Deep proteome profiling reveals signatures of age and sex differences in paw skin and sciatic nerve of naïve mice

Development of behavioral patterns in young C57BL/6J mice: a home cage-based study

(2022) Maria Reiber et al.   Scientific Reports

Single-cell analysis implicates Th17 to Th2 cell plasticity in the pathogenesis of palmoplantar pustulosis

(2022) Daniel McCluskey et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation

(2022) Andreas‐David Brunner et al.   Molecular Systems Biology

Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease

(2021) Andrew A. Crawford et al.   JOURNAL OF HUMAN GENETICS

The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice

(2021) Alexander S. Häusl et al.   MOLECULAR PSYCHIATRY

Investigation of Neuropathology after Nerve Release in Chronic Constriction Injury of Rat Sciatic Nerve

(2021) Szu-Han Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A ligand-receptor interactome platform for discovery of pain mechanisms and therapeutic targets

(2021) Andi Wangzhou et al.   Science Signaling

Proteome Profile of Myelin in the Zebrafish Brain

(2021) Sophie B. Siems et al.   Frontiers in Cell and Developmental Biology

Vesicular hand eczema transcriptome analysis provides insights into its pathophysiology

(2021) Angelique N. Voorberg et al.   EXPERIMENTAL DERMATOLOGY

Ultrafast and Reproducible Proteomics from Small Amounts of Heart Tissue Enabled by Azo and timsTOF Pro

(2021) Timothy J. Aballo et al.   JOURNAL OF PROTEOME RESEARCH

Extensive and Accurate Benchmarking of DIA Acquisition Methods and Software Tools Using a Complex Proteomic Standard

(2021) Clarisse Gotti et al.   JOURNAL OF PROTEOME RESEARCH

A combined approach for single-cell mRNA and intracellular protein expression analysis

(2021) Johan Reimegård et al.   Communications Biology

Reporting and misreporting of sex differences in the biological sciences

(2021) Yesenia Garcia-Sifuentes et al.   eLife

Proteome profile of peripheral myelin in healthy mice and in a neuropathy model

(2020) Sophie B Siems et al.   eLife

Mitochondria in skin health, aging, and disease

(2020) Annapoorna Sreedhar et al.   Cell Death & Disease

Maturational Changes in Mouse Cutaneous Touch and Piezo2-Mediated Mechanotransduction

(2020) Niklas Michel et al.   Cell Reports

Keratinocytes contribute to normal cold and heat sensation

(2020) Katelyn E Sadler et al.   eLife

A 10-year follow-up study of sex inclusion in the biological sciences

(2020) Nicole C Woitowich et al.   eLife

Schwann Cell Cultures: Biology, Technology and Therapeutics

(2020) Paula V. Monje   Cells

The impact of sex on gene expression across human tissues

(2020) Meritxell Oliva et al.   SCIENCE

Transcriptomic sex differences in sensory neuronal populations of mice

(2020) Jennifer Mecklenburg et al.   Scientific Reports

diaPASEF: parallel accumulation–serial fragmentation combined with data-independent acquisition

(2020) Florian Meier et al.   NATURE METHODS

Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement

(2020) Ashley L Kalinski et al.   eLife

Transcriptome Analysis of the Human Tibial Nerve Identifies Sexually Dimorphic Expression of Genes Involved in Pain, Inflammation, and Neuro-Immunity

(2019) Pradipta R. Ray et al.   Frontiers in Molecular Neuroscience

The Role of Interleukin 6 During Viral Infections

(2019) Lauro Velazquez-Salinas et al.   Frontiers in Microbiology

Role of prolyl hydroxylation in the molecular interactions of collagens

(2019) Pekka Rappu et al.   Essays in Biochemistry

Deep Sequencing of Somatosensory Neurons Reveals Molecular Determinants of Intrinsic Physiological Properties

(2019) Yang Zheng et al.   NEURON

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

(2019) Frank Koopmans et al.   NEURON

pathfindR: An R Package for Comprehensive Identification of Enriched Pathways in Omics Data Through Active Subnetworks

(2019) Ege Ulgen et al.   Frontiers in Genetics

DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput

(2019) Vadim Demichev et al.   NATURE METHODS

SOD1 in Amyotrophic Lateral Sclerosis: “Ambivalent” Behavior Connected to the Disease

(2018) Orietta Pansarasa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons

(2018) Pratibha Narayanan et al.   eLife

Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling

(2018) Francie Moehring et al.   eLife

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

A functional riboSNitch in the 3′UTR ofFKBP5alters microRNA-320a binding efficiency and mediates vulnerability to chronic posttraumatic pain

(2018) Sarah D. Linnstaedt et al.   JOURNAL OF NEUROSCIENCE

Data‐independent acquisition‐based SWATH‐MS for quantitative proteomics: a tutorial

