Article
Biochemistry & Molecular Biology
Maryam Doostan, Hassan Maleki, Mahtab Doostan, Kamyar Khoshnevisan, Reza Faridi-Majidi, Elham Arkan
Summary: In this study, antibacterial nanofibrous mats loaded with erythromycin-chitosan nanoparticles were fabricated for infected wound dressing applications. The mats showed high encapsulation efficiency and smooth homogenous morphology, indicating their potential for use in infected wound dressing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Nanoscience & Nanotechnology
Brian Derby, Jinxin Yang, Pei He
Summary: Continuous conducting lines with a width of 5-20 μm have been successfully printed using Ag nanoparticle ink and drop-on-demand (DOD) electrohydrodynamic (EHD) inkjet printing. The stability of the printed lines is affected by the contact angle and the spacing between drops. The upper and lower bounds of the drop spacing for stable line formation are consistent with existing models. After printing and sintering, the conductivity of the printed tracks is about 15%-20% of bulk Ag, indicating a porosity of about 60%.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Pharmacology & Pharmacy
Esra Altun, Esra Yuca, Nazmi Ekren, Deepak M. Kalaskar, Denisa Ficai, Georgiana Dolete, Anton Ficai, Oguzhan Gunduz
Summary: This study utilized electrohydrodynamic 3D printing to fabricate BC/PCL patches loaded with various antibiotics, showing efficient drug loading, encapsulation, and extended release profiles. The produced patches exhibited excellent antimicrobial activity against both Gram-positive and Gram-negative strains, potentially aiding in the treatment of chronic infectious lesions.
Article
Ophthalmology
Shizuka Koh, Ryota Inoue, Naoyuki Maeda, Yoshinori Oie, Vishal Jhanji, Atsuya Miki, Kohji Nishida
Summary: This study found that wearing spherical corneal rigid gas-permeable contact lenses can lead to refractive changes in the posterior corneal surface in keratoconus patients and these changes are correlated with corneal biomechanics. The spherical, regular astigmatism, and asymmetry components were significantly reduced when wearing corneal GPs.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Engineering, Manufacturing
M. Aravind, Santhosh Chidangil, Sajan D. George
Summary: In this study, we demonstrate the feasibility of using capillary rise in microchannels embedded in contact lenses to keep them moisturized. The technique is simple and can be easily combined with existing manufacturing techniques.
ADDITIVE MANUFACTURING
(2022)
Article
Ophthalmology
Sabrina Mukhtar, Sarah Atta, Asad Durrani, Chandrashan Perera, Regis Kowalski, Vishal Jhanji
Summary: The degree of microbiological agreement between corneal scrapings and contact lens cultures in cases of contact lens-associated keratitis was investigated. The results showed that although there was disagreement in the microbiological yield, contact lens cultures were useful in managing patients and achieved similar outcomes to corneal scrapings.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Green & Sustainable Science & Technology
Kirsi Immonen, Sini Metsa-Kortelainen, Juha Nurmio, Amelie Tribot, Tuomas Turpeinen, Atte Mikkelson, Tomi Kalpio, Otto-Ville Kaukoniemi, Heli Kangas
Summary: 3D printing enables sustainable product innovations through novel design, reduced use of materials, and local manufacturing. This research studied the properties of a cellulose-based composite in injection molding and 3D printing processes. The results showed that the polymer matrix could be directly recyclable for both processes without degradation, while microcellulose was more sensitive to thermal stress. The mechanical and thermal properties of the cellulose-based composites remained close to initial levels throughout the multiple processing cycles.
Article
Chemistry, Multidisciplinary
Qianni Wu, Cheng Yang, Wan Chen, Kexin Chen, Hui-jiuan Chen, Fanmao Liu, Dong Liu, Haotian Lin, Xi Xie, Weirong Chen
Summary: A wireless-powered electrical bandage contact lens (EBCL) is developed to accelerate corneal wound healing and vision recovery through generating a localized external electric field. The electrical stimulation promotes cell migration and alignment, and controls cell division, proliferation, and migration.
Article
Pharmacology & Pharmacy
Tatsuaki Tagami, Eiichi Goto, Risako Kida, Kiyomi Hirose, Takehiro Noda, Tetsuya Ozeki
Summary: 3D printing technology has great potential in the pharmaceutical field. This study presents the fabrication of ophthalmologic patches using a 3D printer, which enables controlled drug release and personalized dosages.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Ophthalmology
Motohiro Itoi, Motozumi Itoi
Summary: Prolonged wear of soft contact lenses with low oxygen permeability can lead to corneal deformation in patients, highlighting the importance of careful observation of changes in both the anterior and posterior corneal surface by healthcare providers.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Automation & Control Systems
Jun Chen, Ting Wu, Libing Zhang, Haijun Song, Chengli Tang, Xiangying Yan
Summary: To improve the resolution of printed patterns fabricated with PEDOT:PSS organic conductive polymer printing solutions, a high-voltage electrostatic focusing lens-based electrohydrodynamic (EHD) jet printing method was proposed and analyzed. Flexible conductive patterns were printed on photographic paper using the PEDOT:PSS mixed solution as the printing solution. The effects of working voltage, motion platform velocity, and injection pump flow rate on pattern width were analyzed. The high-voltage electrostatic focusing lens-based EHD jet printing method demonstrated higher resolution compared to the traditional method, offering a new approach for achieving high-resolution pattern printing of PEDOT:PSS organic conductive polymer printing solutions.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2023)
Review
Ophthalmology
Richard M. Pearson
Summary: The aim of this review is to commemorate the 75th anniversary of the introduction of the original corneal contact lens of Tuohy in 1948. By consulting American documents in the public domain, the author provides a comprehensive biography of Kevin M Tuohy, inventor of the corneal contact lens, and addresses historical inaccuracies regarding its design and dimensions. The clinical success of the Tuohy lens and its simpler fitting procedure compared to scleral lenses have had a significant impact on the development of contact lens practice.
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Chemistry, Multidisciplinary
Rong Sun, Shuting Ma, Xi Chen, Yaxin Deng, Jingxin Gou, Tian Yin, Haibing He, Yanjiao Wang, Xing Tang, Yu Zhang
Summary: The frequent use of glucocorticoid eye drops can cause side effects and reduce patient compliance. To address this issue, a responsive dexamethasone contact lens with sustained release properties was developed by introducing a ROS-responsive monomer and high-oxygen-permeability materials. In vivo experiments demonstrated the lens's efficacy in reducing inflammation, suppressing neovascularization, and providing a safe and effective treatment for ocular surface diseases.
JOURNAL OF CONTROLLED RELEASE
(2023)
Article
Instruments & Instrumentation
Dazhi Wang, Yikang Li, Xin Hu, Liangkun Lu, Pengfei Xu, Xiangji Chen, Chang Liu, Lunxiang Wang, Ben Liu, Liujia Suo, Yan Cui, Junsheng Liang
Summary: Inspired by nature, a high-aspect-ratio piezoelectric hair-like sensor was developed using electrohydrodynamic jet printing technology. The sensor exhibited high sensitivity and a wide detection range, capable of detecting airflow velocities as low as 0.01 m/s. It also demonstrated a rapid detection response with a response time of 70 ms. This sensor has potential applications in biosensing and airflow monitoring.
SMART MATERIALS AND STRUCTURES
(2023)
Review
Ophthalmology
Young Hyun Kim, Thien C. Nguyen, Meng C. Lin, Cheng-Chun J. Peng, Clayton J. Radke
Summary: Hyperosmotic tears can stimulate the cornea and cause dry eye symptoms, but the use of soft contact lenses can protect the cornea from these effects. Current measurement methods for tear osmolarity during lens wear do not accurately reflect the osmolarity of the tear film that covers the cornea. Dry eye patients can benefit from contact lenses with low salt diffusivity to reduce their tear osmolarity to normal levels.
