α7- and α9-Containing Nicotinic Acetylcholine Receptors in the Functioning of Immune System and in Pain
出版年份 2023 全文链接
标题
α7- and α9-Containing Nicotinic Acetylcholine Receptors in the Functioning of Immune System and in Pain
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 24, Issue 7, Pages 6524
出版商
MDPI AG
发表日期
2023-03-31
DOI
10.3390/ijms24076524
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Human-specific duplicate CHRFAM7A gene is associated with more severe osteoarthritis and amplifies pain behaviours
- (2023) Alice Courties et al. ANNALS OF THE RHEUMATIC DISEASES
- Selective Agonists and Antagonists of α9 Versus α7 Nicotinic Acetylcholine Receptors
- (2022) Roger L. Papke et al. ACS Chemical Neuroscience
- Expression and Function of Nicotinic Acetylcholine Receptors in Induced Regulatory T Cells
- (2022) Yuichiro Nakata et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Role of Cholinergic Anti-Inflammatory Pathway in Protecting Sepsis-Induced Acute Lung Injury through Regulation of the Conventional Dendritic Cells
- (2022) Ruiting Li et al. MEDIATORS OF INFLAMMATION
- Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor
- (2022) Vasyl Bondarenko et al. Nature Communications
- Marine Origin Ligands of Nicotinic Receptors: Low Molecular Compounds, Peptides and Proteins for Fundamental Research and Practical Applications
- (2022) Igor Kasheverov et al. Biomolecules
- α-Conotoxin RgIA and oligoarginine R8 in the mice model alleviate long-term oxaliplatin induced neuropathy
- (2022) I.A. Dyachenko et al. BIOCHIMIE
- The Human-Restricted Isoform of the α7 nAChR, CHRFAM7A: A Double-Edged Sword in Neurological and Inflammatory Disorders
- (2022) Simona Di Lascio et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inflammation Regulation via an Agonist and Antagonists of α7 Nicotinic Acetylcholine Receptors in RAW264.7 Macrophages
- (2022) Yao Tan et al. Marine Drugs
- Comparison of the Anti-inflammatory Properties of Two Nicotinic Acetylcholine Receptor Ligands, Phosphocholine and pCF3-diEPP
- (2022) Katrin Richter et al. Frontiers in Cellular Neuroscience
- The α7 Nicotinic Acetylcholine Receptor Agonist GTS-21 Improves Bacterial Clearance via Regulation of Monocyte Recruitment and Activity in Polymicrobial Septic Peritonitis
- (2022) Jian-nan Hu et al. Frontiers in Immunology
- Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis
- (2022) Alice Courties et al. Frontiers in Immunology
- Oligo-basic amino acids, potential nicotinic acetylcholine receptor inhibitors
- (2022) Baojian Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- Preparation of uniform-sized GeXIVA[1,2]-loaded PLGA microspheres as long-effective release system with high encapsulation efficiency
- (2022) Lu Li et al. DRUG DELIVERY
- From 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624) to Selective Small-Molecule Antagonists of Human α9α10 Nicotinic Receptor by Modifications at the Ammonium Ethyl Residue
- (2022) Francesco Bavo et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Functional Interaction Between Y674-R685 Region of the SARS-CoV-2 Spike Protein and the Human α7 Nicotinic Receptor
- (2022) Juan Facundo Chrestia et al. MOLECULAR NEUROBIOLOGY
- The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors
- (2022) Mieke Nys et al. Nature Communications
- Tobacco product use and the risks of SARS-CoV-2 infection and COVID-19: current understanding and recommendations for future research
- (2022) Neal L Benowitz et al. Lancet Respiratory Medicine
- Activation of Cholinergic Anti-Inflammatory Pathway Ameliorates Cerebral and Cardiac Dysfunction After Intracerebral Hemorrhage Through Autophagy
- (2022) Yue Su et al. Frontiers in Immunology
- Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody
- (2022) Heather M. Callaway et al. Science Advances
- Discovery and Structural and Functional Characterization of a Novel A-Superfamily Conotoxin Targeting α9α10 Nicotinic Acetylcholine Receptor
- (2022) Qiuyuan Huang et al. ACS Chemical Biology
