Cross-talk between energy and redox metabolism in astrocyte-neuron functional cooperation

Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis

(2022) Irene Lopez-Fabuel et al.   Nature Communications

Amyloid-β Induces Cdh1-Mediated Rock2 Stabilization Causing Neurodegeneration

(2022) Rebeca Lapresa et al.   Frontiers in Pharmacology

Differential role of neuronal glucose and PFKFB3 in memory formation during development

(2022) Emmanuel Cruz et al.   GLIA

Lactate transporters in the rat barrel cortex sustain whisker-dependent BOLD fMRI signal and behavioral performance

(2021) Hélène Roumes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal Activity and Its Role in Controlling Antioxidant Genes

(2020) Jing Qiu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glucose metabolism links astroglial mitochondria to cannabinoid effects

(2020) Daniel Jimenez-Blasco et al.   NATURE

Neuronal and astroglial monocarboxylate transporters play key but distinct roles in hippocampus-dependent learning and memory formation

(2020) Citlalli Netzahualcoyotzi et al.   PROGRESS IN NEUROBIOLOGY

Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice

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Lactate in the brain: from metabolic end-product to signalling molecule

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Glia-neuron energy metabolism in health and diseases: New insights into the role of nervous system metabolic transporters

(2018) Mithilesh Kumar Jha et al.   EXPERIMENTAL NEUROLOGY

Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function

(2018) Seila Fernandez-Fernandez et al.   Redox Biology

APC-Cdh1 Regulates Neuronal Apoptosis Through Modulating Glycolysis and Pentose-Phosphate Pathway After Oxygen-Glucose Deprivation and Reperfusion

(2018) Zuofan Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Transcriptional Regulation by Nrf2

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Supramolecular Organization of Respiratory Complexes

(2016) José Antonio Enríquez   Annual Review of Physiology

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons

(2016) Philipp Mächler et al.   Cell Metabolism

Altered Energy Metabolism Pathways in the Posterior Cingulate in Young Adult Apolipoprotein E ɛ4 Carriers

(2016) Michelle Perkins et al.   JOURNAL OF ALZHEIMERS DISEASE

Bioenergetics and redox adaptations of astrocytes to neuronal activity

(2016) Juan P. Bolaños   JOURNAL OF NEUROCHEMISTRY

Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes

(2016) Irene Lopez-Fabuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Interplay Between Respiratory Supercomplexes and ROS in Aging

(2015) Maria Luisa Genova et al.   ANTIOXIDANTS & REDOX SIGNALING

Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5–Nrf2 pathway

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Glial Glycolysis Is Essential for Neuronal Survival in Drosophila

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Bioenergetic Mechanisms in Astrocytes May Contribute to Amyloid Plaque Deposition and Toxicity

(2015) Wen Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Bcl-xL-ATP Synthase Interaction by Mitochondrial Cyclin B1-Cyclin-Dependent Kinase-1 Determines Neuronal Survival

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Changes in lactate content and monocarboxylate transporter 2 expression in Aβ25-35-treated rat model of Alzheimer’s disease

(2015) Weitian Lu et al.   NEUROLOGICAL SCIENCES

A Cellular Perspective on Brain Energy Metabolism and Functional Imaging

(2015) Pierre J. Magistretti et al.   NEURON

Do stars govern our actions? Astrocyte involvement in rodent behavior

(2015) João Filipe Oliveira et al.   TRENDS IN NEUROSCIENCES

Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

(2015) Karen F.S. Bell et al.   Nature Communications

Uncertainties in pentose-phosphate pathway flux assessment underestimate its contribution to neuronal glucose consumption: relevance for neurodegeneration and aging

(2015) Anne-Karine Bouzier-Sore et al.   Frontiers in Aging Neuroscience

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Nrf2 target genes can be controlled by neuronal activity in the absence of Nrf2 and astrocytes

(2014) R. F. Deighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Neuron-glia networks: integral gear of brain function

(2014) Gertrudis Perea et al.   Frontiers in Cellular Neuroscience

PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1

(2014) Raquel Requejo-Aguilar et al.   Nature Communications

Structures of mitochondrial oxidative phosphorylation supercomplexes and mechanisms for their stabilisation

(2013) Yuriy Chaban et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The Hallmarks of Aging

