标题
MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
作者
关键词
Myc, Topoisomerase, Transcription, DNA topology, supercoiling, chromatin, polymerase, TOP1, TOP2, cancer
出版物
MOLECULAR CELL
Volume 82, Issue 1, Pages 140-158.e12
出版商
Elsevier BV
发表日期
2021-12-09
DOI
10.1016/j.molcel.2021.11.016
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting MYCN in Pediatric and Adult Cancers
- (2021) Zhihui Liu et al. Frontiers in Oncology
- Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing
- (2021) Andrés Herrero-Ruiz et al. Cell Reports
- Transcription-mediated supercoiling regulates genome folding and loop formation
- (2021) Maria Victoria Neguembor et al. MOLECULAR CELL
- Highly accurate protein structure prediction with AlphaFold
- (2021) John Jumper et al. NATURE
- Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
- (2021) Anika Wiegard et al. MOLECULAR CELL
- Target gene-independent functions of MYC oncoproteins
- (2020) Apoorva Baluapuri et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Suppressing proteasome mediated processing of Topoisomerase II DNA-protein complexes preserves genome integrity
- (2020) Nicholas Sciascia et al. eLife
- Transcription in Living Cells: Molecular Mechanisms of Bursting
- (2020) Joseph Rodriguez et al. Annual Review of Biochemistry
- Topoisomerase IIα is essential for maintenance of mitotic chromosome structure
- (2020) Christian F. Nielsen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dissecting transcriptional amplification by MYC
- (2020) Zuqin Nie et al. eLife
- Discovery and Mechanistic Study of Tailor-Made Quinoline Derivatives as Topoisomerase 1 Poisons with Potent Anticancer Activity
- (2019) Biswajit Kundu et al. JOURNAL OF MEDICINAL CHEMISTRY
- epic2 efficiently finds diffuse domains in ChIP-seq data
- (2019) Endre Bakken Stovner et al. BIOINFORMATICS
- Generation of conditional auxin-inducible degron (AID) cells and tight control of degron-fused proteins using the degradation inhibitor auxinole
- (2019) Aisha Yesbolatova et al. METHODS
- The ENCODE Blacklist: Identification of Problematic Regions of the Genome
- (2019) Haley M. Amemiya et al. Scientific Reports
- Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity
- (2019) Tung T. Le et al. CELL
- Multiple direct interactions of TBP with the MYC oncoprotein
- (2019) Yong Wei et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome
- (2019) William H. Gittens et al. Nature Communications
- Neutral Porphyrin Derivative Exerts Anticancer Activity by Targeting Cellular Topoisomerase I (Top1) and Promotes Apoptotic Cell Death without Stabilizing Top1-DNA Cleavage Complexes
- (2018) Subhendu K. Das et al. JOURNAL OF MEDICINAL CHEMISTRY
- SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis
- (2018) Matthias Muhar et al. SCIENCE
- Coactivator condensation at super-enhancers links phase separation and gene control
- (2018) Benjamin R. Sabari et al. SCIENCE
- The Expanding World of N-MYC–Driven Tumors
- (2018) David S. Rickman et al. Cancer Discovery
- Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain
- (2018) Claire Bedez et al. Scientific Reports
- MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis
- (2018) Manpreet Kalkat et al. MOLECULAR CELL
- Resveratrol: A novel type of topoisomerase II inhibitor
- (2017) Joyce H. Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PAF1 complex component Leo1 helps recruitDrosophilaMyc to promoters
- (2017) Jennifer M. Gerlach et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle
- (2017) Gabriele Büchel et al. Cell Reports
- Permanganate/S1 Nuclease Footprinting Reveals Non-B DNA Structures with Regulatory Potential across a Mammalian Genome
- (2017) Fedor Kouzine et al. Cell Systems
- MultiQC: summarize analysis results for multiple tools and samples in a single report
- (2016) Philip Ewels et al. BIOINFORMATICS
- RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription
- (2016) Laura Baranello et al. CELL
- Nucleoporin-mediated regulation of cell identity genes
- (2016) Arkaitz Ibarra et al. GENES & DEVELOPMENT
- Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells
- (2016) Subhendu K. Das et al. NUCLEIC ACIDS RESEARCH
- Rapid Protein Depletion in Human Cells by Auxin-Inducible Degron Tagging with Short Homology Donors
- (2016) Toyoaki Natsume et al. Cell Reports
- Different promoter affinities account for specificity in MYC-dependent gene regulation
- (2016) Francesca Lorenzin et al. eLife
- Emerging therapies in systemic lupus erythematous: from clinical trial to the real life
- (2016) Huza Zhang et al. Expert Review of Clinical Pharmacology
- ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization
- (2015) Guangchuang Yu et al. BIOINFORMATICS
- Ligand-Dependent Enhancer Activation Regulated by Topoisomerase-I Activity
- (2015) Janusz Puc et al. CELL
- Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes
- (2015) Ram Madabhushi et al. CELL
- Orchestrating high-throughput genomic analysis with Bioconductor
- (2015) Wolfgang Huber et al. NATURE METHODS
- Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability
- (2015) Stephanie A. Schalbetter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases
- (2014) Li Shen et al. BMC GENOMICS
- Mechanism of Transcriptional Bursting in Bacteria
- (2014) Shasha Chong et al. CELL
- deepTools: a flexible platform for exploring deep-sequencing data
- (2014) Fidel Ramírez et al. NUCLEIC ACIDS RESEARCH
- Topoisomerases facilitate transcription of long genes linked to autism
- (2013) Ian F. King et al. NATURE
- Transcription-generated torsional stress destabilizes nucleosomes
- (2013) Sheila S Teves et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Transcription-dependent dynamic supercoiling is a short-range genomic force
- (2013) Fedor Kouzine et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A rapid and sensitive assay for DNA–protein covalent complexes in living cells
- (2013) Kostantin Kiianitsa et al. NUCLEIC ACIDS RESEARCH
- Ensembl 2014
- (2013) Paul Flicek et al. NUCLEIC ACIDS RESEARCH
- Transcription Under Torsion
- (2013) J. Ma et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Gene regulation and priming by topoisomerase IIα in embryonic stem cells
- (2013) Sudhir Thakurela et al. Nature Communications
- Topoisomerase IIα promotes activation of RNA polymerase I transcription by facilitating pre-initiation complex formation
- (2013) Swagat Ray et al. Nature Communications
- Torque modulates nucleosome stability and facilitates H2A/H2B dimer loss
- (2013) Maxim Y. Sheinin et al. Nature Communications
- Drugging Topoisomerases: Lessons and Challenges
- (2012) Yves Pommier ACS Chemical Biology
- The importance of being supercoiled: How DNA mechanics regulate dynamic processes
- (2012) Laura Baranello et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
- (2012) Zuqin Nie et al. CELL
- Transcriptional Amplification in Tumor Cells with Elevated c-Myc
- (2012) Charles Y. Lin et al. CELL
- MYC on the Path to Cancer
- (2012) Chi V. Dang CELL
- R Loops: From Transcription Byproducts to Threats to Genome Stability
- (2012) Andrés Aguilera et al. MOLECULAR CELL
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Topoisomerase II is required for the production of long Pol II gene transcripts in yeast
- (2012) Ricky S. Joshi et al. NUCLEIC ACIDS RESEARCH
- Target genes of Topoisomerase II regulate neuronal survival and are defined by their chromatin state
- (2012) V. K. Tiwari et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Myc’s secret life without Max
- (2011) Peter Gallant et al. CELL CYCLE
- Chromosome length influences replication-induced topological stress
- (2011) Andreas Kegel et al. NATURE
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- c-Myc Regulates Transcriptional Pause Release
- (2010) Peter B. Rahl et al. CELL
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Rates of in situ transcription and splicing in large human genes
- (2009) Jarnail Singh et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Dynamic Regulation of Nucleosome Positioning in the Human Genome
- (2008) Dustin E. Schones et al. CELL
- The functional response of upstream DNA to dynamic supercoiling in vivo
- (2008) Fedor Kouzine et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
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