- Immunization with 674–685 fragment of SARS-Cov-2 spike protein induces neuroinflammation and impairs episodic memory of mice
- (2022) Olena Lykhmus et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The emergence of the uniquely human α7 nicotinic acetylcholine receptor gene and its roles in inflammation
- (2022) Wanling Peng et al. GENE
- An experimental test of the nicotinic hypothesis of COVID-19
- (2022) Nicole E. Godellas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting α7 nicotinic acetylcholine receptors for chronic pain
- (2022) Ya-Qun Zhou et al. Frontiers in Molecular Neuroscience
- Novel αO-conotoxin GeXIVA[1,2] Nonaddictive Analgesic with Pharmacokinetic Modelling-Based Mechanistic Assessment
- (2022) Xiaoyu Zhu et al. Pharmaceutics
- Up‐regulation of the human‐specific CHRFAM7A gene protects against renal fibrosis in mice with obstructive nephropathy
- (2022) Bingru Zhou et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Conus regius-Derived Conotoxins: Novel Therapeutic Opportunities from a Marine Organism
- (2022) Francesco Margiotta et al. Marine Drugs
- RgIA4 Prevention of Acute Oxaliplatin-Induced Cold Allodynia Requires α9-Containing Nicotinic Acetylcholine Receptors and CD3+ T-Cells
- (2022) Peter N. Huynh et al. Cells
- Membrane-mediated interaction of non-conventional snake three-finger toxins with nicotinic acetylcholine receptors
- (2022) Zakhar O. Shenkarev et al. Communications Biology
- Nicotinic Cholinergic System and COVID-19: In Silico Identification of Interactions Βetween α7 Nicotinic Acetylcholine Receptor and the Cryptic Epitopes of SARS-Co-V and SARS-CoV-2 Spike Glycoproteins
- (2021) George Lagoumintzis et al. FOOD AND CHEMICAL TOXICOLOGY
- A potential interaction between the SARS-CoV-2 spike protein and nicotinic acetylcholine receptors
- (2021) A. Sofia F. Oliveira et al. BIOPHYSICAL JOURNAL
- Lyophilization Serves as an Effective Strategy for Drug Development of the α9α10 Nicotinic Acetylcholine Receptor Antagonist α-Conotoxin GeXIVA[1,2]
- (2021) Zhiguo Li et al. Marine Drugs
- Street RABV Induces the Cholinergic Anti-inflammatory Pathway in Human Monocyte-Derived Macrophages by Binding to nAChr α7
- (2021) Carmen W. E. Embregts et al. Frontiers in Immunology
- Regulatory Dendritic Cells, T Cell Tolerance, and Dendritic Cell Therapy for Immunologic Disease
- (2021) Sara Ness et al. Frontiers in Immunology
- Disruption of the cholinergic anti-inflammatory response by R5-tropic HIV-1 protein gp120JRFL
- (2021) Sonnieliz Cotto Ríos et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors
- (2021) Shuai Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- New Pathways for the Skin's Stress Response: The Cholinergic Neuropeptide SLURP-1 Can Activate Mast Cells and Alter Cytokine Production in Mice
- (2021) Christoph M. Ertle et al. Frontiers in Immunology
- Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors
- (2021) Han-Shen Tae et al. BIOCHEMICAL PHARMACOLOGY
- Activation of α7 nicotinic acetylcholine receptor ameliorates HIV-associated neurology and neuropathology
- (2021) Xiaojie Zhao et al. BRAIN
- Selective Penicillamine Substitution Enables Development of a Potent Analgesic Peptide that Acts through a Non-Opioid-Based Mechanism
- (2021) Joanna Gajewiak et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of Methylene Thioacetal-Incorporated α-RgIA Analogues as Potent and Stable Antagonists of the Human α9α10 Nicotinic Acetylcholine Receptor for the Treatment of Neuropathic Pain
- (2021) Nan Zheng et al. JOURNAL OF MEDICINAL CHEMISTRY
- Therapeutic Targeting of α7 Nicotinic Acetylcholine Receptors
- (2021) Roger L. Papke et al. PHARMACOLOGICAL REVIEWS
- ɑO‐Conotoxin GeXIVA isomers modulate N‐type calcium (Ca V 2.2) channels and inwardly‐rectifying potassium (GIRK) channels via GABA B receptor activation
- (2021) Arsalan Yousuf et al. JOURNAL OF NEUROCHEMISTRY
- Smoking and COVID-19 outcomes: an observational and Mendelian randomisation study using the UK Biobank cohort
- (2021) Ashley K Clift et al. THORAX
- COVID-19 and Smoking. Is Nicotine the Hidden Link?
