Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation

Circadian rhythm modulates endochondral bone formation via MTR1/AMPKβ1/BMAL1 signaling axis

(2022) Shaoling Yu et al.   CELL DEATH AND DIFFERENTIATION

Light exposure during sleep impairs cardiometabolic function

(2022) Ivy C. Mason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ShcA promotes chondrocyte hypertrophic commitment and osteoarthritis in mice through RunX2 nuclear translocation and YAP1 inactivation

(2022) A. Abou-Jaoude et al.   OSTEOARTHRITIS AND CARTILAGE

Drugging the circadian clock feedback cycle to ameliorate cartilage degeneration

(2022) Ting He et al.   FEBS Journal

Dim light in the evening causes coordinated realignment of circadian rhythms, sleep, and short-term memory

(2021) Shu K. E. Tam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMAL1-Downregulation Aggravates Porphyromonas Gingivalis-Induced Atherosclerosis by Encouraging Oxidative Stress

(2020) Mengru Xie et al.   CIRCULATION RESEARCH

Circadian control of the secretory pathway maintains collagen homeostasis

(2020) Joan Chang et al.   NATURE CELL BIOLOGY

Postnatal Conditional Deletion of Bmal1 in Osteoblasts Enhances Trabecular Bone Formation Via Increased BMP2 Signals

(2020) Zhuang Qian et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A circadian rhythm-gated subcortical pathway for nighttime-light-induced depressive-like behaviors in mice

(2020) Kai An et al.   NATURE NEUROSCIENCE

Circadian Rhythm Protein Bmal1 Modulates Cartilage Gene Expression in Temporomandibular Joint Osteoarthritis via the MAPK/ERK Pathway

(2020) Guokun Chen et al.   Frontiers in Pharmacology

The dark side of nocturnal light pollution. Outdoor light at night increases risk of coronary heart disease

(2020) Thomas Münzel et al.   EUROPEAN HEART JOURNAL

HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

(2019) Steve Stegen et al.   NATURE

Light-exposure at night impairs mouse ovary development via cell apoptosis and DNA damage

(2019) Yapeng Li et al.   BIOSCIENCE REPORTS

Deletion of clock gene Bmal1 impaired the chondrocyte function due to disruption of the HIF1α-VEGF signaling pathway

(2019) Zhengmin Ma et al.   CELL CYCLE

Light-at-night exposure affects brain development through pineal allopregnanolone-dependent mechanisms

(2019) Shogo Haraguchi et al.   eLife

Circadian BMAL1 regulates mandibular condyle development by hedgehog pathway

(2019) Shaoling Yu et al.   CELL PROLIFERATION

Circadian disruption by shifting the light‐dark cycle negatively affects bone health in mice

(2019) Maaike Schilperoort et al.   FASEB JOURNAL

Hormonally mediated effects of artificial light at night on behavior and fitness: linking endocrine mechanisms with function

(2018) Jenny Q. Ouyang et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Systematic review of light exposure impact on human circadian rhythm

(2018) Leena Tähkämö et al.   CHRONOBIOLOGY INTERNATIONAL

P4HA1 mutations cause a unique congenital disorder of connective tissue involving tendon, bone, muscle and the eye

(2017) Yaqun Zou et al.   HUMAN MOLECULAR GENETICS

Melatonin promotes circadian rhythm-induced proliferation through Clock/histone deacetylase 3/c-Myc interaction in mouse adipose tissue

(2017) Zhenjiang Liu et al.   JOURNAL OF PINEAL RESEARCH

Dysregulated circadian rhythm pathway in human osteoarthritis: NR1D1 and BMAL1 suppression alters TGF-β signaling in chondrocytes

(2017) R. Akagi et al.   OSTEOARTHRITIS AND CARTILAGE

Clock GeneBmal1Modulates Human Cartilage Gene Expression by Crosstalk With Sirt1

(2016) Wei Yang et al.   ENDOCRINOLOGY

The Circadian Gene Clock Regulates Bone Formation Via PDIA3

(2016) Gongsheng Yuan et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Epigenetically mediated spontaneous reduction of NFAT1 expression causes imbalanced metabolic activities of articular chondrocytes in aged mice

(2016) M. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE

Circadian physiology of metabolism

(2016) Satchidananda Panda   SCIENCE

The new world atlas of artificial night sky brightness

(2016) F. Falchi et al.   Science Advances

The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity

(2015) Michal Dudek et al.   JOURNAL OF CLINICAL INVESTIGATION

The Effects of Light at Night on Circadian Clocks and Metabolism

(2014) Laura K. Fonken et al.   ENDOCRINE REVIEWS

Stable Isotope-Labeled Collagen: A Novel and Versatile Tool for Quantitative Collagen Analyses Using Mass Spectrometry

(2014) Yuki Taga et al.   JOURNAL OF PROTEOME RESEARCH

Circadian clock control of endocrine factors

(2014) Karen L. Gamble et al.   Nature Reviews Endocrinology

Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at night

(2014) Dawn deHaro et al.   NUCLEIC ACIDS RESEARCH

Light at Night Alters Daily Patterns of Cortisol and Clock Proteins in Female Siberian Hamsters

(2013) T. A. Bedrosian et al.   JOURNAL OF NEUROENDOCRINOLOGY

Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

(2012) N. Huang et al.   SCIENCE

The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks

(2010) Charna Dibner et al.   Annual Review of Physiology

Exposure to Room Light before Bedtime Suppresses Melatonin Onset and Shortens Melatonin Duration in Humans

(2010) Joshua J. Gooley et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Glucocorticoid regulation of the circadian clock modulates glucose homeostasis

(2009) A. Y.-L. So et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nightshift work and fracture risk: the Nurses’ Health Study

(2008) D. Feskanich et al.   OSTEOPOROSIS INTERNATIONAL