标题
The burgeoning field of innate immune-mediated disease and autoinflammation
作者
关键词
-
出版物
JOURNAL OF PATHOLOGY
Volume 241, Issue 2, Pages 123-139
出版商
Wiley
发表日期
2016-09-29
DOI
10.1002/path.4812
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Canakinumab treatment for patients with active recurrent or chronic TNF receptor-associated periodic syndrome (TRAPS): an open-label, phase II study
- (2016) Marco Gattorno et al. ANNALS OF THE RHEUMATIC DISEASES
- Old Dogs, New Tricks: Monogenic Autoinflammatory Disease Unleashed
- (2016) Monique Stoffels et al. Annual Review of Genomics and Human Genetics
- Atorvastatin suppresses NLRP3 inflammasome activation via TLR4/MyD88/NF-κB signaling in PMA-stimulated THP-1 monocytes
- (2016) Fanqi Kong et al. BIOMEDICINE & PHARMACOTHERAPY
- A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR
- (2016) A Tosco et al. CELL DEATH AND DIFFERENTIATION
- The role of Resveratrol-induced mitophagy/autophagy in peritoneal mesothelial cells inflammatory injury via NLRP3 inflammasome activation triggered by mitochondrial ROS
- (2016) Jun Wu et al. EXPERIMENTAL CELL RESEARCH
- Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases
- (2016) Julie Jurczyluk et al. IMMUNOLOGY AND CELL BIOLOGY
- Regulation of inflammasomes by autophagy
- (2016) Tatsuya Saitoh et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Inflammasomes link vascular disease with neuroinflammation and brain disorders
- (2016) Nikolett Lénárt et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Ultrasound and magnetic resonance imaging assessment of joint disease in symptomatic patients with cystic fibrosis arthropathy
- (2016) G. Fitch et al. Journal of Cystic Fibrosis
- The RNA- and TRIM25-Binding Domains of Influenza Virus NS1 Protein Are Essential for Suppression of NLRP3 Inflammasome-Mediated Interleukin-1β Secretion
- (2016) Miyu Moriyama et al. JOURNAL OF VIROLOGY
- Cystic fibrosis
- (2016) J Stuart Elborn LANCET
- DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesis
- (2016) Petro Starokadomskyy et al. NATURE IMMUNOLOGY
- Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS
- (2016) Yong Hwan Park et al. NATURE IMMUNOLOGY
- Type I interferonopathies in pediatric rheumatology
- (2016) Stefano Volpi et al. Pediatric Rheumatology
- Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease
- (2016) Qing Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
- (2016) Seth L. Masters et al. Science Translational Medicine
- IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis
- (2016) Rossana G. Iannitti et al. Nature Communications
- Brief Report: Association of Tumor Necrosis Factor Receptor-Associated Periodic Syndrome With Gonosomal Mosaicism of a Novel 24-NucleotideTNFRSF1ADeletion
- (2016) Dorota M. Rowczenio et al. Arthritis & Rheumatology
- Brief Report: Severe Inflammation Following Vaccination AgainstStreptococcus pneumoniaein Patients With Cryopyrin-Associated Periodic Syndromes
- (2016) Ulrich A. Walker et al. Arthritis & Rheumatology
- X-Box–Binding Protein 1 and Innate Immune Responses of Human Cystic Fibrosis Alveolar Macrophages
- (2015) Bob A. Lubamba et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Recommendations for the management of autoinflammatory diseases
- (2015) Nienke M ter Haar et al. ANNALS OF THE RHEUMATIC DISEASES
- Molecular Mechanisms in Genetically Defined Autoinflammatory Diseases: Disorders of Amplified Danger Signaling
- (2015) Adriana Almeida de Jesus et al. Annual Review of Immunology
- Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?
