Melatonin Attenuates Ischemic-like Cell Injury by Promoting Autophagosome Maturation via the Sirt1/FoxO1/Rab7 Axis in Hippocampal HT22 Cells and in Organotypic Cultures

Apelin-36 Protects HT22 Cells Against Oxygen-Glucose Deprivation/Reperfusion-Induced Oxidative Stress and Mitochondrial Dysfunction by Promoting SIRT1-Mediated PINK1/Parkin-Dependent Mitophagy

(2021) Ziqi Shao et al.   NEUROTOXICITY RESEARCH

Melatonin Protects HT22 Hippocampal Cells from H2O2-induced Injury by Increasing Beclin1 and Atg Protein Levels to Activate Autophagy

(2020) Qiang Gao et al.   CURRENT PHARMACEUTICAL DESIGN

Crosstalk Between Autophagy and Cerebral Ischemia

(2019) Yulin Sun et al.   Frontiers in Neuroscience

Modulation of RAB7A Protein Expression Determines Resistance to Cisplatin through Late Endocytic Pathway Impairment and Extracellular Vesicular Secretion

(2019) Flora Guerra et al.   Cancers

Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity

(2019) Arash Latifkar et al.   DEVELOPMENTAL CELL

The FoxO–Autophagy Axis in Health and Disease

(2019) Zhiyong Cheng   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Resveratrol protects neuronal-like cells expressing mutant Huntingtin from dopamine toxicity by rescuing ATG4-mediated autophagosome formation

(2018) Chiara Vidoni et al.   NEUROCHEMISTRY INTERNATIONAL

Rab GTPase Function in Endosome and Lysosome Biogenesis

(2018) Lars Langemeyer et al.   TRENDS IN CELL BIOLOGY

Melatonin Acts in Synergy with Hypothermia to Reduce Oxygen-Glucose Deprivation-Induced Cell Death in Rat Hippocampus Organotypic Slice Cultures

(2018) Silvia Carloni et al.   Neonatology

Revisiting Rab7 Functions in Mammalian Autophagy: Rab7 Knockout Studies

(2018) Yoshihiko Kuchitsu et al.   Cells

Melatonin prevents mitochondrial dysfunction and promotes neuroprotection by inducing autophagy during oxaliplatin-evoked peripheral neuropathy

(2017) Aparna Areti et al.   JOURNAL OF PINEAL RESEARCH

Rapid modulation of the silent information regulator 1 by melatonin after hypoxia-ischemia in the neonatal rat brain

(2017) Silvia Carloni et al.   JOURNAL OF PINEAL RESEARCH

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

(2017) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Autophagosome maturation mediated by Rab7 contributes to neuroprotection of hypoxic preconditioning against global cerebral ischemia in rats

(2017) Lixuan Zhan et al.   Cell Death & Disease

Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation

(2017) Shenglong Cao et al.   Scientific Reports

Melatonin action in tumor skeletal muscle cells: an ultrastructural study

(2016) S. Burattini et al.   ACTA HISTOCHEMICA

The divergent roles of autophagy in ischemia and preconditioning

(2015) Rui Sheng et al.   ACTA PHARMACOLOGICA SINICA

p62/SQSTM1 functions as a signaling hub and an autophagy adaptor

(2015) Yoshinori Katsuragi et al.   FEBS Journal

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

(2015) Lucien C. Manchester et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Ameliorates Arsenite-Induced Neurotoxicity: Involvement of Autophagy and Mitochondria

(2015) Y. C. Teng et al.   MOLECULAR NEUROBIOLOGY

Organotypic brain slice cultures: A review

(2015) C. Humpel   NEUROSCIENCE

The autophagic roles of Rab small GTPases and their upstream regulators

(2014) Zsuzsanna Szatmári et al.   Autophagy

Regulation of autophagy by the Rab GTPase network

(2014) X Ao et al.   CELL DEATH AND DIFFERENTIATION

Melatonin reduces endoplasmic reticulum stress and preserves sirtuin 1 expression in neuronal cells of newborn rats after hypoxia-ischemia

(2014) Silvia Carloni et al.   JOURNAL OF PINEAL RESEARCH

GTPase Networks in Membrane Traffic

(2012) Emi Mizuno-Yamasaki et al.   Annual Review of Biochemistry

Maturation of autophagosomes and endosomes: A key role for Rab7

(2012) Juha M.T. Hyttinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes

(2012) Eisuke Itakura et al.   CELL

Impaired Autophagosome Clearance Contributes to Cardiomyocyte Death in Ischemia/Reperfusion Injury

(2012) Xiucui Ma et al.   CIRCULATION

Mechanisms of Autophagosome Biogenesis

(2012) David C. Rubinsztein et al.   CURRENT BIOLOGY

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway

(2011) Angeles Duran et al.   MOLECULAR CELL

Role of Rab GTPases in Membrane Traffic and Cell Physiology

(2011) Alex H. Hutagalung et al.   PHYSIOLOGICAL REVIEWS

Organotypic Hippocampal Slice Cultures

(2011) Ximena Opitz-Araya et al.   Jove-Journal of Visualized Experiments

Tethering Factors as Organizers of Intracellular Vesicular Traffic

(2010) I-Mei Yu et al.   Annual Review of Cell and Developmental Biology

Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia

(2010) Silvia Carloni et al.   Autophagy

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combinational Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor Proteins VAMP8 and Vti1b Mediate Fusion of Antimicrobial and Canonical Autophagosomes with Lysosomes

(2010) Nobumichi Furuta et al.   MOLECULAR BIOLOGY OF THE CELL

IGF-I stimulates Rab7-RILP interaction during neuronal autophagy

(2010) Mona Bains et al.   NEUROSCIENCE LETTERS

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Autophagosome formation in mammalian cells

(2010) Chloe Burman et al.   Seminars in Immunopathology

Vps-C complexes: gatekeepers of endolysosomal traffic

(2009) Daniel P Nickerson et al.   CURRENT OPINION IN CELL BIOLOGY

Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology

(2008) Anne M. Cataldo et al.   AMERICAN JOURNAL OF PATHOLOGY

Membrane traffic in the secretory pathway

(2008) M. Fukuda   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional Characterization of Rab7 Mutant Proteins Associated with Charcot-Marie-Tooth Type 2B Disease

(2008) M. R. Spinosa et al.   JOURNAL OF NEUROSCIENCE

Protective role of autophagy in neonatal hypoxia–ischemia induced brain injury

(2008) Silvia Carloni et al.   NEUROBIOLOGY OF DISEASE

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA