Nrf2 silencing amplifies DNA photooxidative damage to activate the STING pathway for synergistic tumor immunotherapy

Mesoporous Calcium Peroxide-Ignited NO Generation for Amplifying Photothermal Immunotherapy of Breast Cancer

(2022) Huisong Hao et al.   CHEMICAL ENGINEERING JOURNAL

Immunogenic cell stress and death

(2022) Guido Kroemer et al.   NATURE IMMUNOLOGY

A Biodegradable Iridium(III) Coordination Polymer for Enhanced Two‐Photon Photodynamic Therapy Using an Apoptosis–Ferroptosis Hybrid Pathway

(2022) Libing Ke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ATP-exhausted nanocomplexes for intratumoral metabolic intervention and photoimmunotherapy

(2022) Mian Yu et al.   BIOMATERIALS

Growth of ZIF-8 Nanoparticles In Situ on Graphene Oxide Nanosheets: A Multifunctional Nanoplatform for Combined Ion-Interference and Photothermal Therapy

(2022) Chunxu Lv et al.   ACS Nano

Light-triggered photodynamic nanomedicines for overcoming localized therapeutic efficacy in cancer treatment

(2022) Jiwoong Choi et al.   ADVANCED DRUG DELIVERY REVIEWS

Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer

(2021) Fang Sun et al.   Advanced Science

Targeting immunogenic cancer cell death by photodynamic therapy: past, present and future

(2021) Razan Alzeibak et al.   Journal for ImmunoTherapy of Cancer

The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING–IFN-β pathway

(2021) Mariko Takahashi et al.   NATURE IMMUNOLOGY

IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer

(2021) Na-Lee Ka et al.   Cell Reports

Gene augmented nuclear-targeting sonodynamic therapy via Nrf2 pathway-based redox balance adjustment boosts peptide-based anti-PD-L1 therapy on colorectal cancer

(2021) Guoyun Wan et al.   JOURNAL OF NANOBIOTECHNOLOGY

Homologous-targeting biomimetic nanoparticles for photothermal therapy and Nrf2-siRNA amplified photodynamic therapy against oral tongue squamous cell carcinoma

(2020) Shurui Shi et al.   CHEMICAL ENGINEERING JOURNAL

Oxidative Stress in Cancer

(2020) John D. Hayes et al.   CANCER CELL

Confined growth of ZIF-8 in dendritic mesoporous organosilica nanoparticles as bio-regulators for enhanced mRNA delivery in vivo

(2020) Yue Wang et al.   National Science Review

Structural basis of STING binding with and phosphorylation by TBK1

(2019) Conggang Zhang et al.   NATURE

Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy

(2019) Anping Li et al.   Journal of Hematology & Oncology

Encapsulation of Plasmid DNA by Nanoscale Metal–Organic Frameworks for Efficient Gene Transportation and Expression

(2019) Yantao Li et al.   ADVANCED MATERIALS

Triggered All-Active Metal Organic Framework: Ferroptosis Machinery Contributes to the Apoptotic Photodynamic Antitumor Therapy

(2019) Xuan Meng et al.   NANO LETTERS

Ginsenosides Rb1 and Rg1 Protect Primary Cultured Astrocytes against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury via Improving Mitochondrial Function

(2019) Meng Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NRF2 and the Hallmarks of Cancer

(2018) Montserrat Rojo de la Vega et al.   CANCER CELL

ROS and the DNA damage response in cancer

(2018) Upadhyayula Sai Srinivas et al.   Redox Biology

Zinc oxide nanoparticles harness autophagy to induce cell death in lung epithelial cells

(2017) Jun Zhang et al.   Cell Death & Disease

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

(2015) Aashiq Hussain Bhat et al.   BIOMEDICINE & PHARMACOTHERAPY

Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies

(2015) Mans Broekgaarden et al.   CANCER AND METASTASIS REVIEWS

In situ vaccination with cowpea mosaic virus nanoparticles suppresses metastatic cancer

(2015) P. H. Lizotte et al.   Nature Nanotechnology

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Potentiates STING-Dependent Immune Sensing

(2013) Nadine Gehrke et al.   IMMUNITY

DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway

(2012) M A Kang et al.   Cell Death & Disease

RNAi-Mediated Silencing of Nuclear Factor Erythroid-2-Related Factor 2 Gene Expression in Non-Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy

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