Nuclear receptor subfamily 1 group D member 1 suppresses the proliferation, migration of adventitial fibroblasts, and vascular intimal hyperplasia via mammalian target of rapamycin complex 1/β-catenin pathway

Caffeine prevents restenosis and inhibits vascular smooth muscle cell proliferation through the induction of autophagy

(2022) Madhulika Tripathi et al.   Autophagy

Inhibition of PIKfyve Ameliorates the Proliferation and Migration of Vascular Smooth Muscle Cells and Vascular Intima Hyperplasia By Reducing mTORC1 Activity

(2022) Min Gu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2

(2022) Ling-Yue Sun et al.   CIRCULATION

Cezanne is a critical regulator of pathological arterial remodelling by targeting β-catenin signalling

(2021) Weiwei An et al.   CARDIOVASCULAR RESEARCH

Circadian Mechanisms in Medicine

(2021) Ravi Allada et al.   NEW ENGLAND JOURNAL OF MEDICINE

P2X7 Receptor–Mediated Inflammation in Cardiovascular Disease

(2021) Junteng Zhou et al.   Frontiers in Pharmacology

NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway

(2021) Huailin Wang et al.   BMC CANCER

Loss of the transcriptional repressor Rev-erbα upregulates metabolism and proliferation in cultured mouse embryonic fibroblasts

(2021) Sean P. Gillis et al.   Scientific Reports

Molecular clock REV-ERBα regulates cigarette smoke–induced pulmonary inflammation and epithelial-mesenchymal transition

(2021) Qixin Wang et al.   JCI Insight

Danlou Tablet Activates Autophagy of Vascular Adventitial Fibroblasts Through PI3K/Akt/mTOR to Protect Cells From Damage Caused by Atherosclerosis

(2021) Li Wang et al.   Frontiers in Pharmacology

Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway

(2021) Qian Lei et al.   Journal of Advanced Research

Decreased expression of Rev-Erbα in the epileptic foci of temporal lobe epilepsy and activation of Rev-Erbα have anti-inflammatory and neuroprotective effects in the pilocarpine model

(2020) Jiong Yue et al.   Journal of Neuroinflammation

P2X7

(2020) Brandon G. Shokoples et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Preventing treatment failures in coronary artery disease: what can we learn from the biology of in-stent restenosis, vein graft failure, and internal thoracic arteries?

(2019) Cristiano Spadaccio et al.   CARDIOVASCULAR RESEARCH

Rev-erbα Inhibits Proliferation and Promotes Apoptosis of Preadipocytes through the Agonist GSK4112

(2019) Guiyan Chu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FSP1 promotes the biofunctions of adventitial fibroblast through the crosstalk among RAGE, JAK2/STAT3 and Wnt3a/β‐catenin signalling pathways

(2019) Caihua Fu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Disruption of circadian rhythm by alternating light‐dark cycles aggravates atherosclerosis development in APOE*3‐Leiden.CETP mice

(2019) Maaike Schilperoort et al.   JOURNAL OF PINEAL RESEARCH

Recent Developments in Vascular Adventitial Pathobiology

(2019) Maria G. Tinajero et al.   AMERICAN JOURNAL OF PATHOLOGY

Activation and Migration of Adventitial Fibroblasts Contributes to Vascular Remodeling

(2018) Xiaowan Han et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade

(2018) Qing-Bo Lu et al.   Redox Biology

Exosome-Mediated Transfer of ACE (Angiotensin-Converting Enzyme) From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promotes Vascular Smooth Muscle Cell Migration

(2018) Ying Tong et al.   HYPERTENSION

Cinnamic aldehyde inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia in Zucker Diabetic Fatty rats

(2018) Nicholas E. Buglak et al.   Redox Biology

Rev-erb agonist improves adverse cardiac remodeling and survival in myocardial infarction through an anti-inflammatory mechanism

(2017) Endin Nokik Stujanna et al.   PLoS One

A crosstalk between TGF-β/Smad3 and Wnt/β-catenin pathways promotes vascular smooth muscle cell proliferation

(2016) Daniel M. DiRenzo et al.   CELLULAR SIGNALLING

Anti-proliferative actions of a synthetic REV-ERBα/β agonist in breast cancer cells

(2015) Yongjun Wang et al.   BIOCHEMICAL PHARMACOLOGY

Kindlin-2 siRNA inhibits vascular smooth muscle cell proliferation, migration and intimal hyperplasia via Wnt signaling

(2015) XIAOLIN WU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

STAT3-mediated MMP-2 expression is required for 15-HETE-induced vascular adventitial fibroblast migration

(2015) Li Zhang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Overexpression of the Circadian Clock GeneRev-erbαAffects Murine Bone Mesenchymal Stem Cell Proliferation and Osteogenesis

(2015) Yao He et al.   STEM CELLS AND DEVELOPMENT

Mammalian Target of Rapamycin Signaling in Cardiac Physiology and Disease

(2014) Sebastiano Sciarretta et al.   CIRCULATION RESEARCH

Carbon monoxide induces chromatin remodelling to facilitate endothelial cell migration

(2014) Mailin Li et al.   THROMBOSIS AND HAEMOSTASIS

SRSF1 and SRSF9 RNA binding proteins promote Wnt signalling-mediated tumorigenesis by enhancing β-catenin biosynthesis

(2013) Yu Fu et al.   EMBO Molecular Medicine

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

(2013) Estelle Woldt et al.   NATURE MEDICINE

Increased Atherosclerotic Lesions in LDL Receptor Deficient Mice With Hematopoietic Nuclear Receptor Rev‐erbα Knock‐ Down

(2013) Hongling Ma et al.   Journal of the American Heart Association