- (2020) Patrizia Russo et al. EUROPEAN RESPIRATORY JOURNAL
- Systematic review of the prevalence of current smoking among hospitalized COVID-19 patients in China: could nicotine be a therapeutic option?
- (2020) Konstantinos Farsalinos et al. Internal and Emergency Medicine
- Human secreted protein SLURP-1 abolishes nicotine-induced proliferation, PTEN down-regulation and α7-nAChR expression up-regulation in lung cancer cells
- (2020) Mikhail A. Shulepko et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- α7 nAChRs expressed on antigen presenting cells are insensitive to the conventional antagonists α-bungarotoxin and methyllycaconitine
- (2020) Masato Mashimo et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Water‐soluble variant of human Lynx1 positively modulates synaptic plasticity and ameliorates cognitive impairment associated with α7‐nAChR dysfunction
- (2020) Zakhar O. Shenkarev et al. JOURNAL OF NEUROCHEMISTRY
- Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins
- (2020) Md. Mahfuzur Rahman et al. NEURON
- Chemotherapy-induced peripheral neuropathy—part 2: focus on the prevention of oxaliplatin-induced neurotoxicity
- (2020) Kinga Sałat Pharmacological Reports
- Implications for Neuromodulation Therapy to Control Inflammation and Related Organ Dysfunction in COVID-19
- (2020) Marat Fudim et al. Journal of Cardiovascular Translational Research
- Activation of α7 Nicotinic Acetylcholine Receptor Upregulates HLA-DR and Macrophage Receptors: Potential Role in Adaptive Immunity and in Preventing Immunosuppression
- (2020) Andrei E. Siniavin et al. Biomolecules
- How nicotine can inhibit cytokine storm in the lungs and prevent or lessen the severity of COVID-19 infection?
- (2020) Malgorzata Kloc et al. IMMUNOLOGY LETTERS
- Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications
- (2020) Konstantinos Farsalinos et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Three‐finger proteins from snakes and humans acting on nicotinic receptors: Old and new
- (2020) Victor I. Tsetlin et al. JOURNAL OF NEUROCHEMISTRY
- Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors
- (2020) Alexander S. Paramonov et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists
- (2020) M. Allahverdi Khani et al. MEDICAL HYPOTHESES
- α9α10 nicotinic acetylcholine receptors regulate murine bone marrow granulocyte functions
- (2020) Valentina G. Safronova et al. IMMUNOBIOLOGY
- Structure-Function of Neuronal Nicotinic Acetylcholine Receptor Inhibitors Derived From Natural Toxins
- (2020) Thao N. T. Ho et al. Frontiers in Neuroscience
- Role of the α7 Nicotinic Acetylcholine Receptor in the Pathophysiology of Atherosclerosis
- (2020) Ildernandes Vieira-Alves et al. Frontiers in Physiology
- Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models
- (2020) Konstantin S. Mineev et al. Biomolecules
- Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor
- (2020) Xiao Li et al. PHARMACOLOGY & THERAPEUTICS
- Conopeptides [V11L;V16D]ArIB and RgIA4: Powerful Tools for the Identification of Novel Nicotinic Acetylcholine Receptors in Monocytes
- (2019) Veronika Grau et al. Frontiers in Pharmacology
- Association of a functional polymorphism in the CHRFAM7A gene with inflammatory response mediators and neuropathic pain after spinal cord injury
- (2019) Wan Huang et al. JOURNAL OF NEUROTRAUMA
- The α9α10 Nicotinic Acetylcholine Receptor Antagonist αO-Conotoxin GeXIVA[1,2] Alleviates and Reverses Chemotherapy-Induced Neuropathic Pain
- (2019) Huanbai Wang et al. Marine Drugs
- The secreted Ly6/uPAR-related protein-1 suppresses neutrophil binding, chemotaxis, and transmigration through human umbilical vein endothelial cells
- (2019) Sudha Swamynathan et al. Scientific Reports
- Lynx Prototoxins: Roles of Endogenous Mammalian Neurotoxin-Like Proteins in Modulating Nicotinic Acetylcholine Receptor Function to Influence Complex Biological Processes
- (2019) Julie M. Miwa et al. Frontiers in Pharmacology
- Crystal Structure of the Monomeric Extracellular Domain of α9 Nicotinic Receptor Subunit in Complex With α-Conotoxin RgIA: Molecular Dynamics Insights Into RgIA Binding to α9α10 Nicotinic Receptors
- (2019) Marios Zouridakis et al. Frontiers in Pharmacology
- Acetylcholine-producing T-cells augment innate immune driven colitis but are redundant in T-cell driven colitis
- (2019) Rose A Willemze et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Effect of donepezil on the expression and responsiveness to LPS of CHRNA7 and CHRFAM7A in macrophages: A possible link to the cholinergic anti-inflammatory pathway
- (2019) Annalisa Maroli et al. JOURNAL OF NEUROIMMUNOLOGY
- From Synthetic Fragments of Endogenous Three-Finger Proteins to Potential Drugs
- (2019) Elena V. Kryukova et al. Frontiers in Pharmacology
- Emerging Role of Lymphocyte Antigen-6 Family of Genes in Cancer and Immune Cells
- (2019) Geeta Upadhyay Frontiers in Immunology
- Distinct Roles of α7 nAChRs in Antigen-Presenting Cells and CD4+ T Cells in the Regulation of T Cell Differentiation
- (2019) Masato Mashimo et al. Frontiers in Immunology
- α-Conotoxin Vc1.1 Structure–Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement
- (2019) Xin Chu et al. ACS Chemical Neuroscience
- Oligoarginine Peptides, a New Family of nAChR Inhibitors
- (2019) Dmitry Lebedev et al. MOLECULAR PHARMACOLOGY
- The secreted Ly-6/uPAR related protein-1 (SLURP1) stabilizes epithelial cell junctions and suppresses TNF-α-induced cytokine production
- (2019) Gregory Campbell et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Migration of gastric cancer is suppressed by recombinant Newcastle disease virus (rL-RVG) via regulating α7-nicotinic acetylcholine receptors/ERK- EMT
- (2019) Xuefeng Bu et al. BMC CANCER
- Conotoxins: Chemistry and Biology
- (2019) Ai-Hua Jin et al. CHEMICAL REVIEWS
- RgIA4 Accelerates Recovery from Paclitaxel-Induced Neuropathic Pain in Rats
- (2019) Peter N. Huynh et al. Marine Drugs
- Human secreted proteins SLURP-1 and SLURP-2 control the growth of epithelial cancer cells via interactions with nicotinic acetylcholine receptors
- (2018) E N Lyukmanova et al. BRITISH JOURNAL OF PHARMACOLOGY
- Beyond symptomatic relief for chemotherapy-induced peripheral neuropathy: Targeting the source
- (2018) Jiacheng Ma et al. CANCER
- Nicotinic Acetylcholine Receptors in HIV: Possible Roles During HAND and Inflammation
- (2018) Coral M. Capó-Vélez et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- The Cholinergic Anti-Inflammatory Response and the Role of Macrophages in HIV-Induced Inflammation
- (2018) Manuel Delgado-Vélez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- α7 nicotinic acetylcholine receptors are involved in suppression of the antibody immune response
- (2018) Lyudmyla Koval et al. JOURNAL OF NEUROIMMUNOLOGY
- Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails
- (2018) Nikita Abraham et al. Marine Drugs
- Species specificity of rat and human α7 nicotinic acetylcholine receptors towards different classes of peptide and protein antagonists
- (2018) Jinpeng Yu et al. NEUROPHARMACOLOGY
- OUP accepted manuscript
- (2018) PAIN MEDICINE
- Augmenting the antinociceptive effects of nicotinic acetylcholine receptor activity through lynx1 modulation
- (2018) Neel I. Nissen et al. PLoS One
- Beyond the Channel: Metabotropic Signaling by Nicotinic Receptors
- (2018) Nadine Kabbani et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Endogenous CHRNA7-ligand SLURP1 as a potential tumor suppressor and anti-nicotinic factor in pancreatic cancer
- (2018) Verena M. Throm et al. Oncotarget
- Synthesis, Structure and Biological Activity of CIA and CIB, Two α-Conotoxins from the Predation-Evoked Venom of Conus catus
- (2018) Julien Giribaldi et al. Toxins
- The antinociceptive and anti-inflammatory properties of the α7 nAChR weak partial agonistp-CF3N,N-diethyl-N’-phenylpiperazine
- (2018) Marta Quadri et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Phosphocholine-Modified Lipooligosaccharides of Haemophilus influenzae Inhibit ATP-Induced IL-1β Release by Pulmonary Epithelial Cells
- (2018) Katrin Richter et al. MOLECULES
- C-Reactive Protein Stimulates Nicotinic Acetylcholine Receptors to Control ATP-Mediated Monocytic Inflammasome Activation
- (2018) Katrin Richter et al. Frontiers in Immunology
- Adenylyl Cyclase 6 Mediates Inhibition of TNF in the Inflammatory Reflex
- (2018) Laura Tarnawski et al. Frontiers in Immunology
- Surfactant inhibits ATP-induced release of interleukin-1β via nicotinic acetylcholine receptors
- (2017) Sören Backhaus et al. JOURNAL OF LIPID RESEARCH
- Physiological functions of the cholinergic system in immune cells
- (2017) Takeshi Fujii et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine Receptor
- (2017) Shantong Jiang et al. Marine Drugs
- Cloning, expression and functional characterization of a D-superfamily conotoxin Lt28.1 with previously undescribed cysteine pattern
- (2017) Jianbo Lu et al. PEPTIDES
- Acetylcholine-producing NK cells attenuate CNS inflammation via modulation of infiltrating monocytes/macrophages
- (2017) Wei Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain
- (2017) Haylie K. Romero et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia
- (2017) Sean B. Christensen et al. Frontiers in Cellular Neuroscience
- Canonical and Novel Non-Canonical Cholinergic Agonists Inhibit ATP-Induced Release of Monocytic Interleukin-1β via Different Combinations of Nicotinic Acetylcholine Receptor Subunits α7, α9 and α10
- (2017) Anna Zakrzewicz et al. Frontiers in Cellular Neuroscience
- Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors
- (2017) Thomas Durek et al. Scientific Reports
- Expression and Function of the Cholinergic System in Immune Cells
- (2017) Takeshi Fujii et al. Frontiers in Immunology
- Rabies virus modifies host behaviour through a snake-toxin like region of its glycoprotein that inhibits neurotransmitter receptors in the CNS
- (2017) Karsten Hueffer et al. Scientific Reports
- Effects of α-conotoxin ImI on TNF-α, IL-8 and TGF-β expression by human macrophage-like cells derived from THP-1 pre-monocytic leukemic cells
- (2017) Alberto Padilla et al. Scientific Reports
- Acetylcholine polarizes dendritic cells toward a Th2-promoting profile
- (2016) S. Gori et al. ALLERGY
- Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif
- (2016) Bodil B. Carstens et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The α9α10 nicotinic receptor antagonist α-conotoxin RgIA prevents neuropathic pain induced by oxaliplatin treatment
- (2016) Alessandra Pacini et al. EXPERIMENTAL NEUROLOGY
- Nicotinic receptor involvement in regulation of functions of mouse neutrophils from inflammatory site
- (2016) Valentina G. Safronova et al. IMMUNOBIOLOGY
- Expression and Functional Role of α7 Nicotinic Receptor in Human Cytokine-stimulated Natural Killer (NK) Cells
- (2016) Samanta R. Zanetti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Infiltration of CCR2+Ly6ChighProinflammatory Monocytes and Neutrophils into the Central Nervous System Is Modulated by Nicotinic Acetylcholine Receptors in a Model of Multiple Sclerosis
- (2016) Wei Jiang et al. JOURNAL OF IMMUNOLOGY
- Nicotine induces neutrophil extracellular traps
- (2016) Ava Hosseinzadeh et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The Neuroprotective Peptide Poly-Arginine-12 (R12) Reduces Cell Surface Levels of NMDA NR2B Receptor Subunit in Cortical Neurons; Investigation into the Involvement of Endocytic Mechanisms
- (2016) Gabriella MacDougall et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs
- (2016) Bo Lin et al. Marine Drugs
- Nicotinic Acetylcholine Receptors Modulate Bone Marrow-Derived Pro-Inflammatory Monocyte Production and Survival
- (2016) Stéphanie St-Pierre et al. PLoS One
- Anti-hypersensitive effect of intramuscular administration of αO-conotoxin GeXIVA[1,2] and GeXIVA[1,4] in rats of neuropathic pain
- (2016) Xiaodan Li et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- High-Affinity α-Conotoxin PnIA Analogs Designed on the Basis of the Protein Surface Topography Method
- (2016) Igor E. Kasheverov et al. Scientific Reports
- Phosphocholine – an agonist of metabotropic but not of ionotropic functions of α9-containing nicotinic acetylcholine receptors
- (2016) K. Richter et al. Scientific Reports
- Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of α7 Nicotinic Acetylcholine Receptor
- (2016) Ekaterina N. Lyukmanova et al. PLoS One
- αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors
- (2015) Sean B. Christensen et al. BIOCHEMICAL PHARMACOLOGY
- Acetylcholine Inhibits LPS-Induced MMP-9 Production and Cell Migration via the a7 nAChR-JAK2/STAT3 Pathway in RAW264.7 Cells
- (2015) Yong-Hua Yang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Non-neuronal cholinergic system in regulation of immune function with a focus on α7 nAChRs
- (2015) Koichiro Kawashima et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1β Release
- (2015) Andreas Hecker et al. JOURNAL OF IMMUNOLOGY
- Structural and Functional Characterization of a Novel α-Conotoxin Mr1.7 from Conus marmoreus Targeting Neuronal nAChR α3β2, α9α10 and α6/α3β2β3 Subtypes
- (2015) Shuo Wang et al. Marine Drugs
- Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist
- (2015) Sulan Luo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nicotine Exposure Alters the mRNA Expression of Notch Ligands in Dendritic Cells and Their Response to Th1-/Th2-Promoting Stimuli
- (2015) M. Nouri-Shirazi et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Three-finger snake neurotoxins and Ly6 proteins targeting nicotinic acetylcholine receptors: pharmacological tools and endogenous modulators
- (2015) Victor I. Tsetlin TRENDS IN PHARMACOLOGICAL SCIENCES
- Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?
- (2015) Sarasa Mohammadi et al. Toxins
- Functional expression and axonal transport of α7 nAChRs by peptidergic nociceptors of rat dorsal root ganglion
- (2014) Irina Shelukhina et al. Brain Structure & Function
- Discovery, Synthesis, and Structure–Activity Relationships of Conotoxins
- (2014) Kalyana B. Akondi et al. CHEMICAL REVIEWS
- Structure-Function Elucidation of a New α-Conotoxin, Lo1a, fromConus longurionis
- (2014) Eline K. M. Lebbe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Duplicated α7 Subunits Assemble and Form Functional Nicotinic Receptors with the Full-length α7
- (2014) Ying Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conotoxins Targeting Nicotinic Acetylcholine Receptors: An Overview
- (2014) Eline Lebbe et al. Marine Drugs
- α9-Nicotinic Acetylcholine Receptors Contribute to the Maintenance of Chronic Mechanical Hyperalgesia, but Not Thermal or Mechanical Allodynia
- (2014) Sarasa Mohammadi et al. Molecular Pain
- α-Conotoxin RgIA protects against the development of nerve injury-induced chronic pain and prevents both neuronal and glial derangement
- (2014) Lorenzo Di Cesare Mannelli et al. PAIN
- Discovery of a new subclass of α-conotoxins in the venom of Conus australis
- (2014) Eline K.M. Lebbe et al. TOXICON
- Isolation, purification and functional characterization of alpha-BnIA from Conus bandanus venom
- (2014) Bao Nguyen et al. TOXICON
- Anti-Inflammatory Effects of the Nicotinergic Peptides SLURP-1 and SLURP-2 on Human Intestinal Epithelial Cells and Immunocytes
- (2014) Alex I. Chernyavsky et al. Biomed Research International
- Dicarba α-Conotoxin Vc1.1 Analogues with Differential Selectivity for Nicotinic Acetylcholine and GABAB Receptors
- (2013) Bianca J. van Lierop et al. ACS Chemical Biology
- Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors
- (2013) Marco C. Inserra et al. BIOCHEMICAL PHARMACOLOGY
- MrIC, a Novel α-Conotoxin Agonist in the Presence of PNU at Endogenous α7 Nicotinic Acetylcholine Receptors
- (2013) Ai-Hua Jin et al. BIOCHEMISTRY
- Determination of the α-Conotoxin Vc1.1 Binding Site on the α9α10 Nicotinic Acetylcholine Receptor
- (2013) Rilei Yu et al. JOURNAL OF MEDICINAL CHEMISTRY
- SLURP-1, an endogenous α7 nicotinic acetylcholine receptor allosteric ligand, is expressed in CD205+ dendritic cells in human tonsils and potentiates lymphocytic cholinergic activity
- (2013) Takeshi Fujii et al. JOURNAL OF NEUROIMMUNOLOGY
- Nicotinic Receptor β2 Determines NK Cell-Dependent Metastasis in a Murine Model of Metastatic Lung Cancer
- (2013) Junwei Hao et al. PLoS One
- Lymphocyte-derived ACh regulates local innate but not adaptive immunity
- (2013) Colin Reardon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor Necrosis Factor-α Signaling in Macrophages
- (2012) Narayanan Parameswaran et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- γ-Aminobutyric Acid Type B (GABAB) Receptor Expression Is Needed for Inhibition of N-type (Cav2.2) Calcium Channels by Analgesic α-Conotoxins
- (2012) Hartmut Cuny et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Layla Azam et al. JOURNAL OF NEUROCHEMISTRY
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- (2012) Esmerij P. van der Zanden et al. NEUROIMMUNOMODULATION
- Intrathecal α-conotoxins Vc1.1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic pain
- (2012) I.A. Napier et al. NEUROPHARMACOLOGY
- The chimeric gene CHRFAM7A, a partial duplication of the CHRNA7 gene, is a dominant negative regulator of α7*nAChR function
- (2011) Tanguy Araud et al. BIOCHEMICAL PHARMACOLOGY
- RegIIA: An α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs
- (2011) Aldo Franco et al. BIOCHEMICAL PHARMACOLOGY
- Analgesic conotoxins: block and G protein-coupled receptor modulation of N-type (CaV2.2) calcium channels
- (2011) David J Adams et al. BRITISH JOURNAL OF PHARMACOLOGY
- The novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic
- (2011) Joseph R. Holtman et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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- (2011) Julia Radosa et al. EXPERIMENTAL DERMATOLOGY