- (2015) Justine M. Abais et al. ANTIOXIDANTS & REDOX SIGNALING
- Mitochondrial damage contributes toPseudomonas aeruginosaactivation of the inflammasome and is downregulated by autophagy
- (2015) Majid Sakhi Jabir et al. Autophagy
- Inhibition of autophagy induces IL-1β release from ARPE-19 cells via ROS mediated NLRP3 inflammasome activation under high glucose stress
- (2015) Huanqi Shi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Molecular mechanisms regulating NLRP3 inflammasome activation
- (2015) Eun-Kyeong Jo et al. Cellular & Molecular Immunology
- Type I interferonopathies: Mendelian type I interferon up-regulation
- (2015) Yanick J Crow CURRENT OPINION IN IMMUNOLOGY
- Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage
- (2015) Denise N. Bronner et al. IMMUNITY
- The cooperation between the autophagy machinery and the inflammasome to implement an appropriate innate immune response: do they regulate each other?
- (2015) Dalia H. A. Abdelaziz et al. IMMUNOLOGICAL REVIEWS
- IL-1 receptor antagonist reduces endotoxin-induced airway inflammation in healthy volunteers
- (2015) Michelle L. Hernandez et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The immunogenetics of Behçet's disease: A comprehensive review
- (2015) Masaki Takeuchi et al. JOURNAL OF AUTOIMMUNITY
- Human Disease Phenotypes Associated With Mutations in TREX1
- (2015) Gillian I. Rice et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production
- (2015) Anja Brehm et al. JOURNAL OF CLINICAL INVESTIGATION
- Knockdown of MVK does not lead to changes in NALP3 expression or activation
- (2015) Fulvio Celsi et al. Journal of Inflammation-London
- Persistent cystic fibrosis isolate Pseudomonas aeruginosa strain RP73 exhibits an under-acylated LPS structure responsible of its low inflammatory activity
- (2015) Flaviana Di Lorenzo et al. MOLECULAR IMMUNOLOGY
- Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease
- (2015) Qing Zhou et al. NATURE GENETICS
- Management of hereditary recurrent fevers—SHARE experience
- (2015) Guillaume Sarrabay et al. Nature Reviews Rheumatology
- Perception of self: distinguishing autoimmunity from autoinflammation
- (2015) Tessa S. van Kempen et al. Nature Reviews Rheumatology
- Acquired familial Mediterranean fever associated with a somatic MEFV mutation in a patient with JAK2 associated post-polycythemia myelofibrosis
- (2015) Yael Shinar et al. Orphanet Journal of Rare Diseases
- Protein misfolding and dysregulated protein homeostasis in autoinflammatory diseases and beyond
- (2015) Amma F. Agyemang et al. Seminars in Immunopathology
- New monogenic autoinflammatory diseases—a clinical overview
- (2015) Scott W. Canna et al. Seminars in Immunopathology
- Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation
- (2015) Ping-xia Zhang et al. Nature Communications
- Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis
- (2015) Alessandro Rimessi et al. Nature Communications
- NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases
- (2015) Amna Abderrazak et al. Redox Biology
- Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome
- (2014) Mi-Hyang Cho et al. Autophagy
- HMGB1–DNA complex-induced autophagy limits AIM2 inflammasome activation through RAGE
- (2014) Liying Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy
- (2014) K. Pohl et al. BLOOD
- Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway
- (2014) Zhao V. Wang et al. CELL
- Role of the Microbiota in Immunity and Inflammation
- (2014) Yasmine Belkaid et al. CELL
- Regulation of the Inflammasome by Ceramide in Cystic Fibrosis Lungs
- (2014) Heike Grassmé et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- TLR dependent XBP-1 activation induces an autocrine loop in rheumatoid arthritis synoviocytes
- (2014) Sinisa Savic et al. JOURNAL OF AUTOIMMUNITY
- Tumor necrosis factor receptor-associated periodic syndrome as a model linking autophagy and inflammation in protein aggregation diseases
- (2014) Tiziana Bachetti et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome
- (2014) Hao Xu et al. NATURE
- Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
