Microglia depletion exacerbates retinal ganglion cell loss in a mouse model of glaucoma

Minocycline suppresses disease-associated microglia (DAM) in a model of photoreceptor cell degeneration

(2022) Ema Ozaki et al.   EXPERIMENTAL EYE RESEARCH

When Is a Control Not a Control? Reactive Microglia Occur Throughout the Control Contralateral Pathway of Retinal Ganglion Cell Projections in Experimental Glaucoma

(2021) James R. Tribble et al.   Translational Vision Science & Technology

Reactive astrocyte nomenclature, definitions, and future directions

(2021) Carole Escartin et al.   NATURE NEUROSCIENCE

The Interaction Between Microglia and Macroglia in Glaucoma

(2021) Xiaohuan Zhao et al.   Frontiers in Neuroscience

Neurotoxic reactive astrocytes induce cell death via saturated lipids

(2021) Kevin A. Guttenplan et al.   NATURE

Ocular hypertension suppresses homeostatic gene expression in optic nerve head microglia of DBA/2 J mice

(2020) James R. Tribble et al.   Molecular Brain

Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration

(2020) Sudeshna Das et al.   Journal of Neuroinflammation

Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury

(2020) Kevin A. Guttenplan et al.   Cell Reports

Crosstalk Between Astrocytes and Microglia: An Overview

(2020) Agata Matejuk et al.   Frontiers in Immunology

Minocycline reduces inflammatory response and cell death in a S100B retina degeneration model

(2020) Pia Grotegut et al.   Journal of Neuroinflammation

Mouse model of ocular hypertension with retinal ganglion cell degeneration

(2019) Ryo Mukai et al.   PLoS One

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

(2019) Elizabeth Spangenberg et al.   Nature Communications

Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma

(2018) Huihui Chen et al.   Nature Communications

Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries

(2017) Daniel Sun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Mice Homozygous for a Deletion in the Glaucoma Susceptibility Locus INK4 Show Increased Vulnerability of Retinal Ganglion Cells to Elevated Intraocular Pressure

(2016) Shan Gao et al.   AMERICAN JOURNAL OF PATHOLOGY

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke

(2016) Gergely Szalay et al.   Nature Communications

A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice

(2016) Yoko A. Ito et al.   Jove-Journal of Visualized Experiments

Astrocyte Structural and Molecular Response to Elevated Intraocular Pressure Occurs Rapidly and Precedes Axonal Tubulin Rearrangement within the Optic Nerve Head in a Rat Model

(2016) Shandiz Tehrani et al.   PLoS One

Neurodegeneration severity can be predicted from early microglia alterations monitored in vivo in a mouse model of chronic glaucoma

(2015) A. Bosco et al.   Disease Models & Mechanisms

Isolation of intact astrocytes from the optic nerve head of adult mice

(2015) Hee Joo Choi et al.   EXPERIMENTAL EYE RESEARCH

Ontogeny of CX3CR1-EGFP expressing cells unveil microglia as an integral component of the postnatal subventricular zone

(2015) Anna L. Xavier et al.   Frontiers in Cellular Neuroscience

Astrocyte Processes Label for Filamentous Actin and Reorient Early Within the Optic Nerve Head in a Rat Glaucoma Model

(2014) S. Tehrani et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

Astrogliosis

(2014) Michael V. Sofroniew   Cold Spring Harbor Perspectives in Biology

Reversible reactivity by optic nerve astrocytes

(2013) Daniel Sun et al.   GLIA

Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma

(2012) Gareth R. Howell et al.   JOURNAL OF CLINICAL INVESTIGATION

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Minocycline Suppresses Activation of Nuclear Factor of Activated T Cells 1 (NFAT1) in Human CD4+T Cells

(2011) Gregory L. Szeto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma

(2011) Gareth R. Howell et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural Remodeling of Astrocytes in the Injured CNS

(2011) Daniel Sun et al.   NEUROSCIENTIST

Neuroprotection by Minocycline Caused by Direct and Specific Scavenging of Peroxynitrite

(2010) Stefan Schildknecht et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early microglia activation in a mouse model of chronic glaucoma

(2010) Alejandra Bosco et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Structural Remodeling of Fibrous Astrocytes after Axonal Injury

(2010) D. Sun et al.   JOURNAL OF NEUROSCIENCE

Proteomic analysis of the anti-inflammatory action of minocycline

(2010) Christopher R. Dunston et al.   PROTEOMICS

Loss of Astrocytic Domain Organization in the Epileptic Brain

(2008) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE