Gene therapy strategies for glaucoma from IOP reduction to retinal neuroprotection: Progress towards non-viral systems
出版年份 2023 全文链接
标题
Gene therapy strategies for glaucoma from IOP reduction to retinal neuroprotection: Progress towards non-viral systems
作者
关键词
-
出版物
ADVANCED DRUG DELIVERY REVIEWS
Volume 196, Issue -, Pages 114781
出版商
Elsevier BV
发表日期
2023-03-21
DOI
10.1016/j.addr.2023.114781
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Exosome-mediated aptamer S58 reduces fibrosis in a rat glaucoma filtration surgery model
- (2022) Qian-Yi Lin et al. International Journal of Ophthalmology
- From Bench to Bed: The Current Genome Editing Therapies for Glaucoma
- (2022) Meihui He et al. Frontiers in Cell and Developmental Biology
- First hemophilia B gene therapy approved: More than two decades in the making
- (2022) Roland W. Herzog et al. MOLECULAR THERAPY
- Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas
- (2022) Kun Do Rhee et al. Nature Communications
- How could gene therapy change the way we treat age-related macular degeneration?
- (2022) Huma Khan et al. Expert Review of Ophthalmology
- Looking into the future: Gene and cell therapies for glaucoma
- (2021) András M. Komáromy et al. VETERINARY OPHTHALMOLOGY
- Inherited retinal diseases: Therapeutics, clinical trials and end‐points ‐ A review
- (2021) Michalis Georgiou et al. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Proteosomal degradation impairs transcytosis of AAV vectors from suprachoroidal space to retina
- (2021) Kun Ding et al. GENE THERAPY
- Gene therapy in the anterior eye segment
- (2021) Cynthia Amador et al. CURRENT GENE THERAPY
- RNA therapeutics in ophthalmology - translation to clinical trials
- (2021) Aanchal Gupta et al. EXPERIMENTAL EYE RESEARCH
- Use of Gene Therapy in Retinal Ganglion Cell Neuroprotection: Current Concepts and Future Directions
- (2021) Jess Rhee et al. Biomolecules
- A bioinspired synthetic soft hydrogel for the treatment of dry eye
- (2021) Yu Yu et al. Bioengineering & Translational Medicine
- Preservation of vision after CaMKII-mediated protection of retinal ganglion cells
- (2021) Xinzheng Guo et al. CELL
- After Sparring with Payers on Pricing, Bluebird Flies Out of Europe
- (2021) Alex Philippidis HUMAN GENE THERAPY
- In vivo targeted delivery of nucleic acids and CRISPR genome editors enabled by GSH-responsive silica nanoparticles
- (2021) Yuyuan Wang et al. JOURNAL OF CONTROLLED RELEASE
- BCLXL gene therapy moderates neuropathology in the DBA/2J mouse model of inherited glaucoma
- (2021) Ryan J. Donahue et al. Cell Death & Disease
- Long-Term Safety and Tolerability of BMP7 and HGF Gene Overexpression in Rabbit Cornea
- (2021) Suneel Gupta et al. Translational Vision Science & Technology
- Six-Month In Vivo Safety Profiling of Topical Ocular AAV5–Decorin Gene Transfer
- (2021) Rajiv R. Mohan et al. Translational Vision Science & Technology
- Distribution of Gold Nanoparticles in the Anterior Chamber of the Eye after Intracameral Injection for Glaucoma Therapy
- (2021) Tobias Sonntag et al. Pharmaceutics
- mRNA-Based Nanomedicinal Products to Address Corneal Inflammation by Interleukin-10 Supplementation
- (2021) Itziar Gómez-Aguado et al. Pharmaceutics
- The Emerging Role of Topical Ocular Drugs to Target the Posterior Eye
- (2021) Lixiang Wang et al. Ophthalmology and Therapy
- Polydopamine nanoparticles attenuate retina ganglion cell degeneration and restore visual function after optic nerve injury
- (2021) Xiaotong Lou et al. JOURNAL OF NANOBIOTECHNOLOGY
- Evolving Guidelines for Intracameral Injection
- (2020) Jeffrey M. Liebmann et al. JOURNAL OF GLAUCOMA
- Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 Disruption Using CRISPR-Cas9
- (2020) Jiahui Wu et al. MOLECULAR THERAPY
- Immune Responses to Viral Gene Therapy Vectors
- (2020) Jamie L. Shirley et al. MOLECULAR THERAPY
- The biology, function, and biomedical applications of exosomes
- (2020) Raghu Kalluri et al. SCIENCE
- Intravitreal application of AAV-BDNF or mutant AAV-CRMP2 protects retinal ganglion cells and stabilizes axons and myelin after partial optic nerve injury
- (2020) Wissam Chiha et al. EXPERIMENTAL NEUROLOGY
- Progress on ocular siRNA gene‐silencing therapy and drug delivery systems
- (2020) Jinjin Jiang et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Topical siRNA delivery to the cornea and anterior eye by hybrid silicon-lipid nanoparticles
- (2020) Paulina Baran-Rachwalska et al. JOURNAL OF CONTROLLED RELEASE
- Small interfering RNAs (siRNAs) based gene silencing strategies for the treatment of glaucoma: Recent advancements and future perspectives
- (2020) Santoshi Naik et al. LIFE SCIENCES
- Suprachoroidally Delivered DNA Nanoparticles Transfect Retina and Retinal Pigment Epithelium/Choroid in Rabbits
- (2020) Viral S. Kansara et al. Translational Vision Science & Technology
- UMSC-derived exosomes promote retinal ganglion cells survival in a rat model of optic nerve crush
- (2019) Dongyan Pan et al. JOURNAL OF CHEMICAL NEUROANATOMY
- Current management of glaucoma
- (2019) Jed Lusthaus et al. MEDICAL JOURNAL OF AUSTRALIA
- Luxturna: FDA documents reveal the value of a costly gene therapy
- (2019) Jonathan J. Darrow DRUG DISCOVERY TODAY
- Lipid-Based DNA Therapeutics – Hallmarks of Non-Viral Gene Delivery
- (2019) Jonas Buck et al. ACS Nano
- The obstacle course to the inner retina: Hyaluronic acid-coated lipoplexes cross the vitreous but fail to overcome the inner limiting membrane
- (2019) Joke Devoldere et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Development and Clinical Translation of Approved Gene Therapy Products for Genetic Disorders
- (2019) Alireza Shahryari et al. Frontiers in Genetics
- Promising Approach in the Treatment of Glaucoma Using Nanotechnology and Nanomedicine-Based Systems
- (2019) Fidiniaina Rina Juliana et al. MOLECULES
- Therapeutic effects of mesenchymal stem cell-derived exosomes on retinal detachment
- (2019) Mingming Ma et al. EXPERIMENTAL EYE RESEARCH
- Targeted therapy for the post-operative conjunctiva: SPARC silencing reduces collagen deposition
- (2018) Li Fong Seet et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Design of a Novel Gene Therapy Construct to Achieve Sustained Brain-Derived Neurotrophic Factor Signaling in Neurons
- (2018) Andrew Osborne et al. HUMAN GENE THERAPY
- Gene therapy for visual loss: Opportunities and concerns
- (2018) Jia Hui Lee et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Neuroprotection of retinal ganglion cells by a novel gene therapy construct that achieves sustained enhancement of brain-derived neurotrophic factor/tropomyosin-related kinase receptor-B signaling
- (2018) Andrew Osborne et al. Cell Death & Disease
- Addressing the Value of Gene Therapy and Enhancing Patient Access to Transformative Treatments
- (2018) Rachel Salzman et al. MOLECULAR THERAPY
- Intracameral Delivery of Layer‐by‐Layer Coated siRNA Nanoparticles for Glaucoma Therapy
- (2018) Andrea E. Dillinger et al. Small
- A single gene connects stiffness in glaucoma and the vascular system
- (2017) Teresa Borrás EXPERIMENTAL EYE RESEARCH
- Biological aspects of axonal damage in glaucoma: A brief review
- (2017) Ernst R. Tamm et al. EXPERIMENTAL EYE RESEARCH
- Will rising prices and budget constraints prevent patients from accessing novel gene therapies?