- (2014) Edward T. Chouchani et al. NATURE
- Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
- (2014) Gillian I Rice et al. NATURE GENETICS
- An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome
- (2014) Scott W Canna et al. NATURE GENETICS
- New monogenic diseases span the immunological disease continuum
- (2014) Sinisa Savic et al. Nature Reviews Rheumatology
- Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2
- (2014) Qing Zhou et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mutant Adenosine Deaminase 2 in a Polyarteritis Nodosa Vasculopathy
- (2014) Paulina Navon Elkan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Activated STING in a Vascular and Pulmonary Syndrome
- (2014) Yin Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
- IFN-γ Stimulates Autophagy-Mediated Clearance of Burkholderia cenocepacia in Human Cystic Fibrosis Macrophages
- (2014) Kaivon Assani et al. PLoS One
- Neutrophil-Mediated Phagocytic Host Defense Defect in Myeloid Cftr-Inactivated Mice
- (2014) Hang Pong Ng et al. PLoS One
- Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4
- (2014) H. S. Kuehn et al. SCIENCE
- The immunological function of familial Mediterranean fever disease protein Pyrin
- (2014) JieLing Yang et al. Science China-Life Sciences
- Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics
- (2014) Glynn Dennis et al. ARTHRITIS RESEARCH & THERAPY
- Anti-Interleukin-1 Therapy in the Management of Gout
- (2014) Naomi Schlesinger Current Rheumatology Reports
- Brief Report: Involvement ofTNFRSF11AMolecular Defects in Autoinflammatory Disorders
- (2014) Isabelle Jéru et al. Arthritis & Rheumatology
- Rhinovirus-Induced Calcium Flux Triggers NLRP3 and NLRC5 Activation in Bronchial Cells
- (2013) Kathy Triantafilou et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Regulation Where Autophagy Intersects the Inflammasome
- (2013) Mary A. Rodgers et al. ANTIOXIDANTS & REDOX SIGNALING
- Burkholderia cenocepacia J2315 escapes to the cytosol and actively subverts autophagy in human macrophages
- (2013) Souhaila Al-Khodor et al. CELLULAR MICROBIOLOGY
- An Update on Autoinflammatory Diseases
- (2013) F. Ciccarelli et al. CURRENT MEDICINAL CHEMISTRY
- The human microbiome and autoimmunity
- (2013) Amy D. Proal et al. CURRENT OPINION IN RHEUMATOLOGY
- Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis
- (2013) Quan Qiu et al. EMBO JOURNAL
- Canakinumab in pediatric rheumatic diseases
- (2013) Nico M Wulffraat et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation
- (2013) Shankar S. Iyer et al. IMMUNITY
- Extracellular Acidosis Is a Novel Danger Signal Alerting Innate Immunity via the NLRP3 Inflammasome
- (2013) Kristiina Rajamäki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of membrane-trafficking small GTPases in the regulation of autophagy
- (2013) C. F. Bento et al. JOURNAL OF CELL SCIENCE
- The role of respiratory viruses in adult patients with cystic fibrosis receiving intravenous antibiotics for a pulmonary exacerbation
- (2013) C. Etherington et al. Journal of Cystic Fibrosis
- Treating inflammation by blocking interleukin-1 in humans
- (2013) Charles A. Dinarello et al. SEMINARS IN IMMUNOLOGY
- Incidence and clinical impact of respiratory viruses in adults with cystic fibrosis
- (2013) William G Flight et al. THORAX
- Autophagy contributes to inflammation in patients with TNFR-associated periodic syndrome (TRAPS)
- (2012) Tiziana Bachetti et al. ANNALS OF THE RHEUMATIC DISEASES
- Involvement of X-box binding protein 1 and reactive oxygen species pathways in the pathogenesis of tumour necrosis factor receptor-associated periodic syndrome
- (2012) Laura J Dickie et al. ANNALS OF THE RHEUMATIC DISEASES
- Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator
- (2012) Alessandro Luciani et al. Autophagy
- Autoinflammatory syndromes and cellular responses to stress: pathophysiology, diagnosis and new treatment perspectives
- (2012) Sinisa Savic et al. BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
- Blockade of XBP1 splicing by inhibition of IRE1 is a promising therapeutic option in multiple myeloma
- (2012) N. Mimura et al. BLOOD
- Atypical Activation of the Unfolded Protein Response in Cystic Fibrosis Airway Cells Contributes to p38 MAPK-Mediated Innate Immune Responses
- (2012) C. J. Blohmke et al. JOURNAL OF IMMUNOLOGY
- Proinflammatory Mediators Disrupt Glucose Homeostasis in Airway Surface Liquid
- (2012) J. P. Garnett et al. JOURNAL OF IMMUNOLOGY
- Activation of the Pyrin Inflammasome by Intracellular Burkholderia cenocepacia
- (2012) M. A. Gavrilin et al. JOURNAL OF IMMUNOLOGY
- Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
- (2012) Chong-Shan Shi et al. NATURE IMMUNOLOGY
- Cold Urticaria, Immunodeficiency, and Autoimmunity Related toPLCG2Deletions
- (2012) Michael J. Ombrello et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy of interleukin-1-targeting drugs in mevalonate kinase deficiency
- (2012) C. Galeotti et al. RHEUMATOLOGY
- Mutations in IL36RN/IL1F5 Are Associated with the Severe Episodic Inflammatory Skin Disease Known as Generalized Pustular Psoriasis
- (2011) Alexandros Onoufriadis et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Mutations in proteasome subunit β type 8 cause chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature with evidence of genetic and phenotypic heterogeneity
- (2011) Yin Liu et al. ARTHRITIS AND RHEUMATISM
- Autophagy stimulation by rapamycin suppresses lung inflammation and infection byBurkholderia cenocepaciain a model of cystic fibrosis
- (2011) Basant A. Abdulrahman et al. Autophagy
- Familial Mediterranean fever and related periodic fever syndromes/autoinflammatory diseases
- (2011) Sinisa Savic et al. CURRENT OPINION IN RHEUMATOLOGY
- Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice
- (2011) Xiao Su et al. INFLAMMATION RESEARCH
- Is caspase 1 central to activation of interleukin-1?
- (2011) Miriam Wittmann et al. JOINT BONE SPINE
- Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
- (2011) James Harris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
- (2011) Ariel C. Bulua et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Gout and hyperuricaemia in adults with cystic fibrosis
- (2011) Alex Horsley et al. JOURNAL OF THE ROYAL SOCIETY OF MEDICINE
- Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis
- (2011) Slaheddine Marrakchi et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Role of Uric Acid as an Endogenous Danger Signal in Immunity and Inflammation
- (2011) Faranak Ghaemi-Oskouie et al. Current Rheumatology Reports
- Cystic fibrosis: A disorder with defective autophagy
- (2010) Alessandro Luciani et al. Autophagy
- Ceramide in Pseudomonas aeruginosa Infections and Cystic Fibrosis
- (2010) Katrin Anne Becker et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
- (2010) Alessandro Luciani et al. NATURE CELL BIOLOGY
- TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
- (2010) Fabio Martinon et al. NATURE IMMUNOLOGY
- Aspergillus fumigatus Stimulates the NLRP3 Inflammasome through a Pathway Requiring ROS Production and the Syk Tyrosine Kinase
- (2010) Najwane Saïd-Sadier et al. PLoS One
- The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA
- (2009) Irving C. Allen et al. IMMUNITY
- Airway Epithelial Inflammation-induced Endoplasmic Reticulum Ca2+Store Expansion Is Mediated by X-box Binding Protein-1
- (2009) Mary E. B. Martino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response
- (2009) Gillian I Rice et al. NATURE GENETICS
- An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist
- (2009) Ivona Aksentijevich et al. NEW ENGLAND JOURNAL OF MEDICINE
- Use of Canakinumab in the Cryopyrin-Associated Periodic Syndrome
- (2009) Helen J. Lachmann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
- (2009) S. S. Iyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The pattern of response to anti–interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis
- (2008) Marco Gattorno et al. ARTHRITIS AND RHEUMATISM
- Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity
- (2008) Daniel B. Stetson et al. CELL
- Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways
- (2008) R. Tirouvanziam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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