microRNAs as neuroregulators, biomarkers and therapeutic agents in neurodegenerative diseases
出版年份 2015 全文链接
标题
microRNAs as neuroregulators, biomarkers and therapeutic agents in neurodegenerative diseases
作者
关键词
microRNA, Neurodegenerative diseases, Tissue-enriched, Body fluid, Biomarker, Therapeutic agent, microRNA technological advancements
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 73, Issue 4, Pages 811-827
出版商
Springer Nature
发表日期
2015-11-25
DOI
10.1007/s00018-015-2093-x
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways
- (2017) John P. Cogswell et al. JOURNAL OF ALZHEIMERS DISEASE
- Circulatory miR-34a as an RNA-based, noninvasive biomarker for brain aging
- (2016) Xiaoli Li et al. Aging-US
- MicroRNAs and senescence
- (2016) Ivan Martinez et al. Aging-US
- Parkinson's disease and age: The obvious but largely unexplored link
- (2015) Rashed Abdullah et al. EXPERIMENTAL GERONTOLOGY
- Overexpression of blood microRNAs 103a, 30b, and 29a in L-dopa-treated patients with PD
- (2015) A. Serafin et al. NEUROLOGY
- Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells
- (2014) Hua Zhu et al. Autophagy
- Inhibition of miR-34b and miR-34c enhances α-synuclein expression in Parkinson's disease
- (2014) Savan Kabaria et al. FEBS LETTERS
- MiRNA Profile in the Substantia Nigra of Parkinson’s Disease and Healthy Subjects
- (2014) Lucía F. Cardo et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Neuronal Activity-Dependent Regulation of MicroRNAs
- (2014) Su-Eon Sim et al. MOLECULES AND CELLS
- Profiles of Extracellular miRNA in Cerebrospinal Fluid and Serum from Patients with Alzheimer's and Parkinson's Diseases Correlate with Disease Status and Features of Pathology
- (2014) Kasandra Burgos et al. PLoS One
- Identification of circulating microRNAs for the differential diagnosis of Parkinson's disease and Multiple System Atrophy
- (2014) Annamaria Vallelunga et al. Frontiers in Cellular Neuroscience
- MicroRNAs targeting Nicastrin regulate Aβ production and are affected by target site polymorphisms
- (2014) Charlotte Delay et al. Frontiers in Molecular Neuroscience
- Pathogenic microRNA’s in myeloid malignancies
- (2014) Mona Khalaj et al. Frontiers in Genetics
- miR-196a Ameliorates Phenotypes of Huntington Disease in Cell, Transgenic Mouse, and Induced Pluripotent Stem Cell Models
- (2013) Pei-Hsun Cheng et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice
- (2013) Erica D. Koval et al. HUMAN MOLECULAR GENETICS
- Alternative polyadenylation and miR-34 family members regulate tau expression
- (2013) John R. Dickson et al. JOURNAL OF NEUROCHEMISTRY
- Profile of microRNAs in the plasma of Parkinson’s disease patients and healthy controls
- (2013) Lucía F. Cardo et al. JOURNAL OF NEUROLOGY
- An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study
- (2013) Timothy M Miller et al. LANCET NEUROLOGY
- Multiple-to-Multiple Relationships between MicroRNAs and Target Genes in Gastric Cancer
- (2013) Yutaka Hashimoto et al. PLoS One
- Circulating miRNA Biomarkers for Alzheimer's Disease
- (2013) Pavan Kumar et al. PLoS One
- Neuronal dark matter: the emerging role of microRNAs in neurodegeneration
- (2013) Emily F. Goodall et al. Frontiers in Cellular Neuroscience
- Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson's disease
- (2013) L Alvarez-Erviti et al. Cell Death & Disease
- MicroRNA-98 induces an Alzheimer’s disease-like disturbance by targeting insulin-like growth factor 1
- (2013) Yi-Kui Hu et al. Neuroscience Bulletin
- Altered microRNA expression profile in amyotrophic lateral sclerosis: a role in the regulation of NFL mRNA levels
- (2013) Danae Campos-Melo et al. Molecular Brain
- A blood based 12-miRNA signature of Alzheimer disease patients
- (2013) Petra Leidinger et al. GENOME BIOLOGY
- Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes
- (2013) Lilach Soreq et al. Frontiers in Molecular Neuroscience
- Functional Genomics Approach for Identification of Molecular Processes Underlying Neurodegenerative Disorders in Prion Diseases
- (2012) Urmila Basu et al. CURRENT GENOMICS
- Quantitative proteomic strategies for the identification of microRNA targets
- (2012) Chongyang Li et al. Expert Review of Proteomics
- A miRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis
- (2012) Bruna De Felice et al. GENE
- MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein
- (2012) Hyun Jin Cho et al. HUMAN MOLECULAR GENETICS
- miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression
- (2012) D. Yang et al. JOURNAL OF CELL SCIENCE
- Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
- (2012) Oleg Butovsky et al. JOURNAL OF CLINICAL INVESTIGATION
- Selective autophagy degrades DICER and AGO2 and regulates miRNA activity
- (2012) Derrick Gibbings et al. NATURE CELL BIOLOGY
- Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells
- (2012) Shayne A. Bellingham et al. NUCLEIC ACIDS RESEARCH
- ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and microRNA genes from ChIP-Seq data
- (2012) Jian-Hua Yang et al. NUCLEIC ACIDS RESEARCH
- Novel MicroRNAs Differentially Expressed during Aging in the Mouse Brain
- (2012) Sachi Inukai et al. PLoS One
- LC-MS/MS-based shotgun proteomics identified the targets of arthritis-related microRNA
- (2012) Riho Kurata et al. ARTHRITIS RESEARCH & THERAPY
- MicroRNA-277 Modulates the Neurodegeneration Caused by Fragile X Premutation rCGG Repeats
- (2012) Huiping Tan et al. PLoS Genetics
- MicroRNA degradation and turnover: regulating the regulators
- (2012) Zhuo Zhang et al. Wiley Interdisciplinary Reviews-RNA
- MicroRNAs in Common Human Diseases
- (2012) Yu Li et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- MiR-34 modulates Caenorhabditis elegans lifespan via repressing the autophagy gene atg9
- (2011) Jurong Yang et al. AGE
- Non-coding RNAs as regulators of gene expression and epigenetics
- (2011) M. U. Kaikkonen et al. CARDIOVASCULAR RESEARCH
- MicroRNA networks direct neuronal development and plasticity
- (2011) N. F. M. Olde Loohuis et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Blood serum miRNA: Non-invasive biomarkers for Alzheimer's disease
- (2011) Hirosha Geekiyanage et al. EXPERIMENTAL NEUROLOGY
- MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function
- (2011) Elena Miñones-Moyano et al. HUMAN MOLECULAR GENETICS
- Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease
- (2011) Philip Michael Gaughwin et al. HUMAN MOLECULAR GENETICS
- Identification of blood microRNAs associated to Parkinsońs disease
- (2011) Regina Margis et al. JOURNAL OF BIOTECHNOLOGY
- MicroRNA-137/181c Regulates Serine Palmitoyltransferase and In Turn Amyloid , Novel Targets in Sporadic Alzheimer's Disease
- (2011) H. Geekiyanage et al. JOURNAL OF NEUROSCIENCE
- Identification of a MicroRNA that Activates Gene Expression by Repressing Nonsense-Mediated RNA Decay
- (2011) Ivone G. Bruno et al. MOLECULAR CELL
- Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function
- (2011) Charlotte Delay et al. Molecular Neurodegeneration
- Extracellular microRNA: A new source of biomarkers
- (2011) Alton Etheridge et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Experimental strategies for microRNA target identification
- (2011) D. W. Thomson et al. NUCLEIC ACIDS RESEARCH
- Convergence of miRNA Expression Profiling, α-Synuclein Interacton and GWAS in Parkinson's Disease
- (2011) Madalena Martins et al. PLoS One
- The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease
- (2011) Marong Fang et al. TOXICOLOGY LETTERS
- Posttranscriptional Upregulation by MicroRNAs
- (2011) Shobha Vasudevan Wiley Interdisciplinary Reviews-RNA
- Patterns of microRNA expression in normal and early Alzheimer’s disease human temporal cortex: white matter versus gray matter
- (2010) Wang-Xia Wang et al. ACTA NEUROPATHOLOGICA
- miR-107 Regulates Granulin/Progranulin with Implications for Traumatic Brain Injury and Neurodegenerative Disease
- (2010) Wang-Xia Wang et al. AMERICAN JOURNAL OF PATHOLOGY
- MicroRNA-101 downregulates Alzheimer’s amyloid-β precursor protein levels in human cell cultures and is differentially expressed
- (2010) Justin M. Long et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia
- (2010) A. M. Roccaro et al. BLOOD
- Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
- (2010) Markus Hafner et al. CELL
- Altered microRNA regulation in Huntington's disease models
- (2010) Soon-Tae Lee et al. EXPERIMENTAL NEUROLOGY
- Emerging paradigms of regulated microRNA processing
- (2010) M. A. Newman et al. GENES & DEVELOPMENT
- Post-transcriptional Regulation of α-Synuclein Expression by mir-7 and mir-153
- (2010) Epaminondas Doxakis JOURNAL OF BIOLOGICAL CHEMISTRY
- Should the word ‘dementia’ be forgotten?
