MYC multimers shield stalled replication forks from RNA polymerase

Heat shock induces premature transcript termination and reconfigures the human transcriptome

(2022) Simona Cugusi et al.   MOLECULAR CELL

Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters

(2021) Theresa Endres et al.   MOLECULAR CELL

MYC- and MIZ1-Dependent Vesicular Transport of Double-Strand RNA Controls Immune Evasion in Pancreatic Ductal Adenocarcinoma

(2021) Bastian Krenz et al.   CANCER RESEARCH

The MYC oncogene — the grand orchestrator of cancer growth and immune evasion

(2021) Renumathy Dhanasekaran et al.   Nature Reviews Clinical Oncology

MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts

(2021) Dimitrios Papadopoulos et al.   MOLECULAR CELL

MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”

(2021) Subhendu K. Das et al.   MOLECULAR CELL

Multiplexed single-cell proteomics using SCoPE2

(2021) Aleksandra A. Petelski et al.   Nature Protocols

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

(2021) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

UBR5 is co-amplified with MYC in breast tumors and encodes an ubiquitin ligase that limits MYC-dependent apoptosis

(2020) Xi Qiao et al.   CANCER RESEARCH

The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication

(2020) Madalena Tarsounas et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Target gene-independent functions of MYC oncoproteins

(2020) Apoorva Baluapuri et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples

(2020) Jiaming Li et al.   NATURE METHODS

Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase

(2019) Steffi Herold et al.   NATURE

MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation

(2019) Apoorva Baluapuri et al.   MOLECULAR CELL

The ENCODE Blacklist: Identification of Problematic Regions of the Genome

(2019) Haley M. Amemiya et al.   Scientific Reports

Improved CUT&RUN chromatin profiling tools

(2019) Michael P Meers et al.   eLife

Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function

(2018) Jan B Heidelberger et al.   EMBO REPORTS

EasyFRAP-web: a web-based tool for the analysis of fluorescence recovery after photobleaching data

(2018) Grigorios Koulouras et al.   NUCLEIC ACIDS RESEARCH

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

(2018) Ann Boija et al.   CELL

The OTUD5–UBR5 complex regulates FACT-mediated transcription at damaged chromatin

(2018) Angelo de Vivo et al.   NUCLEIC ACIDS RESEARCH

UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy

(2017) Tom Smith et al.   GENOME RESEARCH

Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling

(2017) Martin A. Michel et al.   MOLECULAR CELL

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor

(2017) Xingyue He et al.   Nature Chemical Biology

The essential kinase ATR: ensuring faithful duplication of a challenging genome

(2017) Joshua C. Saldivar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks

(2017) Winston X. Yan et al.   Nature Communications

Conflict Resolution in the Genome: How Transcription and Replication Make It Work

(2016) Stephan Hamperl et al.   CELL

HUWE1 interacts with PCNA to alleviate replication stress

(2016) Katherine N Choe et al.   EMBO REPORTS

Different promoter affinities account for specificity in MYC-dependent gene regulation

(2016) Francesca Lorenzin et al.   eLife

A Reversible and Highly Selective Inhibitor of the Proteasomal Ubiquitin Receptor Rpn13 Is Toxic to Multiple Myeloma Cells

(2015) Darci J. Trader et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC

(2015) Lance R. Thomas et al.   MOLECULAR CELL

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc

(2015) Xiao-Xin Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma

(2015) Daniel R. Carter et al.   Science Translational Medicine

The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer

(2014) Markus E. Diefenbacher et al.   JOURNAL OF CLINICAL INVESTIGATION

FANCD2-Controlled Chromatin Access of the Fanconi-Associated Nuclease FAN1 Is Crucial for the Recovery of Stalled Replication Forks

(2014) I. Chaudhury et al.   MOLECULAR AND CELLULAR BIOLOGY

Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles

(2014) Susanne Walz et al.   NATURE

Directed evolution of APEX2 for electron microscopy and proximity labeling

(2014) Stephanie S Lam et al.   NATURE METHODS

Confinement and Deformation of Single Cells and Their Nuclei Inside Size-Adapted Microtubes

(2014) Britta Koch et al.   Advanced Healthcare Materials

Partition of Myc into Immobile vs. Mobile Complexes within Nuclei

(2013) Tilman Rosales et al.   Scientific Reports

c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells

(2012) Zuqin Nie et al.   CELL

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

(2012) Charles Y. Lin et al.   CELL

rapidSTORM: accurate, fast open-source software for localization microscopy

(2012) Steve Wolter et al.   NATURE METHODS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

(2010) Denis Drygin et al.   CANCER RESEARCH

The interaction between Myc and Miz1 is required to antagonize TGF -dependent autocrine signaling during lymphoma formation and maintenance

(2010) J. van Riggelen et al.   GENES & DEVELOPMENT

On the Use of Ripley's K-Function and Its Derivatives to Analyze Domain Size

(2009) Maria A. Kiskowski et al.   BIOPHYSICAL JOURNAL

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex

(2008) Aude Dupré et al.   Nature Chemical Biology