(2018) Christina Ludwig et al.   Molecular Systems Biology

RNA-seq and flow-cytometry of conventional, scalp, and palmoplantar psoriasis reveal shared and distinct molecular pathways

(2018) Richard Ahn et al.   Scientific Reports

Region-Resolved Quantitative Proteome Profiling Reveals Molecular Dynamics Associated With Chronic Pain in the PNS and Spinal Cord

(2018) Allison M. Barry et al.   Frontiers in Molecular Neuroscience

Online Parallel Accumulation–Serial Fragmentation (PASEF) with a Novel Trapped Ion Mobility Mass Spectrometer

(2018) Florian Meier et al.   MOLECULAR & CELLULAR PROTEOMICS

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments

(2018) Christopher S. Hughes et al.   Nature Protocols

Vti1b promotes TRPV1 sensitization during inflammatory pain

(2018) Julia R. Sondermann et al.   PAIN

Dorsal Root Ganglia Isolation and Primary Culture to Study Neurotransmitter Release

(2018) Ya-Tin Lin et al.   Jove-Journal of Visualized Experiments

Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging

(2017) Joerg Isensee et al.   JOURNAL OF CELL SCIENCE

Ectodomain shedding of Limbic System-Associated Membrane Protein (LSAMP) by ADAM Metallopeptidases promotes neurite outgrowth in DRG neurons

(2017) Ricardo L. Sanz et al.   Scientific Reports

The immunomodulatory oligodendrocyte

(2016) Thomas Zeis et al.   BRAIN RESEARCH

On the Dependency of Cellular Protein Levels on mRNA Abundance

(2016) Yansheng Liu et al.   CELL

Native Piezo2 Interactomics Identifies Pericentrin as a Novel Regulator of Piezo2 in Somatosensory Neurons

(2016) Pratibha Narayanan et al.   JOURNAL OF PROTEOME RESEARCH

Does age matter? The impact of rodent age on study outcomes

(2016) Samuel J Jackson et al.   LABORATORY ANIMALS

Proteome Profiling Outperforms Transcriptome Profiling for Coexpression Based Gene Function Prediction

(2016) Jing Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Standardized Profiling of The Membrane-Enriched Proteome of Mouse Dorsal Root Ganglia (DRG) Provides Novel Insights Into Chronic Pain

(2016) Tom Rouwette et al.   MOLECULAR & CELLULAR PROTEOMICS

Mass-spectrometric exploration of proteome structure and function

(2016) Ruedi Aebersold et al.   NATURE

Bias in the reporting of sex and age in biomedical research on mouse models

(2016) Oscar Flórez-Vargas et al.   eLife

GABA Blocks Pathological but Not Acute TRPV1 Pain Signals

(2015) Christina Hanack et al.   CELL

Processing strategies and software solutions for data-independent acquisition in mass spectrometry

(2015) Aivett Bilbao et al.   PROTEOMICS

Complement System Part II: Role in Immunity

(2015) Nicolas S. Merle et al.   Frontiers in Immunology

Ion Mobility Tandem Mass Spectrometry Enhances Performance of Bottom-up Proteomics

(2014) Dominic Helm et al.   MOLECULAR & CELLULAR PROTEOMICS

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch

(2014) Kate Poole et al.   Nature Communications

Mutations in LAMB1 Cause Cobblestone Brain Malformation without Muscular or Ocular Abnormalities

(2013) Farid Radmanesh et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic Variants Associated With Development of TMD and Its Intermediate Phenotypes: The Genetic Architecture of TMD in the OPPERA Prospective Cohort Study

(2013) Shad B. Smith et al.   JOURNAL OF PAIN

Polymorphisms in the glucocorticoid receptor co-chaperone FKBP5 predict persistent musculoskeletal pain after traumatic stress exposure

(2013) Andrey V. Bortsov et al.   PAIN

Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development

(2013) R. B. Hamanaka et al.   Science Signaling

Cellular composition characterizing postnatal development and maturation of the mouse brain and spinal cord

(2012) YuHong Fu et al.   Brain Structure & Function

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Options and considerations when selecting a quantitative proteomics strategy

(2010) Bruno Domon et al.   NATURE BIOTECHNOLOGY

Genetic variation in the hypothalamic-pituitary-adrenal stress axis influences susceptibility to musculoskeletal pain: results from the EPIFUND study

(2009) K. L. Holliday et al.   ANNALS OF THE RHEUMATIC DISEASES

Dorsal root ganglia sensory neuronal cultures: a tool for drug discovery for peripheral neuropathies

(2009) Giorgia Melli et al.   Expert Opinion on Drug Discovery

Correlation of mRNA and protein in complex biological samples

(2009) Tobias Maier et al.   FEBS LETTERS

Sciatica

(2009) Carolyn J. Hildreth   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION