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Citrus limon L. (lemon) seed extract shows neuro-modulatory activity in an in vivo thiopental-sodium sleep model by reducing the sleep onset and enhancing the sleep duration

(2022) Md. Mominur Rahman et al.   Journal of Integrative Neuroscience

Applications of Phyto-Nanotechnology for the Treatment of Neurodegenerative Disorders

(2022) Tanima Bhattacharya et al.   Materials

Ginsenosides in Panax genus and their biosynthesis

(2021) Maoqi Hou et al.   Acta Pharmaceutica Sinica B

Preclinical systematic review of ginsenoside Rg1 for cognitive impairment in Alzheimer’s disease

(2021) Hai-Yong Liang et al.   Aging-US

Direct infusion–tandem mass spectrometry combining with data mining strategies enables rapid chemome characterization of medicinal plants: A case study of Polygala tenuifolia

(2021) Ting Li et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A review on advances of treatment modalities for Alzheimer's disease

(2021) Ewen Se Thoe et al.   LIFE SCIENCES

Ginsenoside Re exhibits neuroprotective effects by inhibiting neuroinflammation via CAMK/MAPK/NF‑κB signaling in microglia

(2021) Iskander Madhi et al.   Molecular Medicine Reports

Impact of ginseng on neurotoxicity induced by cisplatin in rats

(2021) Mohamed Hussien et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Ginsenoside Rd Attenuates Tau Phosphorylation in Olfactory Bulb, Spinal Cord, and Telencephalon by Regulating Glycogen Synthase Kinase 3β and Cyclin-Dependent Kinase 5

(2021) Ling Li et al.   Evidence-based Complementary and Alternative Medicine

Rapid Identification of 3,6′-Disinapoyl Sucrose Metabolites in Alzheimer’s Disease Model Mice Using UHPLC–Orbitrap Mass Spectrometry

(2021) Jiaqi Yuan et al.   MOLECULES

Chemical constituents from the aerial part of Polygala tenuifolia

(2021) Yan-Gang Cheng et al.   NATURAL PRODUCT RESEARCH

Network Pharmacology-Based and Molecular Docking-Based Analysis of Suanzaoren Decoction for the Treatment of Parkinson’s Disease with Sleep Disorder

(2021) Yan-yun Liu et al.   Biomed Research International

Extraction optimization of accelerated solvent extraction for eight active compounds from Yaobitong capsule using response surface methodology: Comparison with ultrasonic and reflux extraction

(2020) Yinghe Ji et al.   JOURNAL OF CHROMATOGRAPHY A

Tenuifolin Attenuates Amyloid-β42-Induced Neuroinflammation in Microglia Through the NF-κB Signaling Pathway

(2020) Shuoqi Chen et al.   JOURNAL OF ALZHEIMERS DISEASE

Interaction effect of Alzheimer's disease pathology and education, occupation, and socioeconomic status as a proxy for cognitive reserve on cognitive performance: in vivo positron emission tomography study

(2020) Fumihiko Yasuno et al.   Psychogeriatrics

PC12 Cell Line: Cell Types, Coating of Culture Vessels, Differentiation and Other Culture Conditions

(2020) Benita Wiatrak et al.   Cells

Changes of Ginsenoside Composition in the Creation of Black Ginseng Leaf

(2020) Wei Chen et al.   MOLECULES

Traditional Chinese medicine for anti-Alzheimer’s disease: berberine and evodiamine from Evodia rutaecarpa

(2020) Zhiling Fang et al.   Chinese Medicine

Localization of constituents for determining the age and parts of ginseng through ultraperfomance liquid chromatography quadrupole/time of flight-mass spectrometry combined with desorption electrospray ionization mass spectrometry imaging

(2020) Yuangui Yang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

(2020) Ji-Yeun Hur et al.   NATURE

Extract of the Aerial Part of Polygala tenuifolia Attenuates d-Galactose/NaNO2-induced Learning and Memory Impairment in Mice

(2020) Dian Zhang et al.   PLANTA MEDICA

Panax ginseng components and the pathogenesis of Alzheimer's disease (Review)

(2019) Mayya Razgonova et al.   Molecular Medicine Reports

Effects of different substrates on low-temperature storage of fresh ginseng

(2019) Kun Gao et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Chemical Structures and Pharmacological Profiles of Ginseng Saponins

(2019) Ze-Yu Shi et al.   MOLECULES

Protective effect of Tenuifolin against Alzheimer’s disease

(2019) Lin Wang et al.   NEUROSCIENCE LETTERS

Herbal Compatibility of Ginseng and Rhubarb Exerts Synergistic Neuroprotection in Cerebral Ischemia/Reperfusion Injury of Rats

(2019) Wen-Ting Yang et al.   Frontiers in Physiology

Neuroprotective Effects of Ginsenoside Rf on Amyloid-β-Induced Neurotoxicity in vitro and in vivo

(2018) Yehong Du et al.   JOURNAL OF ALZHEIMERS DISEASE

Optimization of dynamic-microwave assisted enzymatic hydrolysis extraction of total ginsenosides from stems and leaves of panax ginseng by response surface methodology

(2018) Xiao-yan Wang et al.   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

Therapeutic potential of Panax ginseng and its constituents, ginsenosides and gintonin, in neurological and neurodegenerative disorders: a patent review

(2018) Arezoo Rajabian et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

UPLC-QTOF/MS-Based Nontargeted Metabolomic Analysis of Mountain- and Garden-Cultivated Ginseng of Different Ages in Northeast China

(2018) Hailin Zhu et al.   MOLECULES

Putative multiple reaction monitoring strategy for the comparative pharmacokinetics of postoral administration Renshen–Yuanzhi compatibility through liquid chromatography–tandem mass spectrometry

(2018) Yufei Sun et al.   Journal of Ginseng Research

Panax ginseng and Panax quinquefolius : From pharmacology to toxicology

(2017) Cesare Mancuso et al.   FOOD AND CHEMICAL TOXICOLOGY

Lentivirus-mediated interleukin-1β (IL-1β) knock-down in the hippocampus alleviates lipopolysaccharide (LPS)-induced memory deficits and anxiety- and depression-like behaviors in mice

(2017) Mengmeng Li et al.   Journal of Neuroinflammation

Molecular Networking As a Drug Discovery, Drug Metabolism, and Precision Medicine Strategy

(2017) Robert A. Quinn et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Identification of key structural features of the elusive Cu–Aβ complex that generates ROS in Alzheimer’s disease

(2017) Clémence Cheignon et al.   Chemical Science

Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders

(2016) Md. Torequl Islam   NEUROLOGICAL RESEARCH

Effect of Korean Red Ginseng extraction conditions on antioxidant activity, extraction yield, and ginsenoside Rg1 and phenolic content: optimization using response surface methodology

(2016) Jin Woo Lee et al.   Journal of Ginseng Research

Protective effects of ginsenosides Rg1 and Rb1 on an Alzheimer's disease mouse model: A metabolomics study

(2015) Naijing Li et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Identification of ginsenoside markers from dry purified extract of Panax ginseng by a dereplication approach and UPLC–QTOF/MS analysis

(2015) Heejung Yang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins

(2015) An-Guo Wu et al.   Scientific Reports

A Pharmacognostic Approach to the Polygala Genus: Phytochemical and Pharmacological Aspects

(2012) Luiz Carlos Klein Júnior et al.   CHEMISTRY & BIODIVERSITY

Diagnostic ion filtering to characterize ginseng saponins by rapid liquid chromatography with time-of-flight mass spectrometry

(2012) Lian-Wen Qi et al.   JOURNAL OF CHROMATOGRAPHY A