Concise review on the combined use of immunocapture, mass spectrometry and liquid chromatography for clinical applications

Coupling immuno-magnetic capture with LC–MS/MS(MRM) as a sensitive, reliable, and specific assay for SARS-CoV-2 identification from clinical samples

(2022) Ofir Schuster et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Intact quantitative bioanalytical method development and fit-for-purpose validation of a monoclonal antibody and its related fab fragment in human vitreous and aqueous humor using LC-HRMS

(2022) Catherine E. DelGuidice et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

High-Resolution Mass Spectrometry for the Measurement of PTH and PTH Fragments: Insights into PTH Physiology and Bioactivity

(2022) Candice Z. Ulmer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Immunopeptidomics: Reading the Immune Signal That Defines Self From Nonself

(2022) Pierre Thibault et al.   MOLECULAR & CELLULAR PROTEOMICS

Selective quantification of the 22-kDa isoform of human growth hormone 1 in serum and plasma by immunocapture and LC–MS/MS

(2022) Bas Sleumer et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Using MetaboAnalyst 5.0 for LC–HRMS spectra processing, multi-omics integration and covariate adjustment of global metabolomics data

(2022) Zhiqiang Pang et al.   Nature Protocols

A streamlined platform for analyzing tera-scale DDA and DIA mass spectrometry data enables highly sensitive immunopeptidomics

(2022) Lei Xin et al.   Nature Communications

Isotyping and Semi-Quantitation of Monkey Anti-Drug Antibodies by Immunocapture Liquid Chromatography-Mass Spectrometry

(2021) Xiaoxiao Huang et al.   AAPS Journal

Chemical Characterization and Quantification of Circulating Intact PTH and PTH Fragments by High-Resolution Mass Spectrometry in Chronic Renal Failure

(2021) Kittrawee Kritmetapak et al.   CLINICAL CHEMISTRY

Development, Validation, and Comparison of Two Mass Spectrometry Methods (LC-MS/HRMS and LC-MS/MS) for the Quantification of Rituximab in Human Plasma

(2021) Aurélien Millet et al.   MOLECULES

Analytical and Clinical Performance of a Liquid Chromatography–Tandem Mass Spectrometry Method for Measuring Gastrin Subtypes G34 and G17 in Serum

(2021) Songlin Yu et al.   CLINICAL CHEMISTRY

Validated Method Based on Immunocapture and Liquid Chromatography Coupled to High-Resolution Mass Spectrometry to Eliminate Isatuximab Interference with M-Protein Measurement in Serum

(2021) Stéphane Muccio et al.   ANALYTICAL CHEMISTRY

Identification of tumor antigens with immunopeptidomics

(2021) Chloe Chong et al.   NATURE BIOTECHNOLOGY

The pathway through LC-MS method development: in-house or ready-to-use kit-based methods?

(2020) Caroline Le Goff et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Intact protein quantification in biological samples by liquid chromatography – high-resolution mass spectrometry: somatropin in rat plasma

(2020) Peter Bults et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Fit-for-purpose protein biomarker assay validation strategies using hybrid immunocapture-liquid chromatography-tandem-mass spectrometry platform: Quantitative analysis of total soluble cluster of differentiation 73

(2020) Yue Zhao et al.   ANALYTICA CHIMICA ACTA

Biosensors and Bioanalytical Devices based on Magnetic Particles, a Review

(2020) Miroslav Pohanka   CURRENT MEDICINAL CHEMISTRY

Antipeptide Immunocapture with In-Sample Calibration Curve Strategy for Sensitive and Robust LC-MS/MS Bioanalysis of Clinical Protein Biomarkers in Formalin-Fixed Paraffin-Embedded Tumor Tissues

(2020) Naiyu Zheng et al.   ANALYTICAL CHEMISTRY

Intact Protein Mass Spectrometry for Therapeutic Protein Quantitation, Pharmacokinetics, and Biotransformation in Preclinical and Clinical Studies: An Industry Perspective