- (2017) A Kent et al. GENE THERAPY
- Subretinal Injection: A Review on the Novel Route of Therapeutic Delivery for Vitreoretinal Diseases
- (2017) Yingqian Peng et al. OPHTHALMIC RESEARCH
- CRISPR-Cas9–based treatment of myocilin-associated glaucoma
- (2017) Ankur Jain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Vitamin B 3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice
- (2017) Pete A. Williams et al. SCIENCE
- Bone Marrow-Derived Mesenchymal Stem Cells-Derived Exosomes Promote Survival of Retinal Ganglion Cells Through miRNA-Dependent Mechanisms
- (2017) Ben Mead et al. Stem Cells Translational Medicine
- Application of lipid nanoparticles to ocular drug delivery
- (2016) Luigi Battaglia et al. Expert Opinion on Drug Delivery
- Inducible scAAV2.GRE.MMP1 lowers IOP long-term in a large animal model for steroid-induced glaucoma gene therapy
- (2016) T Borrás et al. GENE THERAPY
- Non-viral gene therapy: Gains and challenges of non-invasive administration methods
- (2016) Marianna Foldvari et al. JOURNAL OF CONTROLLED RELEASE
- The intricacies of neurotrophic factor therapy for retinal ganglion cell rescue in glaucoma: a case for gene therapy
- (2016) Marianna Foldvari et al. Neural Regeneration Research
- Glia–neuron interactions in the mammalian retina
- (2016) Elena Vecino et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Paying for future success in gene therapy
- (2016) S. H. Orkin et al. SCIENCE
- Receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient delivery system for MRTF silencing in conjunctival fibrosis
- (2016) Cynthia Yu-Wai-Man et al. Scientific Reports
- Evaluation of Adenovirus-Mediated Down-Regulation of Connective Tissue Growth Factor on Postoperative Wound Healing After Experimental Glaucoma Surgery
- (2015) Dong Hui Lim et al. CURRENT EYE RESEARCH
- Recent developments in ocular drug delivery
- (2015) Hongming Chen JOURNAL OF DRUG TARGETING
- Neuroprotective therapies in glaucoma: I. Neurotrophic factor delivery
- (2015) Nafiseh Nafissi et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Enhanced survival of retinal ganglion cells is mediated by Müller glial cell-derived PEDF
- (2014) Jan Darius Unterlauft et al. EXPERIMENTAL EYE RESEARCH
- The Pathophysiology and Treatment of Glaucoma
- (2014) Robert N. Weinreb et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration
- (2014) Leah C. Byrne et al. JOURNAL OF CLINICAL INVESTIGATION
- Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: Towards non-invasive glaucoma gene therapy
- (2014) Samih Alqawlaq et al. Nanomedicine-Nanotechnology Biology and Medicine
- Non-viral vectors for gene-based therapy
- (2014) Hao Yin et al. NATURE REVIEWS GENETICS
- Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040
- (2014) Yih-Chung Tham et al. OPHTHALMOLOGY
- Direct Comparison of Administration Routes for AAV8-mediated Ocular Gene Therapy
- (2013) Tsutomu Igarashi et al. CURRENT EYE RESEARCH
- New functions of Müller cells
- (2013) Andreas Reichenbach et al. GLIA
- Phase I Clinical Trial of SYL040012, a Small Interfering RNA Targeting β-Adrenergic Receptor 2, for Lowering Intraocular Pressure
- (2013) Javier Moreno-Montañés et al. MOLECULAR THERAPY
- In Vitro and In Vivo Efficacy of SYL040012, a Novel siRNA Compound for Treatment of Glaucoma
- (2013) Tamara Martínez et al. MOLECULAR THERAPY
- Delivery materials for siRNA therapeutics
- (2013) Rosemary Kanasty et al. NATURE MATERIALS
- Nanomedicines for back of the eye drug delivery, gene delivery, and imaging
- (2013) Uday B. Kompella et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Pre-existing Anti–Adeno-Associated Virus Antibodies as a Challenge in AAV Gene Therapy
- (2013) Vedell Louis Jeune et al. Human Gene Therapy Methods
- Connective Tissue Growth Factor Causes Glaucoma by Modifying the Actin Cytoskeleton of the Trabecular Meshwork
- (2012) Benjamin Junglas et al. AMERICAN JOURNAL OF PATHOLOGY
- Challenges in neuroprotective nanomedicine development: progress towards noninvasive gene therapy of glaucoma
- (2012) Samih Alqawlaq et al. Nanomedicine
- Pigment Epithelium-Derived Factor Released by Müller Glial Cells Exerts Neuroprotective Effects on Retinal Ganglion Cells
- (2012) Jan Darius Unterlauft et al. NEUROCHEMICAL RESEARCH
- Comparative Analysis of DNA Nanoparticles and AAVs for Ocular Gene Delivery
- (2012) Zongchao Han et al. PLoS One
- Gene Transfer Using Micellar Nanovectors Inhibits Corneal Neovascularization In Vivo
- (2011) Aya Iriyama et al. CORNEA
- Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9
- (2011) D Dalkara et al. GENE THERAPY
- The molecular basis of retinal ganglion cell death in glaucoma
- (2011) Mohammadali Almasieh et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Ocular Drug Delivery
- (2010) Ripal Gaudana et al. AAPS Journal
- Neurotrophic factor delivery as a protective treatment for glaucoma
- (2010) Thomas V. Johnson et al. EXPERIMENTAL EYE RESEARCH
- Glaucoma: genes, phenotypes, and new directions for therapy
- (2010) Bao Jian Fan et al. JOURNAL OF CLINICAL INVESTIGATION
- Distal axonopathy with structural persistence in glaucomatous neurodegeneration
- (2010) S. D. Crish et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Applications of nanoparticles in ophthalmology
- (2010) Yolanda Diebold et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Adenovirus-mediated delivery of p27 KIP1 to prevent wound healing after experimental glaucoma filtration surgery
- (2009) Jian-gang Yang et al. ACTA PHARMACOLOGICA SINICA
- Subconjunctival gene delivery of the transcription factor GA-binding protein delays corneal neovascularization in a mouse model
- (2009) K C Yoon et al. GENE THERAPY
- Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV
- (2009) S R Singh et al. GENE THERAPY
- Progress and prospects: immune responses to viral vectors
- (2009) S Nayak et al. GENE THERAPY
- The morphology and spatial arrangement of astrocytes in the optic nerve head of the mouse
- (2009) Daniel Sun et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Recent Perspectives in Ocular Drug Delivery
- (2009) Ripal Gaudana et al. PHARMACEUTICAL RESEARCH
- A Novel Adeno-Associated Viral Variant for Efficient and Selective Intravitreal Transduction of Rat Müller Cells
- (2009) Ryan R. Klimczak et al. PLoS One
- Gemini Surfactants: A New Family of Building Blocks for Non-Viral Gene Delivery Systems
- (2008) Shawn Wettig et al. CURRENT GENE THERAPY
- Extracellular matrix in the trabecular meshwork
- (2008) Ted S. Acott et al. EXPERIMENTAL EYE RESEARCH
- Effects of optic nerve injury, glaucoma, and neuroprotection on the survival, structure, and function of ganglion cells in the mammalian retina
- (2008) A. J. Weber et al. JOURNAL OF PHYSIOLOGY-LONDON
- Investigating the Movement of Intravitreal Human Serum Albumin Nanoparticles in the Vitreous and Retina
- (2008) Hyuncheol Kim et al. PHARMACEUTICAL RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started