The Persistence of HIV Diversity, Transcription, and Nef Protein in Kaposi’s Sarcoma Tumors during Antiretroviral Therapy

Reduced and highly diverse peripheral HIV-1 reservoir in virally suppressed patients infected with non-B HIV-1 strains in Uganda

(2022) Samira Joussef-Piña et al.   Retrovirology

Antiretroviral Therapy for HIV-Associated Cutaneous Kaposi’s Sarcoma: Clinical, HIV-related, and Sociodemographic Predictors of Outcome

(2021) Owen Ngalamika et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Cell-Associated HIV-1 Unspliced-to-Multiply-Spliced RNA Ratio at 12 Weeks of ART Predicts Immune Reconstitution on Therapy

(2021) Mirte Scherpenisse et al.   mBio

The Splice of Life: Does RNA Processing Have a Role in HIV-1 Persistence?

(2021) Alexander O. Pasternak et al.   Viruses-Basel

The Clonal Expansion Dynamics of the HIV-1 Reservoir: Mechanisms of Integration Site-Dependent Proliferation and HIV-1 Persistence

(2021) Yang-Hui Jimmy Yeh et al.   Viruses-Basel

Abundance of Nef and p-Tau217 in Brains of Individuals Diagnosed with HIV-Associated Neurocognitive Disorders Correlate with Disease Severance

(2021) Tatiana Pushkarsky et al.   MOLECULAR NEUROBIOLOGY

Why the HIV Reservoir Never Runs Dry: Clonal Expansion and the Characteristics of HIV-Infected Cells Challenge Strategies to Cure and Control HIV Infection

(2021) Chuen-Yen Lau et al.   Viruses-Basel

Real-world use of chemotherapy for Kaposi’s sarcoma in a large community-based HIV primary care system in Kenya

(2020) Esther E. Freeman et al.   BMC CANCER

HIV persists throughout deep tissues with repopulation from multiple anatomical sources

(2020) Antoine Chaillon et al.   JOURNAL OF CLINICAL INVESTIGATION

Treatment of advanced AIDS-associated Kaposi sarcoma in resource-limited settings: a three-arm, open-label, randomised, non-inferiority trial

(2020) Susan E Krown et al.   LANCET

IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era

(2020) Bui Quang Minh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Early progression and immune reconstitution inflammatory syndrome during treatment of mild-to-moderate Kaposi sarcoma in sub-Saharan Africa and South America

(2020) Mulinda Nyirenda et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Stage related PD‐L1 expression in Kaposi sarcoma tumor microenvironment

(2020) Beatrice Joest et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Lack of CD8+ T-cell co-localization with Kaposi’s sarcoma-associated herpesvirus infected cells in Kaposi’s sarcoma tumors

(2020) Salum J. Lidenge et al.   Oncotarget

Mechanistic differences underlying HIV latency in the gut and blood contribute to differential responses to latency-reversing agents

(2020) Sushama Telwatte et al.   AIDS

Concanamycin A counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes

(2020) Mark M. Painter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of a Versatile, Near Full Genome Amplification and Sequencing Approach for a Broad Variety of HIV-1 Group M Variants

(2019) Andrew N. Banin et al.   Viruses-Basel

HIV-Nef Protein Transfer to Endothelial Cells Requires Rac1 Activation and Leads to Endothelial Dysfunction: Implications for Statin Treatment in HIV Patients

(2019) Sarvesh Chelvanambi et al.   CIRCULATION RESEARCH

Lovastatin Inhibits HIV-1-Induced MHC-I Downregulation by Targeting Nef–AP-1 Complex Formation: A New Strategy to Boost Immune Eradication of HIV-1 Infected Cells

(2019) Bingfeng Liu et al.   Frontiers in Immunology

HIV-1 Tat Interacts with a Kaposi's Sarcoma-Associated Herpesvirus Reactivation-Upregulated Antiangiogenic Long Noncoding RNA, LINC00313, and Antagonizes Its Function

(2019) Wan-Shan Yang et al.   JOURNAL OF VIROLOGY

Tight-Binding Hydroxypyrazole HIV-1 Nef Inhibitors Suppress Viral Replication in Donor Mononuclear Cells and Reverse Nef-Mediated MHC-I Downregulation

(2019) Haibin Shi et al.   ACS Infectious Diseases

Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA

(2018) Jana Ferdin et al.   PLoS One

HIV-1 Envelope Protein gp120 Promotes Proliferation and the Activation of Glycolysis in Glioma Cell

(2018) Gabriel Valentín-Guillama et al.   Cancers

HIV-Nef Protein Persists in the Lungs of Aviremic HIV Patients and Induces Endothelial Cell Death

(2018) Sarvesh Chelvanambi et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA

(2018) Lechuang Chen et al.   Nature Communications

Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency

(2018) Sushama Telwatte et al.   PLoS Pathogens

Analysis of Competing HIV-1 Splice Donor Sites Uncovers a Tight Cluster of Splicing Regulatory Elements within Exon 2/2b

(2017) Anna-Lena Brillen et al.   JOURNAL OF VIROLOGY

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

(2017) Francis Mwimanzi et al.   JOURNAL OF VIROLOGY

Characterizing HIV-1 Splicing by Using Next-Generation Sequencing

(2017) Ann Emery et al.   JOURNAL OF VIROLOGY

HIV-1 matrix protein p17 and its variants promote human triple negative breast cancer cell aggressiveness

(2017) Francesca Caccuri et al.   Infectious Agents and Cancer

Accuracy of Clinical Suspicion and Pathologic Diagnosis of Kaposi Sarcoma in East Africa

(2016) Erin Amerson et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapy

(2016) Dirk P. Dittmer et al.   JOURNAL OF CLINICAL INVESTIGATION

HIV Maintains an Evolving and Dispersed Population in Multiple Tissues during Suppressive Combined Antiretroviral Therapy in Individuals with Cancer

(2016) Rebecca Rose et al.   JOURNAL OF VIROLOGY

Clonally expanded CD4+T cells can produce infectious HIV-1 in vivo

(2016) Francesco R. Simonetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality

(2016) Sarah B. Laskey et al.   PLoS Pathogens

HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling

(2016) Brennan S. Dirk et al.   Scientific Reports

Intracellular Nef Detected in Peripheral Blood Mononuclear Cells from HIV Patients

(2015) Ting Wang et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Cell-Associated HIV-1 DNA and RNA Decay Dynamics During Early Combination Antiretroviral Therapy in HIV-1-Infected Infants

(2015) Priyanka Uprety et al.   CLINICAL INFECTIOUS DISEASES

The Kynurenine Pathway of Tryptophan Catabolism and AIDS-Associated Kaposi Sarcoma in Africa

(2015) Helen Byakwaga et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Nef exosomes isolated from the plasma of individuals with HIV-associated dementia (HAD) can induce Aβ1–42 secretion in SH-SY5Y neural cells

(2015) Mahfuz B. Khan et al.   JOURNAL OF NEUROVIROLOGY

Task Shifting and Skin Punch for the Histologic Diagnosis of Kaposi's Sarcoma in Sub-Saharan Africa: A Public Health Solution to a Public Health Problem

(2015) Miriam O. Laker-Oketta et al.   ONCOLOGY

Exosomes Are Unlikely Involved in Intercellular Nef Transfer

(2015) Xiaoyu Luo et al.   PLoS One

COMET: adaptive context-based modeling for ultrafast HIV-1 subtype identification

(2014) Daniel Struck et al.   NUCLEIC ACIDS RESEARCH

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Synergy between Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 and HIV-1 Nef protein in promotion of angiogenesis and oncogenesis: role of the AKT signaling pathway

(2013) X Zhu et al.   ONCOGENE

HIV-1 Tat Promotes Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) vIL-6-Induced Angiogenesis and Tumorigenesis by Regulating PI3K/PTEN/AKT/GSK-3β Signaling Pathway

(2013) Feng Zhou et al.   PLoS One

24 Hours in the Life of HIV-1 in a T Cell Line

(2013) Pejman Mohammadi et al.   PLoS Pathogens

Primer3—new capabilities and interfaces

(2012) Andreas Untergasser et al.   NUCLEIC ACIDS RESEARCH

Dynamic regulation of HIV-1 mRNA populations analyzed by single-molecule enrichment and long-read sequencing

(2012) Karen E. Ocwieja et al.   NUCLEIC ACIDS RESEARCH

HIV Type 1 Nef Is Released from Infected Cells in CD45+ Microvesicles and Is Present in the Plasma of HIV-Infected Individuals

(2010) A.D. Raymond et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Kaposi Sarcoma–Associated Herpesvirus (KSHV) Seroprevalence in Population‐Based Samples of African Children: Evidence for At Least 2 Patterns of KSHV Transmission

(2009) Lisa M. Butler et al.   JOURNAL OF INFECTIOUS DISEASES

The role of macrophages in the development and progression of AIDS-related non-Hodgkin lymphoma

(2009) Leanne C. Huysentruyt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Extensive HIV-1 Intra-Host Recombination Is Common in Tissues with Abnormal Histopathology

(2009) Susanna L. Lamers et al.   PLoS One

Distinct Patterns of HIV-1 Evolution within Metastatic Tissues in Patients with Non-Hodgkins Lymphoma

(2009) Marco Salemi et al.   PLoS One

HIV Nef is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells

(2009) Metka Lenassi et al.   TRAFFIC