media Thickness

(2009) Allen J. Taylor et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ten-Year Mortality and Cardiovascular Morbidity in the Finnish Diabetes Prevention Study—Secondary Analysis of the Randomized Trial

(2009) Matti Uusitupa et al.   PLoS One

Basal very low-density lipoprotein metabolism in response to exercise: Mechanisms of hypotriacylglycerolemia

(2009) Faidon Magkos   PROGRESS IN LIPID RESEARCH

Relative and Cumulative Effects of Lipid and Blood Pressure Control in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels Trial

(2009) Pierre Amarenco et al.   STROKE

Comparison of the Safety and Efficacy of a Combination Tablet of Niacin Extended Release and Simvastatin vs Simvastatin Monotherapy in Patients With Increased Non–HDL Cholesterol (from the SEACOAST I Study)

(2008) Christie M. Ballantyne et al.   AMERICAN JOURNAL OF CARDIOLOGY

Mechanism of Action of Niacin

(2008) Vaijinath S. Kamanna et al.   AMERICAN JOURNAL OF CARDIOLOGY

Responses of Blood Lipids to Aerobic, Resistance, and Combined Aerobic With Resistance Exercise Training: A Systematic Review of Current Evidence

(2008) Konstantinos Tambalis et al.   ANGIOLOGY

Leukocyte Activation by Triglyceride-Rich Lipoproteins

(2008) Arash Alipour et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Extended-Release Niacin Alters the Metabolism of Plasma Apolipoprotein (Apo) A-I and ApoB-Containing Lipoproteins

(2008) Stefania Lamon-Fava et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Of Mice and Men

(2008) G.F. Watts et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

High-Density Lipoprotein Reduces the Human Monocyte Inflammatory Response

(2008) Andrew J. Murphy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Atorvastatin and Fenofibrate Have Comparable Effects on VLDL-Apolipoprotein C-III Kinetics in Men With the Metabolic Syndrome

(2008) Dick C. Chan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Torcetrapib Differentially Modulates the Biological Activities of HDL2 and HDL3 Particles in the Reverse Cholesterol Transport Pathway

(2008) Giovanna Catalano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants

(2008) Bernadette A.C. van Acker et al.   ATHEROSCLEROSIS

Smoking and smoking cessation—The relationship between cardiovascular disease and lipoprotein metabolism: A review

(2008) Sara Chelland Campbell et al.   ATHEROSCLEROSIS

Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone

(2008) M J Forrest et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lipids, Apolipoproteins, and Their Ratios in Relation to Cardiovascular Events With Statin Treatment

(2008) John J.P. Kastelein et al.   CIRCULATION

Infusion of Reconstituted High-Density Lipoprotein Leads to Acute Changes in Human Atherosclerotic Plaque

(2008) James A. Shaw et al.   CIRCULATION RESEARCH

Lipoprotein Management in Patients With Cardiometabolic Risk: Consensus statement from the American Diabetes Association and the American College of Cardiology Foundation

(2008) J. D. Brunzell et al.   DIABETES CARE

Effect of Lifestyle Intervention on the Occurrence of Metabolic Syndrome and its Components in the Finnish Diabetes Prevention Study

(2008) P. Ilanne-Parikka et al.   DIABETES CARE

Effects of Fenofibrate Treatment on Cardiovascular Disease Risk in 9,795 Individuals With Type 2 Diabetes and Various Components of the Metabolic Syndrome: The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study

(2008) R. Scott et al.   DIABETES CARE

Atorvastatin in Factorial with Omega-3 EE90 Risk Reduction in Diabetes (AFORRD): a randomised controlled trial

(2008) R. R. Holman et al.   DIABETOLOGIA

Nonfasting Triglycerides and Risk of Ischemic Stroke in the General Population

(2008) Jacob J. Freiberg   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association of Loss-of-Function Mutations in the ABCA1 Gene With High-Density Lipoprotein Cholesterol Levels and Risk of Ischemic Heart Disease

(2008) Ruth Frikke-Schmidt   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association of Cholesteryl Ester Transfer Protein Genotypes With CETP Mass and Activity, Lipid Levels, and Coronary Risk

(2008) Alexander Thompson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Acute exercise-induced changes in basal VLDL-triglyceride kinetics leading to hypotriglyceridemia manifest more readily after resistance than endurance exercise

(2008) Faidon Magkos et al.   JOURNAL OF APPLIED PHYSIOLOGY

Hepatic Lipase, Genetically Elevated High-Density Lipoprotein, and Risk of Ischemic Cardiovascular Disease

(2008) Trine Holm Johannsen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The metabolism and anti-atherogenic properties of HDL

(2008) Kerry-Anne Rye et al.   JOURNAL OF LIPID RESEARCH

Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation

(2008) Limin Wang et al.   JOURNAL OF LIPID RESEARCH

Long-Term Effects of Fenofibrate on Carotid Intima-Media Thickness and Augmentation Index in Subjects With Type 2 Diabetes Mellitus

(2008) Anne Hiukka et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Impact of Triglyceride Levels Beyond Low-Density Lipoprotein Cholesterol After Acute Coronary Syndrome in the PROVE IT-TIMI 22 Trial

(2008) Michael Miller et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

(2008) Cristen J Willer et al.   NATURE GENETICS

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Impact of progressive resistance training on lipids and lipoproteins in adults: A meta-analysis of randomized controlled trials

(2008) George A. Kelley et al.   PREVENTIVE MEDICINE

Nicotinic Acid: Pharmacological Effects and Mechanisms of Action

(2007) Andreas Gille et al.   Annual Review of Pharmacology and Toxicology