A rapid RIG-I signaling relay mediates efficient antiviral response

The molecular mechanism of RIG‐I activation and signaling*

(2021) Daniel Thoresen et al.   IMMUNOLOGICAL REVIEWS

Spatiotemporal dynamics of innate immune signaling via RIG-I–like receptors

(2020) Katharina Esser-Nobis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell type- and replication stage-specific influenza virus responses in vivo

(2020) Elizabeth J. Fay et al.   PLoS Pathogens

RIG-I Selectively Discriminates against 5′-Monophosphate RNA

(2019) Xiaoming Ren et al.   Cell Reports

MAVS polymers smaller than 80 nm induce mitochondrial membrane remodeling and interferon signaling

(2019) Ming‐Shih Hwang et al.   FEBS Journal

Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity

(2019) Cristhian Cadena et al.   CELL

Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub

(2018) Sarah Louise Latty et al.   eLife

A minimal RNA ligand for potent RIG-I activation in living mice

(2018) Melissa M. Linehan et al.   Science Advances

Therapeutically active RIG-I agonist induces immunogenic tumor cell killing in breast cancers

(2018) David L Elion et al.   CANCER RESEARCH

Regional Differences in Airway Epithelial Cells Reveal Tradeoff between Defense against Oxidative Stress and Defense against Rhinovirus

(2018) Valia T. Mihaylova et al.   Cell Reports

An ultraprocessive, accurate reverse transcriptase encoded by a metazoan group II intron

(2017) Chen Zhao et al.   RNA

Subcellular Localizations of RIG-I, TRIM25, and MAVS Complexes

(2016) M. T. Sánchez-Aparicio et al.   JOURNAL OF VIROLOGY

An RNA Molecule Derived From Sendai Virus DI Particles Induces Antitumor Immunity and Cancer Cell-selective Apoptosis

(2016) Li-Wen Liu et al.   MOLECULAR THERAPY

An autoinhibitory mechanism modulates MAVS activity in antiviral innate immune response

(2015) Yuheng Shi et al.   Nature Communications

Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I

(2014) Bin Wu et al.   MOLECULAR CELL

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates

(2014) Delphine Goubau et al.   NATURE

Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I

(2014) Alys Peisley et al.   NATURE

RIG-I Self-Oligomerization Is Either Dispensable or Very Transient for Signal Transduction

(2014) Jade Louber et al.   PLoS One

FindFoci: A Focus Detection Algorithm with Automated Parameter Training That Closely Matches Human Assignments, Reduces Human Inconsistencies and Increases Speed of Analysis

(2014) Alex D. Herbert et al.   PLoS One

Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions

(2014) Swantje Liedmann et al.   Nature Communications

Incoming RNA Virus Nucleocapsids Containing a 5′-Triphosphorylated Genome Activate RIG-I and Antiviral Signaling

(2013) Michaela Weber et al.   Cell Host & Microbe

Defining the functional determinants for RNA surveillance by RIG-I

(2013) Andrew Kohlway et al.   EMBO REPORTS

Cytosolic Sensing of Viruses

(2013) Delphine Goubau et al.   IMMUNITY

RIG-I Forms Signaling-Competent Filaments in an ATP-Dependent, Ubiquitin-Independent Manner

(2013) Alys Peisley et al.   MOLECULAR CELL

The Mitochondrial Targeting Chaperone 14-3-3ε Regulates a RIG-I Translocon that Mediates Membrane Association and Innate Antiviral Immunity

(2012) Helene Minyi Liu et al.   Cell Host & Microbe

A Sendai Virus-Derived RNA Agonist of RIG-I as a Virus Vaccine Adjuvant

(2012) L. Martínez-Gil et al.   JOURNAL OF VIROLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

(2012) Koji Onomoto et al.   PLoS One

Structural Basis for the Activation of Innate Immune Pattern-Recognition Receptor RIG-I by Viral RNA

(2011) Eva Kowalinski et al.   CELL

Structural Insights into RNA Recognition by RIG-I

(2011) Dahai Luo et al.   CELL

MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

(2011) Fajian Hou et al.   CELL

Molecular Mechanism of Signal Perception and Integration by the Innate Immune Sensor Retinoic Acid-inducible Gene-I (RIG-I)

(2011) Marco Binder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus

(2011) S. M. Horner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of the RIG-I Pathway Reveals a Signaling Role of Unanchored Polyubiquitin Chains in Innate Immunity

(2010) Wenwen Zeng et al.   CELL

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

(2010) A. Baum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY