Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans
出版年份 2016 全文链接
标题
Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans
作者
关键词
-
出版物
JOURNAL OF PHYSIOLOGY-LONDON
Volume 594, Issue 24, Pages 7399-7417
出版商
Wiley
发表日期
2016-09-22
DOI
10.1113/jp272857
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Effects of testosterone on lean mass gain in elderly men: systematic review with meta-analysis of controlled and randomized studies
- (2015) Walter Krause Neto et al. AGE
- Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise
- (2015) Syed S. I. Bukhari et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Ribosome biogenesis adaptation in resistance training-induced human skeletal muscle hypertrophy
- (2015) Vandre C. Figueiredo et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling
- (2015) Matthew S. Brook et al. FASEB JOURNAL
- Regulation of rDNA transcription in response to growth factors, nutrients and energy
- (2015) Eric P. Kusnadi et al. GENE
- Blunted hypertrophic response in aged skeletal muscle is associated with decreased ribosome biogenesis
- (2015) Tyler J. Kirby et al. JOURNAL OF APPLIED PHYSIOLOGY
- The effects of age and resistance loading on skeletal muscle ribosome biogenesis
- (2015) Michael J. Stec et al. JOURNAL OF APPLIED PHYSIOLOGY
- Commentaries on Viewpoint: What is the relationship between acute measure of muscle protein synthesis and changes in muscle mass?
- (2015) JOURNAL OF APPLIED PHYSIOLOGY
- Acute resistance exercise activates rapamycin-sensitive and -insensitive mechanisms that control translational activity and capacity in skeletal muscle
- (2015) Daniel W. D. West et al. JOURNAL OF PHYSIOLOGY-LONDON
- Protein supplementation does not alter intramuscular anabolic signaling or endocrine response after resistance exercise in trained men
- (2015) Adam M. Gonzalez et al. NUTRITION RESEARCH
- Muscle Quality in Aging: a Multi-Dimensional Approach to Muscle Functioning with Applications for Treatment
- (2015) Maren S. Fragala et al. SPORTS MEDICINE
- Myostatin as a mediator of sarcopenia versus homeostatic regulator of muscle mass: insights using a new mass spectrometry-based assay
- (2015) H. Robert Bergen et al. Skeletal Muscle
- Aging Is Accompanied by a Blunted Muscle Protein Synthetic Response to Protein Ingestion
- (2015) Benjamin Toby Wall et al. PLoS One
- Architectural, functional and molecular responses to concentric and eccentric loading in human skeletal muscle
- (2014) M. V. Franchi et al. Acta Physiologica
- A validation of the application of D2O stable isotope tracer techniques for monitoring day-to-day changes in muscle protein subfraction synthesis in humans
- (2014) Daniel J. Wilkinson et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Muscle quality index improves with resistance exercise training in older adults
- (2014) Maren S. Fragala et al. EXPERIMENTAL GERONTOLOGY
- Resistance exercise training modulates acute gene expression during human skeletal muscle hypertrophy
- (2014) G. A. Nader et al. JOURNAL OF APPLIED PHYSIOLOGY
- Protein Ingestion to Stimulate Myofibrillar Protein Synthesis Requires Greater Relative Protein Intakes in Healthy Older Versus Younger Men
- (2014) D. R. Moore et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Acute Post-Exercise Myofibrillar Protein Synthesis Is Not Correlated with Resistance Training-Induced Muscle Hypertrophy in Young Men
- (2014) Cameron J. Mitchell et al. PLoS One
- Ageing has no effect on the regulation of the ubiquitin proteasome-related genes and proteins following resistance exercise
- (2014) Renae J. Stefanetti et al. Frontiers in Physiology
- Focal adhesion kinase is required for IGF-I-mediated growth of skeletal muscle cells via a TSC2/mTOR/S6K1-associated pathway
- (2013) Hannah Crossland et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- mTOR signaling response to resistance exercise is altered by chronic resistance training and detraining in skeletal muscle
- (2013) Riki Ogasawara et al. JOURNAL OF APPLIED PHYSIOLOGY
- Transient transcriptional events in human skeletal muscle at the outset of concentric resistance exercise training
- (2013) A. J. Murton et al. JOURNAL OF APPLIED PHYSIOLOGY
- Effects of Testosterone and Progressive Resistance Exercise in Healthy, Highly Functioning Older Men With Low-Normal Testosterone Levels
- (2013) Kerry L. Hildreth et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Two Weeks of Reduced Activity Decreases Leg Lean Mass and Induces “Anabolic Resistance” of Myofibrillar Protein Synthesis in Healthy Elderly
- (2013) Leigh Breen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Mechanical Muscle Function and Lean Body Mass During Supervised Strength Training and Testosterone Therapy in Aging Men with Low-Normal Testosterone Levels
- (2013) Thue Kvorning et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Assessing the "Physical Cliff": Detailed Quantification of Age-Related Differences in Daily Patterns of Physical Activity
- (2013) J. A. Schrack et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Muscle architecture and strength: Adaptations to short-term resistance training in older adults
- (2013) Tyler C. Scanlon et al. MUSCLE & NERVE
- Resistance training induced increase in muscle fiber size in young and older men
- (2012) A. A. Mero et al. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
- Undernutrition in older adults
- (2012) J. E. Morley FAMILY PRACTICE
- Muscle protein synthesis in response to nutrition and exercise
- (2012) P. J. Atherton et al. JOURNAL OF PHYSIOLOGY-LONDON
- Muscle Protein Synthetic Responses to Exercise: Effects of Age, Volume, and Intensity
- (2012) V. Kumar et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Skeletal Muscle Autophagy and Protein Breakdown Following Resistance Exercise are Similar in Younger and Older Adults
- (2012) C. S. Fry et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Sarcopenia, Dynapenia, and the Impact of Advancing Age on Human Skeletal Muscle Size and Strength; a Quantitative Review
- (2012) W. Kyle Mitchell et al. Frontiers in Physiology
- Aging with multimorbidity: A systematic review of the literature
- (2011) Alessandra Marengoni et al. AGEING RESEARCH REVIEWS
- Omega-3 polyunsaturated fatty acids augment the muscle protein anabolic response to hyperinsulinaemia–hyperaminoacidaemia in healthy young and middle-aged men and women
- (2011) Gordon I. Smith et al. CLINICAL SCIENCE
- Blunting of adaptive responses to resistance exercise training in women over 75y
- (2011) C.A. Greig et al. EXPERIMENTAL GERONTOLOGY
- Long-term synthesis rates of skeletal muscle DNA and protein are higher during aerobic training in older humans than in sedentary young subjects but are not altered by protein supplementation
- (2011) Matthew M. Robinson et al. FASEB JOURNAL
- Resistance exercise training improves age-related declines in leg vascular conductance and rejuvenates acute leg blood flow responses to feeding and exercise
- (2011) Bethan Phillips et al. JOURNAL OF APPLIED PHYSIOLOGY
- Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis
- (2011) Christopher S Fry et al. Skeletal Muscle
- Resistance exercise for muscular strength in older adults: A meta-analysis
- (2010) Mark D. Peterson et al. AGEING RESEARCH REVIEWS
- Muscle full effect after oral protein: time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signaling
- (2010) Philip J Atherton et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- A 2-wk reduction of ambulatory activity attenuates peripheral insulin sensitivity
- (2010) Rikke Krogh-Madsen et al. JOURNAL OF APPLIED PHYSIOLOGY
- Coomassie Staining as Loading Control in Western Blot Analysis
- (2010) Charlotte Welinder et al. JOURNAL OF PROTEOME RESEARCH
- Influence of Resistance Exercise on Lean Body Mass in Aging Adults
- (2010) MARK D. PETERSON et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Frailty and health related quality of life in older Mexican Americans
- (2009) Meredith C Masel et al. Health and Quality of Life Outcomes
- Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans
- (2009) David L. Mayhew et al. JOURNAL OF APPLIED PHYSIOLOGY
- Human muscle protein synthesis and breakdown during and after exercise
- (2009) Vinod Kumar et al. JOURNAL OF APPLIED PHYSIOLOGY
- Testosterone and Growth Hormone Improve Body Composition and Muscle Performance in Older Men
- (2009) Fred R. Sattler et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Cyclic stretch reduces myofibrillar protein synthesis despite increases in FAK and anabolic signalling in L6 cells
- (2009) P. J. Atherton et al. JOURNAL OF PHYSIOLOGY-LONDON
- Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis
- (2009) Micah J. Drummond et al. JOURNAL OF PHYSIOLOGY-LONDON
- Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exercise
- (2009) Daniel R. Moore et al. JOURNAL OF PHYSIOLOGY-LONDON
- Ageing populations: the challenges ahead
- (2009) Kaare Christensen et al. LANCET
- Physical Activity in the United States Measured by Accelerometer
- (2009) RICHARD P. TROIANO et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Protein supplementation before and after exercise does not further augment skeletal muscle hypertrophy after resistance training in elderly men
- (2008) Lex B Verdijk et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Metabolic Responses to Reduced Daily Steps in Healthy Nonexercising Men
- (2008) JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men
- (2008) Vinod Kumar et al. JOURNAL OF PHYSIOLOGY-LONDON
- Analyzing real-time PCR data by the comparative CT method
- (2008) Thomas D Schmittgen et al. Nature Protocols
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started