(2020) John F. Kellie et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Evaluating Isatuximab Interference with Monoclonal Protein Detection By Immuno-Capture and Liquid Chromatography Coupled to High Resolution Mass Spectrometry in the Pivotal Phase 3 Multiple Myeloma Trial, Icaria-MM

(2019) Greg Finn et al.   BLOOD

An immunocapture-LC-MS-based assay for serum SPINK1 allows simultaneous quantification and detection of SPINK1 variants

(2018) Suvi Ravela et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

LC–HRMS quantitation of intact antibody drug conjugate trastuzumab emtansine from rat plasma

(2018) Wen Jin et al.   Bioanalysis

Perspectives on potentiating immunocapture-LC–MS for the bioanalysis of biotherapeutics and biomarkers

(2018) Hiroshi Sugimoto et al.   Bioanalysis

To elute or not to elute in immunocapture bottom-up LC–MS

(2017) Maren Christin Stillesby Levernæs et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Antibody based affinity capture LC-MS/MS in quantitative determination of proteins in biological matrices

(2017) Trine Grønhaug Halvorsen et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Immunocapture isotope dilution mass spectrometry in response to a pandemic influenza threat

(2017) Carrie L. Pierce et al.   VACCINE

The future of immunocapture-capillary electrophoresis-high resolution mass spectrometry

(2017) Linna Wang et al.   Bioanalysis

Two-Dimensional Liquid Chromatography: A State of the Art Tutorial

(2016) Dwight R. Stoll et al.   ANALYTICAL CHEMISTRY

Vitamin D metabolite profiling using liquid chromatography–tandem mass spectrometry (LC–MS/MS)

(2016) Glenville Jones et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

LC–MS quantification of protein drugs: validating protein LC–MS methods with predigestion immunocapture

(2016) Jeffrey Duggan et al.   Bioanalysis

A workflow for absolute quantitation of large therapeutic proteins in biological samples at intact level using LC-HRMS

(2016) Wenying Jian et al.   Bioanalysis

A whole-molecule immunocapture LC–MS approach for the in vivo quantitation of biotherapeutics

(2016) John F Kellie et al.   Bioanalysis

Techniques for quantitative LC–MS/MS analysis of protein therapeutics: advances in enzyme digestion and immunocapture

(2016) Eliza N Fung et al.   Bioanalysis

Salivary cortisol and cortisone by LC–MS/MS: validation, reference intervals and diagnostic accuracy in Cushing's syndrome

(2015) Giorgia Antonelli et al.   CLINICA CHIMICA ACTA

LC-MS/MS Measurement of Parathyroid Hormone-Related Peptide

(2015) M. M. Kushnir et al.   CLINICAL CHEMISTRY

Immunocapture strategies in translational proteomics

(2015) Claudia Fredolini et al.   Expert Review of Proteomics

Magnetic separation techniques in sample preparation for biological analysis: A review

(2014) Jincan He et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Fundamentals and application of magnetic particles in cell isolation and enrichment: a review

(2014) Brian D Plouffe et al.   REPORTS ON PROGRESS IN PHYSICS

Orbitrap Mass Spectrometry

(2013) Roman A. Zubarev et al.   ANALYTICAL CHEMISTRY

10years of MS instrumental developments – Impact on LC–MS/MS in clinical chemistry

(2011) Markus Himmelsbach   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS

(2011) Ragu Ramanathan et al.   JOURNAL OF MASS SPECTROMETRY

Development of Glycoprotein Capture-Based Label-Free Method for the High-throughput Screening of Differential Glycoproteins in Hepatocellular Carcinoma

(2011) Rui Chen et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantification of Serum 1-84 Parathyroid Hormone in Patients with Hyperparathyroidism by Immunocapture In Situ Digestion Liquid Chromatography-Tandem Mass Spectrometry

(2009) V. Kumar et al.   CLINICAL CHEMISTRY

Immuno-capture as ultimate sample cleanup in LC-MS/MS determination of the early stage biomarker ProGRP

(2009) Bjørn Winther et al.   JOURNAL OF SEPARATION SCIENCE