Neuropharmacologic Approaches to Restore the Brain’s Microenvironment

Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders

(2016) Yu Cai et al.   Autophagy

The intersection between growth factors, autophagy and ER stress: A new target to treat neurodegenerative diseases?

(2016) Paula Garcia-Huerta et al.   BRAIN RESEARCH

Delivery of Therapeutic Proteins via Extracellular Vesicles: Review and Potential Treatments for Parkinson’s Disease, Glioma, and Schwannoma

(2016) Justin Hall et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Inflammatory mechanisms of endometritis

(2015) E. M. Woodward et al.   EQUINE VETERINARY JOURNAL

Active immunization therapies for Parkinson's disease and multiple system atrophy

(2015) Achim Schneeberger et al.   MOVEMENT DISORDERS

Enabling nanomaterial, nanofabrication and cellular technologies for nanoneuromedicines

(2015) Surya K. Mallapragada et al.   Nanomedicine-Nanotechnology Biology and Medicine

Review: An update on clinical, genetic and pathological aspects of frontotemporal lobar degenerations

(2015) Tammaryn Lashley et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

TLR2 and TLR9 Synergistically Control Herpes Simplex Virus Infection in the Brain

(2014) L. N. Sorensen et al.   JOURNAL OF IMMUNOLOGY

Stem Cells Loaded With Multimechanistic Oncolytic Herpes Simplex Virus Variants for Brain Tumor Therapy

(2014) Matthias Duebgen et al.   JNCI-Journal of the National Cancer Institute

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

GDNF-Transfected Macrophages Produce Potent Neuroprotective Effects in Parkinson's Disease Mouse Model

(2014) Yuling Zhao et al.   PLoS One

The Multifunctional Anti-inflammatory Drugs Used in the Therapy of Alzheimer’s Disease

(2013) S. Shi et al.   CURRENT MEDICINAL CHEMISTRY

Mast cells, glia and neuroinflammation: partners in crime?

(2013) Stephen D. Skaper et al.   IMMUNOLOGY

The New Small-Molecule Mixed-Lineage Kinase 3 Inhibitor URMC-099 Is Neuroprotective and Anti-Inflammatory in Models of Human Immunodeficiency Virus-Associated Neurocognitive Disorders

(2013) D. F. Marker et al.   JOURNAL OF NEUROSCIENCE

Diffusion of Macromolecules in the Brain: Implications for Drug Delivery

(2013) Daniel J. Wolak et al.   MOLECULAR PHARMACEUTICS

Microglia: Scapegoat, Saboteur, or Something Else?

(2013) A. Aguzzi et al.   SCIENCE

Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity

(2013) Jessian L Munoz et al.   Molecular Therapy-Nucleic Acids

Innate immunity in the central nervous system

(2012) Richard M. Ransohoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Monocyte maturation, HIV susceptibility, and transmigration across the blood brain barrier are critical in HIV neuropathogenesis

(2012) Dionna W. Williams et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Exosome-mediated delivery of siRNA in vitro and in vivo

(2012) Samir El-Andaloussi et al.   Nature Protocols

Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood–brain barrier using focused ultrasound and microbubbles

(2012) Babak Baseri et al.   PHYSICS IN MEDICINE AND BIOLOGY

Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment

(2011) Jarek Harezlak et al.   AIDS

Brain Cell Reservoirs of Latent Virus in Presymptomatic HIV-Infected Individuals

(2011) Katherine A. Thompson et al.   AMERICAN JOURNAL OF PATHOLOGY

Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS

(2011) Shengbo Cao et al.   Journal of Neuroinflammation

Loss of Neuronal Integrity during Progressive HIV-1 Infection of Humanized Mice

(2011) P. K. Dash et al.   JOURNAL OF NEUROSCIENCE

Neurocognitive Effects of HIV, Hepatitis C, and Substance Use History

(2011) Kathryn N. Devlin et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease

(2010) Nicholas D. Dey et al.   BEHAVIOURAL BRAIN RESEARCH

Trafficking of immune cells in the central nervous system

(2010) Emma H. Wilson et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage-mediated GDNF Delivery Protects Against Dopaminergic Neurodegeneration: A Therapeutic Strategy for Parkinson's Disease

(2010) KC Biju et al.   MOLECULAR THERAPY

Macrophage delivery of therapeutic nanozymes in a murine model of Parkinson’s disease

(2010) Anna M Brynskikh et al.   Nanomedicine

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

c-Jun NH2-TERMINAL KINASE REGULATES LIPOPOLYSACCHARIDE-INDUCED PULMONARY MONONUCLEAR CELL RECRUITMENT VIA CCL2

(2009) Scott K. Young et al.   EXPERIMENTAL LUNG RESEARCH

Neuroprotective Activities of CEP-1347 in Models of NeuroAIDS

(2009) D. Eggert et al.   JOURNAL OF IMMUNOLOGY

Macrophage Delivery of Nanoformulated Antiretroviral Drug to the Brain in a Murine Model of NeuroAIDS

(2009) H. Dou et al.   JOURNAL OF IMMUNOLOGY

NanoART, neuroAIDS and CNS drug delivery

(2009) Ari Nowacek et al.   Nanomedicine

Neurodegenerative disorders and nanoformulated drug development

(2009) Ari Nowacek et al.   Nanomedicine

Inflammation, microglia, and alzheimer's disease

(2009) Brent Cameron et al.   NEUROBIOLOGY OF DISEASE

Approaches to transport therapeutic drugs across the blood–brain barrier to treat brain diseases

(2009) Reinhard Gabathuler   NEUROBIOLOGY OF DISEASE

Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors

(2009) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

Cellular Reservoirs of HIV-1 and their Role in Viral Persistence

(2008) Aikaterini Alexaki et al.   CURRENT HIV RESEARCH

HIV-1-infected and/or immune-activated macrophages regulate astrocyte CXCL8 production through IL-1β and TNF-α: Involvement of mitogen-activated protein kinases and protein kinase R

(2008) Jialin C. Zheng et al.   JOURNAL OF NEUROIMMUNOLOGY

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice

(2008) Barbara L. Apostol et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Absolute requirement of GDNF for adult catecholaminergic neuron survival

(2008) Alberto Pascual et al.   NATURE NEUROSCIENCE

Can the immune system be harnessed to repair the CNS?

(2008) Phillip G. Popovich et al.   NATURE REVIEWS NEUROSCIENCE