PROGRESS IN RETINAL AND EYE RESEARCH
(2022)
Article
Nanoscience & Nanotechnology
Chunchen Zhang, Yudong Li, Yejun Hu, Yu Peng, Zeeshan Ahmad, Jing-Song Li, Ming-Wei Chang
ACS APPLIED MATERIALS & INTERFACES
(2019)
Article
Food Science & Technology
Li-Fang Zhu, Xing Chen, Zijing Wu, Guangkun Wang, Zeeshan Ahmad, Ming-Wei Chang
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2020)
Article
Engineering, Biomedical
Li-Fang Zhu, Xing Chen, Zeeshan Ahmad, Yu Peng, Ming-Wei Chang
Article
Pharmacology & Pharmacy
Kazem Nazari, Prina Mehta, Muhammad Sohail Arshad, Shahabuddin Ahmed, Eleftherios G. Andriotis, Neenu Singh, Omar Qutachi, Ming-Wei Chang, Dimitrios G. Fatouros, Zeeshan Ahmad
Article
Engineering, Chemical
Zhi-Cheng Yao, Chunchen Zhang, Zeeshan Ahmad, Yu Peng, Ming-Wei Chang
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2020)
Review
Pharmacology & Pharmacy
Prina Mehta, Manoochehr Rasekh, Mohammed Patel, Ekhoerose Onaiwu, Kazem Nazari, I. Kucuk, Philippe B. Wilson, Muhammad Sohail Arshad, Zeeshan Ahmad, Ming-Wei Chang
Summary: Advancements in technology and material development have led to significant breakthroughs in fiber engineering in recent years. Traditional methods have limitations, but emerging techniques such as electrospinning, centrifugal spinning, and pressurized gyration are showing potential in applications like drug delivery and regenerative medicine.
ADVANCED DRUG DELIVERY REVIEWS
(2021)
Review
Chemistry, Analytical
Kirsty Muldoon, Yanhua Song, Zeeshan Ahmad, Xing Chen, Ming-Wei Chang
Summary: Three dimensional printing, also known as additive manufacturing, is a rapidly growing process that has applications in various sectors such as electronics, biomedical, pharmaceutical, and tissue engineering. Micro and nano scale printing allows for precise control over design, material, and chemical properties, resulting in high surface area to volume ratios and altered mechanical and physical properties of the products. This review discusses the applications of micro/nano printing technologies such as lithography, inkjet, and electrohydrodynamic printing in the biomedical and electronic fields. The limitations of current micro/nano printing methods, particularly in achieving controlled structures at the required tiny micro and nano scales, are also examined.
Article
Chemistry, Multidisciplinary
Amirsadra Ahmadi, Moses Sokunbi, Trisha Patel, Ming-Wei Chang, Zeeshan Ahmad, Neenu Singh
Summary: This study statistically analyzed the factors influencing the biocompatibility and toxicity of Mesoporous Silica Nanoparticles (MSNs) in the past five years, including physicochemical properties, experimental conditions, and other experimental parameters.
Article
Chemistry, Analytical
Kirsty Muldoon, Zeeshan Ahmad, Yu-Chuan Su, Fan-Gang Tseng, Xing Chen, James A. D. McLaughlin, Ming-Wei Chang
Summary: Personalised drug delivery systems with real-time imaging have the potential to revolutionize diagnostic and therapeutic applications. In this study, a 3D-printed drug delivery matrix with real-time imaging capability was developed, offering promising applications in drug delivery systems, medical imaging, and targeted therapy.
Article
Materials Science, Multidisciplinary
Renyuan Sun, Baolin Wang, Longfei Zhang, Yuna Lang, Ming-Wei Chang
Summary: In this study, a novel bendable helix conduit was fabricated using a combination of electrohydrodynamic printing and electrospinning. The conduit showed excellent flexibility, stability, and adsorption capacity, making it a promising option for clinical treatment of peripheral nerve injuries.
ACS MATERIALS LETTERS
(2022)
