Construction of a pancreatic cancer nerve invasion system using brain and pancreatic cancer organoids

Perineural Invasion in Pancreatic Ductal Adenocarcinoma (PDAC): A Saboteur of Curative Intended Therapies?

(2022) Matthäus Felsenstein et al.   Journal of Clinical Medicine

Neuroinvasion of SARS-CoV-2 in human and mouse brain

(2021) Eric Song et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neurodegenerative Disease and the NLRP3 Inflammasome

(2021) Jonathan A. Holbrook et al.   Frontiers in Pharmacology

Advances in development and application of human organoids

(2021) Abhijith Shankaran et al.   3 Biotech

Investigation of Neural Microenvironment in Prostate Cancer in Context of Neural Density, Perineural Invasion, and Neuroendocrine Profile of Tumors

(2021) Dawid Sigorski et al.   Frontiers in Oncology

Cellular and molecular mechanisms of perineural invasion of pancreatic ductal adenocarcinoma

(2021) Jingbo Li et al.   Cancer Communications

Human neural organoids: Models for developmental neurobiology and disease

(2021) Brian Guy et al.   DEVELOPMENTAL BIOLOGY

Pathogenesis and Treatment of Pancreatic Cancer Related Pain

(2020) INES LOHSE et al.   ANTICANCER RESEARCH

CXCL10 and CCL21 Promote Migration of Pancreatic Cancer Cells Toward Sensory Neurons and Neural Remodeling in Tumors in Mice, Associated With Pain in Patients

(2020) Michael Hirth et al.   GASTROENTEROLOGY

Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics

(2020) Teresa G Krieger et al.   NEURO-ONCOLOGY

Regeneration using endogenous neural stem cells following neonatal brain injury

(2020) Hideo Jinno   PEDIATRICS INTERNATIONAL

Brainstem Organoids From Human Pluripotent Stem Cells

(2020) Nobuyuki Eura et al.   Frontiers in Neuroscience

Traumatic brain injury and hippocampal neurogenesis: Functional implications

(2020) John B. Redell et al.   EXPERIMENTAL NEUROLOGY

Cancer-associated neurogenesis and nerve-cancer crosstalk

(2020) Deborah A Silverman et al.   CANCER RESEARCH

Basal microvilli define the metabolic capacity and lethal phenotype of pancreatic cancer

(2020) Xu Han et al.   JOURNAL OF PATHOLOGY

hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids

(2019) Yangfei Xiang et al.   Cell Stem Cell

Brain organoids: advances, applications and challenges

(2019) Xuyu Qian et al.   DEVELOPMENT

Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice

(2019) Noelle R. Jurcak et al.   GASTROENTEROLOGY

Insult-induced aberrant hippocampal neurogenesis: Functional consequences and possible therapeutic strategies

(2019) P. Bielefeld et al.   BEHAVIOURAL BRAIN RESEARCH

Congenital pituitary hypoplasia model demonstrates hypothalamic OTX2 regulation of pituitary progenitor cells

(2019) Ryusaku Matsumoto et al.   JOURNAL OF CLINICAL INVESTIGATION

Non–small-cell Lung Cancer With Brain Metastasis at Presentation

(2018) Saiama N. Waqar et al.   Clinical Lung Cancer

Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy

(2018) Jin Hui Hor et al.   Cell Death & Disease

Enzyme and Chemical Assisted N-Terminal Blocked Peptides Analysis, ENCHANT, as a Selective Proteomics Approach Complementary to Conventional Shotgun Approach

(2017) Jingnan Huang et al.   JOURNAL OF PROTEOME RESEARCH

Activation of NLRP3 inflammasome in peripheral nerve contributes to paclitaxel-induced neuropathic pain

(2017) Min Jia et al.   Molecular Pain

Assembly of functionally integrated human forebrain spheroids

(2017) Fikri Birey et al.   NATURE

BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity

(2017) Hexige Saiyin et al.   Oncotarget

Sevoflurane preconditioning induced endogenous neurogenesis against ischemic brain injury by promoting microglial activation

(2017) Li Li et al.   Oncotarget

Ganglion blocks as a treatment of pain: current perspectives

(2017) Osman Hakan Gunduz et al.   Journal of Pain Research

The tumor as an organ: comprehensive spatial and temporal modeling of the tumor and its microenvironment

(2016) Naamah Bloch et al.   BMC BIOINFORMATICS

Inhibition of NF-kappa B pathway leads to deregulation of epithelial–mesenchymal transition and neural invasion in pancreatic cancer

(2016) Alice Nomura et al.   LABORATORY INVESTIGATION

IL-8–Positive Tumor-Infiltrating Inflammatory Cells Are a Novel Prognostic Marker in Pancreatic Ductal Adenocarcinoma Patients

(2016) Yuan Fang et al.   PANCREAS

Retinal Organoids from Pluripotent Stem Cells Efficiently Recapitulate Retinogenesis

(2016) Manuela Völkner et al.   Stem Cell Reports

Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein

(2015) J. J. Kamphorst et al.   CANCER RESEARCH

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

(2015) Sylvia F. Boj et al.   CELL

Identification of novel vascular projections with cellular trafficking abilities on the microvasculature of pancreatic ductal adenocarcinoma

(2015) Hexige Saiyin et al.   JOURNAL OF PATHOLOGY

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

(2015) Minoru Takasato et al.   NATURE

Neural plasticity in pancreatitis and pancreatic cancer

(2015) Ihsan Ekin Demir et al.   Nature Reviews Gastroenterology & Hepatology

Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue

(2015) Hideya Sakaguchi et al.   Nature Communications

Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells

(2015) Keiko Muguruma et al.   Cell Reports

An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts

(2014) Nicholas Bredenkamp et al.   NATURE CELL BIOLOGY

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

Brain Metastasis in Pancreatic Cancer

(2013) Johannes Lemke et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

(2013) Cosimo Commisso et al.   NATURE

Vascularized and functional human liver from an iPSC-derived organ bud transplant

(2013) Takanori Takebe et al.   NATURE

Efficient generation of lung and airway epithelial cells from human pluripotent stem cells

(2013) Sarah X L Huang et al.   NATURE BIOTECHNOLOGY

Self-organizing optic-cup morphogenesis in three-dimensional culture

(2011) Mototsugu Eiraku et al.   NATURE

Multiple uses of basement membrane-like matrix (BME/Matrigel) in vitro and in vivo with cancer cells

(2010) Gabriel Benton et al.   INTERNATIONAL JOURNAL OF CANCER

Neural Invasion in Pancreatic Cancer: The Past, Present and Future

(2010) Ihsan Ekin Demir et al.   Cancers

The microenvironment in chronic pancreatitis and pancreatic cancer induces neuronal plasticity

(2009) i. e. demir et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Neural invasion in pancreatic cancer: A mutual tropism between neurons and cancer cells

(2008) Güralp O. Ceyhan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

(2008) Mototsugu Eiraku et al.   Cell Stem Cell