Tollip, an early regulator of the acute inflammatory response in the substantia nigra

Anti-high mobility group box 1 antibody exerts neuroprotection in a rat model of Parkinson's disease

(2016) Tatsuya Sasaki et al.   EXPERIMENTAL NEUROLOGY

Preventing Overheating

(2016) Christina Begka et al.   INFLAMMATORY BOWEL DISEASES

Immunolocalization of Tom1 in relation to protein degradation systems in Alzheimer's disease

(2016) Kouki Makioka et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The Enemy within: Innate Surveillance-Mediated Cell Death, the Common Mechanism of Neurodegenerative Disease

(2016) Robert I. Richards et al.   Frontiers in Neuroscience

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

(2015) Latarsha J. Carithers et al.   BIOPRESERVATION AND BIOBANKING

The role of the nitric oxide pathway in brain injury and its treatment — From bench to bedside

(2015) P.S. Garry et al.   EXPERIMENTAL NEUROLOGY

Tollip is a critical mediator of cerebral ischaemia-reperfusion injury

(2015) Mingchang Li et al.   JOURNAL OF PATHOLOGY

Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease

(2015) Diana M. Norden et al.   NEUROPHARMACOLOGY

The human transcriptome across tissues and individuals

(2015) M. Mele et al.   SCIENCE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

(2015) Latarsha J. Carithers et al.   Biopreservation and Biobanking

Autophagic Clearance of PolyQ Proteins Mediated by Ubiquitin-Atg8 Adaptors of the Conserved CUET Protein Family

(2014) Kefeng Lu et al.   CELL

Toll-interacting Protein Modulates Colitis Susceptibility in Mice

(2014) Michel H. Maillard et al.   INFLAMMATORY BOWEL DISEASES

Macrophage Polarization in Bacterial Infections

(2014) M. Benoit et al.   JOURNAL OF IMMUNOLOGY

Biological role of Toll-like receptor-4 in the brain

(2014) Teresa Trotta et al.   JOURNAL OF NEUROIMMUNOLOGY

LRRK2 and neuroinflammation: partners in crime in Parkinson’s disease?

(2014) Isabella Russo et al.   Journal of Neuroinflammation

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Microglial priming in neurodegenerative disease

(2014) V. Hugh Perry et al.   Nature Reviews Neurology

p38α (MAPK14) critically regulates the immunological response and the production of specific cytokines and chemokines in astrocytes

(2014) U. Lo et al.   Scientific Reports

May the Evaluation of Nitrosative Stress Through Selective Increase of 3-Nitrotyrosine Proteins Other Than Nitroalbumin and Dominant Tyrosine-125/136 Nitrosylation of Serum α-Synuclein Serve for Diagnosis of Sporadic Parkinson's Disease?

(2013) Emilio Fernández et al.   ANTIOXIDANTS & REDOX SIGNALING

Ubiquitin Interacts with the Tollip C2 and CUE Domains and Inhibits Binding of Tollip to Phosphoinositides

(2013) Sharmistha Mitra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Adeno-Associated Virus-Based Intracellular Sensor of Pathological Nuclear Factor-κB Activation for Disease-Inducible Gene Transfer

(2013) Abdelwahed Chtarto et al.   PLoS One

Molecular Mechanisms Responsible for the Selective and Low-Grade Induction of Proinflammatory Mediators in Murine Macrophages by Lipopolysaccharide

(2012) U. Maitra et al.   JOURNAL OF IMMUNOLOGY

CD4+ Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson’s Disease

(2012) Jessica A. Hutter Saunders et al.   Journal of Neuroimmune Pharmacology

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

(2012) David H Cribbs et al.   Journal of Neuroinflammation

Contributions of central and systemic inflammation to the pathophysiology of Parkinson's disease

(2012) Louise M. Collins et al.   NEUROPHARMACOLOGY

Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease

(2011) Hui-Ming Gao et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9

(2011) D Dalkara et al.   GENE THERAPY

LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury

(2011) Keri B Vartanian et al.   Journal of Neuroinflammation

Tollip: a multitasking protein in innate immunity and protein trafficking

(2011) Daniel G.S. Capelluto   MICROBES AND INFECTION

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Protective role of the ubiquitin binding protein Tollip against the toxicity of polyglutamine-expansion proteins

(2011) Asami Oguro et al.   NEUROSCIENCE LETTERS

Neuroinflammation in Parkinson's disease

(2011) Etienne C. Hirsch et al.   PARKINSONISM & RELATED DISORDERS

Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease

(2011) Christopher B. Forsyth et al.   PLoS One

Characterization of a Recombinant Adeno-Associated Virus Type 2 Reference Standard Material

(2010) Martin Lock et al.   HUMAN GENE THERAPY

Inflammatory Neurodegeneration and Mechanisms of Microglial Killing of Neurons

(2010) Guy C. Brown et al.   MOLECULAR NEUROBIOLOGY

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

(2010) Taye H Hamza et al.   NATURE GENETICS

Low-Grade Endotoxemia Contributes to Chronic Inflammation in Hemodialysis Patients: Examination With a Novel Lipopolysaccharide Detection Method

(2010) Hiroyuki Terawaki et al.   THERAPEUTIC APHERESIS AND DIALYSIS

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

(2009) Etienne C Hirsch et al.   LANCET NEUROLOGY

Diversification of TOLLIP isoforms in mouse and man

(2009) Yu-Lan S. Lo et al.   MAMMALIAN GENOME

Endotoxin induces a delayed loss of TH-IR neurons in substantia nigra and motor behavioral deficits

(2008) Yuxin Liu et al.   NEUROTOXICOLOGY

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression

(2008) Hui-Ming Gao et al.   TRENDS IN IMMUNOLOGY