SMARCC2 mediates the regulation of DKK1 by the transcription factor EGR1 through chromatin remodeling to reduce the proliferative capacity of glioblastoma

Diffuse Glioma Heterogeneity and Its Therapeutic Implications

(2021) James G. Nicholson et al.   Cancer Discovery

The histone reader PHF7 cooperates with the SWI/SNF complex at cardiac super enhancers to promote direct reprogramming

(2021) Glynnis A. Garry et al.   NATURE CELL BIOLOGY

ProteoVision: web server for advanced visualization of ribosomal proteins

(2021) Petar I Penev et al.   NUCLEIC ACIDS RESEARCH

Targeting ARID1A Mutations in Cancer

(2021) Jaren Mullen et al.   CANCER TREATMENT REVIEWS

Plasmalemma vesicle-associated protein promotes angiogenesis in cholangiocarcinoma via the DKK1/CKAP4/PI3K signaling pathway

(2021) Yi Wang et al.   ONCOGENE

First report of Klebsiella aerogenes Inciting Stem Rot of Pearl Millet in Haryana, India

(2021) Vinod Kumar Malik et al.   PLANT DISEASE

SWI/SNF complex alterations as a biomarker of immunotherapy efficacy in pancreatic cancer

(2021) Gregory P. Botta et al.   JCI Insight

FGFR-inhibitor-mediated dismissal of SWI/SNF complexes from YAP-dependent enhancers induces adaptive therapeutic resistance

(2021) Yihao Li et al.   NATURE CELL BIOLOGY

Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung

(2021) Carla P. Concepcion et al.   Cancer Discovery

Limitations of functional neuroimaging for patient selection and surgical planning in glioma surgery

(2020) Tej D. Azad et al.   Neurosurgical Focus

Cryo-EM structure of SWI/SNF complex bound to a nucleosome

(2020) Yan Han et al.   NATURE

Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome

(2020) Felix R. Wagner et al.   NATURE

A pan-cancer analysis of PBAF complex mutations and their association with immunotherapy response

(2020) A. Ari Hakimi et al.   Nature Communications

A heterotrimeric SMARCB1–SMARCC2 subcomplex is required for the assembly and tumor suppression function of the BAF chromatin-remodeling complex

(2020) Guidong Chen et al.   Cell Discovery

SWI/SNF complex mutations promote thyroid tumor progression and insensitivity to redifferentiation therapies.

(2020) Mahesh Saqcena et al.   Cancer Discovery

The BAF complex in development and disease

(2019) Amelie Alfert et al.   Epigenetics & Chromatin

SWI/SNF chromatin remodeling controls Notch‐responsive enhancer accessibility

(2019) Zoe Pillidge et al.   EMBO REPORTS

HERC3-mediated SMAD7 ubiquitination degradation promotes autophagy-induced EMT and chemoresistance in glioblastoma

(2019) Hong Li et al.   CLINICAL CANCER RESEARCH

BRD9 defines a SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors

(2019) Xiaofeng Wang et al.   Nature Communications

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

(2019) William Farnaby et al.   Nature Chemical Biology

Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers

(2019) Sandra Schick et al.   NATURE GENETICS

Dynamic palmitoylation controls the microdomain localization of the DKK1 receptors CKAP4 and LRP6

(2019) Ryota Sada et al.   Science Signaling

The functional landscape of the human phosphoproteome

(2019) David Ochoa et al.   NATURE BIOTECHNOLOGY

Expanding the Spectrum of BAF-Related Disorders: De Novo Variants in SMARCC2 Cause a Syndrome with Intellectual Disability and Developmental Delay

(2018) Keren Machol et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Chromatin remodeling ATPase BRG1 and PTEN are synthetic lethal in prostate cancer

(2018) Yufeng Ding et al.   JOURNAL OF CLINICAL INVESTIGATION

Evolution and expression of core SWI/SNF genes in red algae

(2018) John W. Stiller et al.   JOURNAL OF PHYCOLOGY

Differential effects on lung and bone metastasis of breast cancer by Wnt signalling inhibitor DKK1

(2017) Xueqian Zhuang et al.   NATURE CELL BIOLOGY

SWI/SNF complex in cancer

(2017) Chao Lu et al.   NATURE GENETICS

Dickkopf1 destabilizes atherosclerotic plaques and promotes plaque formation by inducing apoptosis of endothelial cells through activation of ER stress

(2017) Mingxue Di et al.   Cell Death & Disease

BRG1-SWI/SNF-dependent regulation of the Wt1 transcriptional landscape mediates epicardial activity during heart development and disease

(2017) Joaquim Miguel Vieira et al.   Nature Communications

The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers

(2017) Burak H. Alver et al.   Nature Communications

CRISPRs for Optimal Targeting: Delivery of CRISPR Components as DNA, RNA, and Protein into Cultured Cells and Single-Cell Embryos

(2016) Evguenia Kouranova et al.   HUMAN GENE THERAPY

SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation

(2016) Xiaofeng Wang et al.   NATURE GENETICS

Glioblastoma: pathology, molecular mechanisms and markers

(2015) Kenneth Aldape et al.   ACTA NEUROPATHOLOGICA

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

(2015) Jing Lu et al.   CHEMISTRY & BIOLOGY

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development

(2015) Ramanathan Narayanan et al.   Cell Reports

ARID1A Mutations and PI3K/AKT Pathway Alterations in Endometriosis and Endometriosis-Associated Ovarian Carcinomas

(2013) Eleftherios Samartzis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DKK1 promotes hepatocellular carcinoma cell migration and invasion through β-catenin/MMP7 signaling pathway

(2013) Liang Chen et al.   Molecular Cancer

Failure to downregulate the BAF53a subunit of the SWI/SNF chromatin remodeling complex contributes to the differentiation block in rhabdomyosarcoma

(2013) R Taulli et al.   ONCOGENE

Combined analysis of exome sequencing points toward a major role for transcription regulation during brain development in autism

(2012) E Ben-David et al.   MOLECULAR PSYCHIATRY

ARID1A, a Factor That Promotes Formation of SWI/SNF-Mediated Chromatin Remodeling, Is a Tumor Suppressor in Gynecologic Cancers

(2011) B. Guan et al.   CANCER RESEARCH

SAGA and ATAC Histone Acetyl Transferase Complexes Regulate Distinct Sets of Genes and ATAC Defines a Class of p300-Independent Enhancers

(2011) Arnaud R. Krebs et al.   MOLECULAR CELL

PIK3CA mutations and loss of ARID1A protein expression are early events in the development of cystic ovarian clear cell adenocarcinoma

(2011) Sohei Yamamoto et al.   VIRCHOWS ARCHIV