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- (2011) Ekaterina N. Lyukmanova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Helena Safavi-Hemami et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure and Activity of α-Conotoxin PeIA at Nicotinic Acetylcholine Receptor Subtypes and GABABReceptor-coupled N-type Calcium Channels
- (2011) Norelle L. Daly et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α7-Cholinergic Receptor Mediates Vagal Induction of Splenic Norepinephrine
- (2011) Gergely Vida et al. JOURNAL OF IMMUNOLOGY
- Assembly of nicotinic and other Cys-loop receptors
- (2011) Victor Tsetlin et al. JOURNAL OF NEUROCHEMISTRY
- Design of New α-Conotoxins: From Computer Modeling to Synthesis of Potent Cholinergic Compounds
- (2011) Igor E. Kasheverov et al. Marine Drugs
- Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit
- (2011) M. Rosas-Ballina et al. SCIENCE
- Analgesic α-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in sensory neurons of α9 nicotinic receptor knockout mice
- (2010) Brid Callaghan et al. Channels
- Function of Partially Duplicated Human α7 Nicotinic Receptor SubunitCHRFAM7AGene
- (2010) Ana M. de Lucas-Cerrillo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nicotine Inhibits Fc RI-Induced Cysteinyl Leukotrienes and Cytokine Production without Affecting Mast Cell Degranulation Through 7/ 9/ 10-Nicotinic Receptors
- (2010) N. C. Mishra et al. JOURNAL OF IMMUNOLOGY
- Stimulation of 7 Nicotinic Acetylcholine Receptor by Nicotine Increases Suppressive Capacity of Naturally Occurring CD4+CD25+ Regulatory T Cells in Mice In Vitro
- (2010) D.-w. Wang et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Structural and phylogenetic characterization of human SLURP-1, the first secreted mammalian member of the Ly-6/uPAR protein superfamily
- (2010) Knut Adermann et al. PROTEIN SCIENCE
- Alpha9 nicotinic acetylcholine receptors and the treatment of pain
- (2009) J. Michael McIntosh et al. BIOCHEMICAL PHARMACOLOGY
- Auto/paracrine control of inflammatory cytokines by acetylcholine in macrophage-like U937 cells through nicotinic receptors
- (2009) Alexander I. Chernyavsky et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- A Synthetic Combinatorial Strategy for Developing α-Conotoxin Analogs as Potent α7Nicotinic Acetylcholine Receptor Antagonists
- (2009) Christopher J. Armishaw et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of the Cholinergic Anti-Inflammatory System by Nicotine Attenuates Neuroinflammation via Suppression of Th1 and Th17 Responses
- (2009) E. Nizri et al. JOURNAL OF IMMUNOLOGY
- Requisite Role of the Cholinergic α7 Nicotinic Acetylcholine Receptor Pathway in Suppressing Gram-Negative Sepsis-Induced Acute Lung Inflammatory Injury
- (2009) Xiao Su et al. JOURNAL OF IMMUNOLOGY
- Nicotine-mediated signals modulate cell death and survival of T lymphocytes
- (2009) Silvia C.S. Oloris et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- IgE-induced degranulation of mucosal mast cells is negatively regulated via nicotinic acetylcholine receptors
- (2008) Natsuko Kageyama-Yahara et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Analgesic -Conotoxins Vc1.1 and Rg1A Inhibit N-Type Calcium Channels in Rat Sensory Neurons via GABAB Receptor Activation
- (2008) B. Callaghan et al. JOURNAL OF NEUROSCIENCE
- Synthesis and Characterization of 125I- -Conotoxin ArIB[V11L;V16A], a Selective 7 Nicotinic Acetylcholine Receptor Antagonist
- (2008) P. Whiteaker et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Conotoxin Arenatus IB[V11L,V16D] Is a Potent and Selective Antagonist at Rat and Human Native 7 Nicotinic Acetylcholine Receptors
- (2008) N. Innocent et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Functions of natural killer cells
- (2008) Eric Vivier et al. NATURE IMMUNOLOGY
- Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia
- (2008) M. Rosas-Ballina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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