USP7 regulates the ncPRC1 Polycomb axis to stimulate genomic H2AK119ub1 deposition uncoupled from H3K27me3
出版年份 2022 全文链接
标题
USP7 regulates the ncPRC1 Polycomb axis to stimulate genomic H2AK119ub1 deposition uncoupled from H3K27me3
作者
关键词
-
出版物
Science Advances
Volume 8, Issue 44, Pages -
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2022-11-05
DOI
10.1126/sciadv.abq7598
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Polycomb group ring finger protein 6 suppresses Myc-induced lymphomagenesis
- (2022) Nina Tanaskovic et al. Life Science Alliance
- Positional cloning and comprehensive mutation analysis identified a novel KDM2B mutation in a Japanese family with minor malformations, intellectual disability, and schizophrenia
- (2021) Saeko Yokotsuka-Ishida et al. JOURNAL OF HUMAN GENETICS
- JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications
- (2021) Vignesh Kasinath et al. SCIENCE
- Polycomb complexes redundantly maintain epidermal stem cell identity during development
- (2021) Idan Cohen et al. GENES & DEVELOPMENT
- Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL)
- (2021) Timothy I. Shaw et al. Scientific Reports
- The roles of Polycomb repressive complexes in mammalian development and cancer
- (2021) Andrea Piunti et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis
- (2021) Dongxue Su et al. NUCLEIC ACIDS RESEARCH
- The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia
- (2021) Henny Maat et al. iScience
- Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability
- (2021) Marit E. Geijer et al. NATURE CELL BIOLOGY
- Polycomb-dependent histone H2A ubiquitination links developmental disorders with cancer
- (2021) Simone Tamburri et al. TRENDS IN GENETICS
- Time-resolved in vivo ubiquitinome profiling by DIA-MS reveals USP7 targets on a proteome-wide scale
- (2021) Martin Steger et al. Nature Communications
- Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness
- (2021) Haritha Mathsyaraja et al. eLife
- Recent advances in the development of ubiquitin-specific-processing protease 7 (USP7) inhibitors
- (2020) Peng Li et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Parallel PRC2/cPRC1 and vPRC1 pathways silence lineage-specific genes and maintain self-renewal in mouse embryonic stem cells
- (2020) J. A. Zepeda-Martinez et al. Science Advances
- OFCD syndrome and extraembryonic defects are revealed by conditional mutation of the polycomb-group repressive complex 1.1 (PRC1.1) gene BCOR
- (2020) Michelle Y. Hamline et al. DEVELOPMENTAL BIOLOGY
- USP7 manipulation by viral proteins
- (2020) Anna Bojagora et al. VIRUS RESEARCH
- Pathogenic variants in USP7 cause a neurodevelopmental disorder with speech delays, altered behavior, and neurologic anomalies
- (2019) Michael D. Fountain et al. GENETICS IN MEDICINE
- Dangerous liaisons: interplay between SWI/SNF, NuRD, and Polycomb in chromatin regulation and cancer
- (2019) Adrian P. Bracken et al. GENES & DEVELOPMENT
- PRC2 is high maintenance
- (2019) Jia-Ray Yu et al. GENES & DEVELOPMENT
- Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities
- (2019) Andrea Scelfo et al. MOLECULAR CELL
- Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression
- (2019) Nadezda A. Fursova et al. MOLECULAR CELL
- The long non-coding RNA H19: an active player with multiple facets to sustain the hallmarks of cancer
- (2019) Clément Lecerf et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease
- (2019) Radhika Rawat et al. CURRENT OPINION IN CELL BIOLOGY
- BCOR involvement in cancer
- (2019) Annalisa Astolfi et al. Epigenomics
- Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma
- (2019) Paula Llabata et al. MOLECULAR CANCER RESEARCH
- Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression
- (2019) Simone Tamburri et al. MOLECULAR CELL
- PRC1 Catalytic Activity Is Central to Polycomb System Function
- (2019) Neil P. Blackledge et al. MOLECULAR CELL
- De novo mutation inRING1with epigenetic effects on neurodevelopment
- (2018) Sarah B. Pierce et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6
- (2018) Bastian Stielow et al. PLoS Genetics
- Identification and Characterization of USP7 Targets in Cancer Cells
- (2018) Anna Georges et al. Scientific Reports
- The MYC transcription factor network: balancing metabolism, proliferation and oncogenesis
- (2018) Patrick A. Carroll et al. Frontiers of Medicine
- Regulation of USP7: A High Incidence of E3 Complexes
- (2017) Robbert Q. Kim et al. JOURNAL OF MOLECULAR BIOLOGY
- PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes
- (2017) Mitsuhiro Endoh et al. eLife
- Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity
- (2016) Fulvio Chiacchiera et al. Cell Stem Cell
- EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape
- (2016) Robert Liefke et al. MOLECULAR CELL
- A High-Density Map for Navigating the Human Polycomb Complexome
- (2016) Simon Hauri et al. Cell Reports
- Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice
- (2016) A. Rossi et al. Science Advances
- Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation
- (2015) Ana Raquel Pengelly et al. GENES & DEVELOPMENT
- USP7 Cooperates with SCML2 To Regulate the Activity of PRC1
- (2015) Emilio Lecona et al. MOLECULAR AND CELLULAR BIOLOGY
- USP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental Disorder
- (2015) Yi-Heng Hao et al. MOLECULAR CELL
- Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation
- (2014) Neil P. Blackledge et al. CELL
- Nucleotide Biosynthetic Enzyme GMP Synthase Is a TRIM21-Controlled Relay of p53 Stabilization
- (2014) B. Ashok Reddy et al. MOLECULAR CELL
- An AUTS2–Polycomb complex activates gene expression in the CNS
- (2014) Zhonghua Gao et al. NATURE
- Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease
- (2014) Yuming Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome
- (2014) David A. Orlando et al. Cell Reports
- SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing
- (2013) Kyoichi Isono et al. DEVELOPMENTAL CELL
- Fbxl10/Kdm2b Recruits Polycomb Repressive Complex 1 to CpG Islands and Regulates H2A Ubiquitylation
- (2013) Xudong Wu et al. MOLECULAR CELL
- Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes
- (2013) Jin He et al. NATURE CELL BIOLOGY
- A Histone Mutant Reproduces the Phenotype Caused by Loss of Histone-Modifying Factor Polycomb
- (2013) A. R. Pengelly et al. SCIENCE
- RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3
- (2012) Lígia Tavares et al. CELL
- PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes
- (2012) Zhonghua Gao et al. MOLECULAR CELL
- KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands
- (2012) Anca M Farcas et al. eLife
- Mechanism of USP7/HAUSP Activation by Its C-Terminal Ubiquitin-like Domain and Allosteric Regulation by GMP-Synthetase
- (2011) Alex C. Faesen et al. MOLECULAR CELL
- Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor
- (2010) Goedele N Maertens et al. EMBO JOURNAL
- Polycomb complexes act redundantly to repress genomic repeats and genes
- (2010) M. Leeb et al. GENES & DEVELOPMENT
- Biosynthetic Enzyme GMP Synthetase Cooperates with Ubiquitin-Specific Protease 7 in Transcriptional Regulation of Ecdysteroid Target Genes
- (2009) J. A. van der Knaap et al. MOLECULAR AND CELLULAR BIOLOGY
- Inactivation of HAUSP in vivo modulates p53 function
- (2009) N Kon et al. ONCOGENE
- dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing
- (2008) A. Lagarou et al. GENES & DEVELOPMENT
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