SRSF1 and SRSF9 RNA binding proteins promote Wnt signalling-mediated tumorigenesis by enhancing β-catenin biosynthesis

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

BMP4 Signaling Acts via Dual-Specificity Phosphatase 9 to Control ERK Activity in Mouse Embryonic Stem Cells

(2012) Zhongwei Li et al.   Cell Stem Cell

Drugging Wnt signalling in cancer

(2012) Paul Polakis   EMBO JOURNAL

The many faces and functions of β-catenin

(2012) Tomas Valenta et al.   EMBO JOURNAL

Wnt signaling from membrane to nucleus: β-catenin caught in a loop

(2012) Cara Jamieson et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

SRp20 is a proto-oncogene critical for cell proliferation and tumor induction and maintenance

(2012) Rong Jia et al.   International Journal of Biological Sciences

The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation

(2012) Olga Anczuków et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Protein cross-talk in CD133+ colon cancer cells indicates activation of the Wnt pathway and upregulation of SRp20 that is potentially involved in tumorigenicity

(2012) Claudia Corbo et al.   PROTEOMICS

Wnt/ -Catenin Signaling Regulates Telomerase in Stem Cells and Cancer Cells

(2012) K. Hoffmeyer et al.   SCIENCE

Wnt Signaling, Stem Cells, and Cancer of the Gastrointestinal Tract

(2012) A. Schepers et al.   Cold Spring Harbor Perspectives in Biology

Oncogenic Splicing Factor SRSF1 Is a Critical Transcriptional Target of MYC

(2012) Shipra Das et al.   Cell Reports

How do they do Wnt they do?: regulation of transcription by the Wnt/β-catenin pathway

(2011) H. C. Archbold et al.   Acta Physiologica

Tumor suppressive microRNA-1 mediated novel apoptosis pathways through direct inhibition of splicing factor serine/arginine-rich 9 (SRSF9/SRp30c) in bladder cancer

(2011) Hirofumi Yoshino et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel Synthetic Antagonists of Canonical Wnt Signaling Inhibit Colorectal Cancer Cell Growth

(2011) J. Waaler et al.   CANCER RESEARCH

Shuttling SR proteins: more than splicing factors

(2011) Laure Twyffels et al.   FEBS Journal

Wnt signaling and telomerase activation of hepatoblastoma: correlation with chemosensitivity and surgical resectability

(2011) Yuka Ueda et al.   JOURNAL OF PEDIATRIC SURGERY

Transmembrane Protein 198 Promotes LRP6 Phosphorylation and Wnt Signaling Activation

(2011) J. Liang et al.   MOLECULAR AND CELLULAR BIOLOGY

SRSF1 Regulates the Alternative Splicing of Caspase 9 Via A Novel Intronic Splicing Enhancer Affecting the Chemotherapeutic Sensitivity of Non-Small Cell Lung Cancer Cells

(2011) J. C. Shultz et al.   MOLECULAR CANCER RESEARCH

Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling

(2011) Marina Shkreli et al.   NATURE MEDICINE

A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells

(2011) G Zhu et al.   ONCOGENE

Targeting Wnt Signaling in Colon Cancer Stem Cells

(2010) E. M. F. de Sousa et al.   CLINICAL CANCER RESEARCH

The Oncoprotein SF2/ASF Promotes Non-Small Cell Lung Cancer Survival by Enhancing Survivin Expression

(2010) T. Ezponda et al.   CLINICAL CANCER RESEARCH

A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins)

(2010) J. L. Manley et al.   GENES & DEVELOPMENT

Xenopus Skip Modulates Wnt/β-Catenin Signaling and Functions in Neural Crest Induction

(2010) Ying Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of  -catenin mRNA

(2010) R. K. Bikkavilli et al.   JOURNAL OF CELL SCIENCE

Oncogenic Function of ATDC in Pancreatic Cancer through Wnt Pathway Activation and β-Catenin Stabilization

(2009) Lidong Wang et al.   CANCER CELL

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

RNA-Binding Protein Quaking, a Critical Regulator of Colon Epithelial Differentiation and a Suppressor of Colon Cancer

(2009) Guodong Yang et al.   GASTROENTEROLOGY

A Wnt Survival Guide: From Flies to Human Disease

(2009) Andy J. Chien et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

SR Proteins in Vertical Integration of Gene Expression from Transcription to RNA Processing to Translation

(2009) Xiang-Yang Zhong et al.   MOLECULAR CELL

Evidence that Fold-Change, and Not Absolute Level, of β-Catenin Dictates Wnt Signaling

(2009) Lea Goentoro et al.   MOLECULAR CELL

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

β-Catenin hits chromatin: regulation of Wnt target gene activation

(2009) Christian Mosimann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The SR protein family

(2009) Peter J Shepard et al.   GENOME BIOLOGY

The SR protein family of splicing factors: master regulators of gene expression

(2008) Jennifer C. Long et al.   BIOCHEMICAL JOURNAL

APC Is Essential for Targeting Phosphorylated β-Catenin to the SCFβ-TrCP Ubiquitin Ligase

(2008) YunYun Su et al.   MOLECULAR CELL

The Splicing Factor SF2/ASF Regulates Translation Initiation by Enhancing Phosphorylation of 4E-BP1

(2008) Gracjan Michlewski et al.   MOLECULAR CELL

Kinetics of Wnt-Driven β-Catenin Stabilization Revealed by Quantitative and Temporal Imaging

(2008) Rami N. Hannoush   PLoS One

The splicing-factor oncoprotein SF2/ASF activates mTORC1

(2008) R. Karni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in Apc 716 mice

(2008) T. Fujishita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The  -catenin/TCF4 pathway modifies alternative splicing through modulation of SRp20 expression

(2008) V. Goncalves et al.   RNA