CRISPR-Cas9–based treatment of myocilin-associated glaucoma

The many faces of the trabecular meshwork cell

(2017) W. Daniel Stamer et al.   EXPERIMENTAL EYE RESEARCH

In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis Pigmentosa

(2016) Benjamin Bakondi et al.   MOLECULAR THERAPY

Elevation of intraocular pressure in rodents using viral vectors targeting the trabecular meshwork

(2015) Iok-Hou Pang et al.   EXPERIMENTAL EYE RESEARCH

Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing

(2014) Qiurong Ding et al.   CIRCULATION RESEARCH

The Pathophysiology and Treatment of Glaucoma

(2014) Robert N. Weinreb et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype

(2014) Hao Yin et al.   NATURE BIOTECHNOLOGY

Ocular Localization and Transduction by Adenoviral Vectors Are Serotype-Dependent and Can Be Modified by Inclusion of RGD Fiber Modifications

(2014) Kazuhiro Ueyama et al.   PLoS One

The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo

(2014) Su-Ru Lin et al.   Molecular Therapy-Nucleic Acids

Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9

(2013) Yuxuan Wu et al.   Cell Stem Cell

Do Findings on Routine Examination Identify Patients at Risk for Primary Open-Angle Glaucoma?

(2013) Hussein Hollands et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma

(2011) Gulab S. Zode et al.   JOURNAL OF CLINICAL INVESTIGATION

Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice

(2011) Budd A. Tucker et al.   PLoS One

Rescue of Glaucoma-Causing Mutant Myocilin Thermal Stability by Chemical Chaperones

(2010) J. Nicole Burns et al.   ACS Chemical Biology

Overexpression of Myocilin in the Drosophila Eye Activates the Unfolded Protein Response: Implications for Glaucoma

(2009) Mary Anna Carbone et al.   PLoS One