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Brain energy metabolism in glutamate-receptor activation and excitotoxicity: Role for APC/C-Cdh1 in the balance glycolysis/pentose phosphate pathway

(2013) Patricia Rodriguez-Rodriguez et al.   NEUROCHEMISTRY INTERNATIONAL

Neuronal activity regulates astrocytic Nrf2 signaling

(2013) A. Habas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APC/C-Cdh1 coordinates neurogenesis and cortical size during development

(2013) Maria Delgado-Esteban et al.   Nature Communications

Antioxidant and bioenergetic coupling between neurons and astrocytes

(2012) Seila Fernandez-Fernandez et al.   BIOCHEMICAL JOURNAL

Endothelial Cell-Derived Nitric Oxide Enhances Aerobic Glycolysis in Astrocytes via HIF-1 -Mediated Target Gene Activation

(2012) B. Brix et al.   JOURNAL OF NEUROSCIENCE

Regulation of APC/C-Cdh1 and Its Function in Neuronal Survival

(2012) Angeles Almeida   MOLECULAR NEUROBIOLOGY

γ-Glutamylcysteine detoxifies reactive oxygen species by acting as glutathione peroxidase-1 cofactor

(2012) Ruben Quintana-Cabrera et al.   Nature Communications

Sweet Sixteen for ANLS

(2011) Luc Pellerin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Fast and Reversible Stimulation of Astrocytic Glycolysis by K+ and a Delayed and Persistent Effect of Glutamate

(2011) C. X. Bittner et al.   JOURNAL OF NEUROSCIENCE

Activation of Nrf2-Regulated Glutathione Pathway Genes by Ischemic Preconditioning

(2011) Karen F. S. Bell et al.   Oxidative Medicine and Cellular Longevity

Cancer Chemoprevention Mechanisms Mediated Through the Keap1–Nrf2 Pathway

(2010) John D. Hayes et al.   ANTIOXIDANTS & REDOX SIGNALING

Control of Redox State and Redox Signaling by Neural Antioxidant Systems

(2010) Jan Lewerenz et al.   ANTIOXIDANTS & REDOX SIGNALING

The sites and topology of mitochondrial superoxide production

(2010) Martin D. Brand   EXPERIMENTAL GERONTOLOGY

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

(2010) K. F. Bell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for proteasome inhibitor-mediated cardioprotection

(2009) H. Dreger et al.   CARDIOVASCULAR RESEARCH

Regulation of Cdh1-APC Function in Axon Growth by Cdh1 Phosphorylation

(2009) M. A. Huynh et al.   JOURNAL OF NEUROSCIENCE

Neuroscience: Glia — more than just brain glue

(2009) Nicola J. Allen et al.   NATURE

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

(2009) Angel Herrero-Mendez et al.   NATURE CELL BIOLOGY

Molecular Motors and Synaptic Assembly

(2009) Qian Cai et al.   NEUROSCIENTIST

Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents

(2009) Larry G. Higgins et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Glycolysis: a bioenergetic or a survival pathway?

(2009) Juan P. Bolaños et al.   TRENDS IN BIOCHEMICAL SCIENCES

Regulation of APC/C Activators in Mitosis and Meiosis

(2008) Jillian A. Pesin et al.   Annual Review of Cell and Developmental Biology

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity

(2008) Carolina Maestre et al.   EMBO JOURNAL

Antioxidants and Phase 2 Enzymes in Macrophages: Regulation by Nrf2 Signaling and Protection Against Oxidative and Electrophilic Stress

(2008) Hong Zhu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The Anaphase Promoting Complex Induces Substrate Degradation during Neuronal Differentiation

(2008) Dympna Harmey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical and molecular characterisation of a Parkinson family with a novel PINK1 mutation

(2008) J. Prestel et al.   JOURNAL OF NEUROLOGY

Genomic stability and tumour suppression by the APC/C cofactor Cdh1

(2008) Irene García-Higuera et al.   NATURE CELL BIOLOGY

Astrocytic involvement in learning and memory consolidation

(2008) Marie E. Gibbs et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

(2008) Claire Henchcliffe et al.   Nature clinical practice. Neurology

Na+-Ca2+cosignaling in the stimulation of the glucose transporter GLUT1 in cultured astrocytes

(2007) Omar H. Porras et al.   GLIA