- (2010) Kurt A. Jellinger JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Global microRNA Expression Profiling of Caenorhabditis elegans Parkinson's Disease Models
- (2010) Suvi Asikainen et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- MicroRNA Regulation of Neural Stem Cells and Neurogenesis
- (2010) Y. Shi et al. JOURNAL OF NEUROSCIENCE
- Posttranscriptional Regulation of MicroRNA Biogenesis in Animals
- (2010) Haruhiko Siomi et al. MOLECULAR CELL
- Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production
- (2010) Keita Miyoshi et al. MOLECULAR GENETICS AND GENOMICS
- Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
- (2010) Stephan Gehrke et al. NATURE
- A novel pathway regulates memory and plasticity via SIRT1 and miR-134
- (2010) Jun Gao et al. NATURE
- Targeting microRNAs in cancer: rationale, strategies and challenges
- (2010) Ramiro Garzon et al. NATURE REVIEWS DRUG DISCOVERY
- Genome-wide analysis of miRNA expression reveals a potential role for miR-144 in brain aging and spinocerebellar ataxia pathogenesis
- (2010) Stephan Persengiev et al. NEUROBIOLOGY OF AGING
- MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice
- (2010) Wei Liu et al. NEUROBIOLOGY OF AGING
- Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3
- (2010) M. Shioya et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Micro RNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation
- (2010) A.I. Pogue et al. NEUROSCIENCE LETTERS
- Increased expression of miRNA-146a in Alzheimer's disease transgenic mouse models
- (2010) Y.Y. Li et al. NEUROSCIENCE LETTERS
- A myriad of miRNA variants in control and Huntington’s disease brain regions detected by massively parallel sequencing
- (2010) Eulàlia Martí et al. NUCLEIC ACIDS RESEARCH
- MicroRNA-Related Cofilin Abnormality in Alzheimer's Disease
- (2010) Jiaqi Yao et al. PLoS One
- miRNA malfunction causes spinal motor neuron disease
- (2010) S. Haramati et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptome and targetome analysis in MIR155 expressing cells using RNA-seq
- (2010) G. Xu et al. RNA
- Reciprocal regulation of microRNA and mRNA profiles in neuronal development and synapse formation
- (2009) Sergei A Manakov et al. BMC GENOMICS
- Posttranscriptional Crossregulation between Drosha and DGCR8
- (2009) Jinju Han et al. CELL
- Origins and Mechanisms of miRNAs and siRNAs
- (2009) Richard W. Carthew et al. CELL
- Editing independent effects of ADARs on the miRNA/siRNA pathways
- (2009) Bret S E Heale et al. EMBO JOURNAL
- The Bifunctional microRNA miR-9/miR-9* Regulates REST and CoREST and Is Downregulated in Huntington's Disease
- (2009) A. N. Packer et al. JOURNAL OF NEUROSCIENCE
- Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease
- (2009) Judith Montag et al. Molecular Neurodegeneration
- Biogenesis of small RNAs in animals
- (2009) V. Narry Kim et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Gene Dysregulation in Huntington’s Disease: REST, MicroRNAs and Beyond
- (2009) Rory Johnson et al. NEUROMOLECULAR MEDICINE
- Ionizing Radiation-Induced Oxidative Stress Alters miRNA Expression
- (2009) Nicole L. Simone et al. PLoS One
- Repression of -synuclein expression and toxicity by microRNA-7
- (2009) E. Junn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Post-transcriptional control of DGCR8 expression by the Microprocessor
- (2009) R. Triboulet et al. RNA
- MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice
- (2009) A. H. Williams et al. SCIENCE
- Variation in the miRNA-433 Binding Site of FGF20 Confers Risk for Parkinson Disease by Overexpression of α-Synuclein
- (2008) Gaofeng Wang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Small-Molecule Inhibitors of MicroRNA miR-21 Function
- (2008) Kiranmai Gumireddy et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
- (2008) Xi Chen et al. CELL RESEARCH
- MicroRNAs in brain function and disease
- (2008) Andreas Walter Kuss et al. Current Neurology and Neuroscience Reports
- Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs
- (2008) J. E. Babiarz et al. GENES & DEVELOPMENT
- Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia
- (2008) Rosa Rademakers et al. HUMAN MOLECULAR GENETICS
- A Human snoRNA with MicroRNA-Like Functions
- (2008) Christine Ender et al. MOLECULAR CELL
- MicroRNAs can regulate human APP levels
- (2008) Neha Patel et al. Molecular Neurodegeneration
- Cancer biomarker profiling with microRNAs
- (2008) Stefanie S Jeffrey NATURE BIOTECHNOLOGY
- MicroRNA regulation of Alzheimer's Amyloid precursor protein expression
- (2008) Sébastien S. Hébert et al. NEUROBIOLOGY OF DISEASE
- Evidence for Selective microRNAs and Their Effectors as Common Long-Term Targets for the Actions of Mood Stabilizers
- (2008) Rulun Zhou et al. NEUROPSYCHOPHARMACOLOGY
- Serum MicroRNAs Are Promising Novel Biomarkers
- (2008) Shlomit Gilad et al. PLoS One
- A miRNA Signature of Prion Induced Neurodegeneration
- (2008) Reuben Saba et al. PLoS One
- Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/ -secretase expression
- (2008) S. S. Hebert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vitro reconstitution of the human RISC-loading complex
- (2008) I. J. MacRae et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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