SUMOylation mediates the disassembly of the Smad4 nuclear export complex via RanGAP1 in KELOIDS

Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

(2020) Ana Tufegdžić Vidaković et al.   CELL

Sumoylation enhances the activity of the TGF-β/SMAD and HIF-1 signaling pathways in keloids

(2020) Xiaohu Lin et al.   LIFE SCIENCES

Manipulating PML SUMOylation via Silencing UBC9 and RNF4 Regulates Cardiac Fibrosis

(2017) Yu Liu et al.   MOLECULAR THERAPY

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor

(2017) Xingyue He et al.   Nature Chemical Biology

TGF-β Family Signaling in Tumor Suppression and Cancer Progression

(2017) Joan Seoane et al.   Cold Spring Harbor Perspectives in Biology

SUMOylation pathway alteration coupled with downregulation of SUMO E2 enzyme at mucosal epithelium modulates inflammation in inflammatory bowel disease

(2017) Salman Ahmad Mustfa et al.   Open Biology

A comprehensive compilation of SUMO proteomics

(2016) Ivo A. Hendriks et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes

(2016) Tobias Ritterhoff et al.   Nature Communications

SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies

(2016) Ya-Chen Liang et al.   Scientific Reports

Nuclear transport factors: global regulation of mitosis

(2015) Douglass J Forbes et al.   CURRENT OPINION IN CELL BIOLOGY

Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 Ligase Complex

(2015) Volkan Sakin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In situ structural analysis of the human nuclear pore complex

(2015) Alexander von Appen et al.   NATURE

Methionine adenosyltransferase α2 sumoylation positively regulate Bcl-2 expression in human colon and liver cancer cells

(2015) Maria Lauda Tomasi et al.   Oncotarget

Spatiotemporal Regulation of Nuclear Transport Machinery and Microtubule Organization

(2015) Naoyuki Okada et al.   Cells

Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores

(2012) Emanuele Roscioli et al.   JOURNAL OF CELL BIOLOGY

The RanBP2/RanGAP1∗SUMO1/Ubc9 Complex Is a Multisubunit SUMO E3 Ligase

(2012) Andreas Werner et al.   MOLECULAR CELL

Function and regulation of SUMO proteases

(2012) Christopher M. Hickey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SUMO Boosts the DNA Damage Response Barrier against Cancer

(2010) Jiri Bartek et al.   CANCER CELL

Elastic fiber assembly is disrupted by excessive accumulation of chondroitin sulfate in the human dermal fibrotic disease, keloid

(2009) Mika Ikeda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Principles of ubiquitin and SUMO modifications in DNA repair

(2009) Steven Bergink et al.   NATURE

Activity profiling of human deSUMOylating enzymes (SENPs) with synthetic substrates suggests an unexpected specificity of two newly characterized members of the family

(2008) Marcin Drag et al.   BIOCHEMICAL JOURNAL

Ubc9 promotes the stability of Smad4 and the nuclear accumulation of Smad1 in osteoblast-like Saos-2 cells

(2008) Koichi Shimada et al.   BONE

Nucleocytoplasmic shuttling of Smad proteins

(2008) Caroline S Hill   CELL RESEARCH

Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function

(2008) V. Vethantham et al.   GENES & DEVELOPMENT

SUMOylation Regulates Nuclear Localization of Krüppel-like Factor 5

(2008) James X. Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3

(2008) E. Evdokimov et al.   JOURNAL OF CELL SCIENCE

Spatial and temporal coordination of mitosis by Ran GTPase

(2008) Paul R. Clarke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of a nuclear export signal sequence for bovine papillomavirus E1 protein

(2008) Germán Rosas-Acosta et al.   VIROLOGY