3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons

Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges

(2016) Aiwu Cheng et al.   Cell Metabolism

Lifelong brain health is a lifelong challenge: From evolutionary principles to empirical evidence

(2015) Mark P. Mattson   AGEING RESEARCH REVIEWS

Ketone bodies mediate antiseizure effects through mitochondrial permeability transition

(2015) Do Young Kim et al.   ANNALS OF NEUROLOGY

Understanding the Cellular and Molecular Mechanisms of Physical Activity-Induced Health Benefits

(2015) P. Darrell Neufer et al.   Cell Metabolism

Sirtuin 3 Mediates Neuroprotection of Ketones against Ischemic Stroke

(2015) Junxiang Yin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Fasting: Molecular Mechanisms and Clinical Applications

(2014) Valter D. Longo et al.   Cell Metabolism

A High-Fat Diet and NAD + Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome

(2014) Morten Scheibye-Knudsen et al.   Cell Metabolism

�-Hydroxybutyrate Activates the NF-κB Signaling Pathway to Promote the Expression of Pro-Inflammatory Factors in Calf Hepatocytes

(2014) Xiaoxia Shi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Contribution of Ketone Bodies to Basal and Activity-Dependent Neuronal Oxidation in Vivo

(2014) Golam MI Chowdhury et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

An Atypical NF- B-Regulated Pathway Mediates Phorbol Ester-Dependent Heme Oxygenase-1 Gene Activation in Monocytes

(2014) S. Naidu et al.   JOURNAL OF IMMUNOLOGY

The collective therapeutic potential of cerebral ketone metabolism in traumatic brain injury

(2014) Mayumi L. Prins et al.   JOURNAL OF LIPID RESEARCH

Evidence that BDNF regulates heart rate by a mechanism involving increased brainstem parasympathetic neuron excitability

(2014) Ruiqian Wan et al.   JOURNAL OF NEUROCHEMISTRY

Exercise, Energy Intake, Glucose Homeostasis, and the Brain

(2014) H. van Praag et al.   JOURNAL OF NEUROSCIENCE

Metabolic Stress Modulates Alzheimer’s β-Secretase Gene Transcription via SIRT1-PPARγ-PGC-1 in Neurons

(2013) Ruishan Wang et al.   Cell Metabolism

Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway

(2013) Christiane D. Wrann et al.   Cell Metabolism

BDNF and Exercise Enhance Neuronal DNA Repair by Stimulating CREB-Mediated Production of Apurinic/Apyrimidinic Endonuclease 1

(2013) Jenq-Lin Yang et al.   NEUROMOLECULAR MEDICINE

Bridging animal and human models of exercise-induced brain plasticity

(2013) Michelle W. Voss et al.   TRENDS IN COGNITIVE SCIENCES

BDNF mediates adaptive brain and body responses to energetic challenges

(2013) Krisztina Marosi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Ketone bodies as signaling metabolites

(2013) John C. Newman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Augmentation of Normal and Glutamate-Impaired Neuronal Respiratory Capacity by Exogenous Alternative Biofuels

(2013) Melissa D. Laird et al.   Translational Stroke Research

Energy Intake and Exercise as Determinants of Brain Health and Vulnerability to Injury and Disease

(2012) Mark P. Mattson   Cell Metabolism

Brain-derived neurotrophic factor-mediated effects on mitochondrial respiratory coupling and neuroprotection share the same molecular signalling pathways

(2012) Anthony Markham et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Ketone bodies in epilepsy

(2012) Melanie A. McNally et al.   JOURNAL OF NEUROCHEMISTRY

Dietary energy intake modifies brainstem autonomic dysfunction caused by mutant α-synuclein

(2012) Kathleen J. Griffioen et al.   NEUROBIOLOGY OF AGING

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease

(2012) Yoshihiro Kashiwaya et al.   NEUROBIOLOGY OF AGING

Long-term exercise treatment reduces oxidative stress in the hippocampus of aging rats

(2012) K. Marosi et al.   NEUROSCIENCE

Suppression of Oxidative Stress by  -Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

(2012) T. Shimazu et al.   SCIENCE

Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines

(2012) Aiwu Cheng et al.   Nature Communications

7,8-Dihydroxyflavone, a Small-Molecule TrkB Agonist, Reverses Memory Deficits and BACE1 Elevation in a Mouse Model of Alzheimer's Disease

(2011) Latha Devi et al.   NEUROPSYCHOPHARMACOLOGY

Low-Level Laser Therapy Activates NF-kB via Generation of Reactive Oxygen Species in Mouse Embryonic Fibroblasts

(2011) Aaron C-H. Chen et al.   PLoS One

Lack of promoter IV-driven BDNF transcription results in depression-like behavior

(2010) K. Sakata et al.   GENES BRAIN AND BEHAVIOR

Age and energy intake interact to modify cell stress pathways and stroke outcome

(2009) Thiruma V. Arumugam et al.   ANNALS OF NEUROLOGY

Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice

(2009) Alexis M. Stranahan et al.   HIPPOCAMPUS

Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity

(2009) Tobias B Dansen et al.   Nature Chemical Biology

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

Distribution of the monocarboxylate transporter MCT2 in human cerebral cortex: An immunohistochemical study

(2008) Oriana Chiry et al.   BRAIN RESEARCH

Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice

(2008) Catharine H. Duman et al.   BRAIN RESEARCH

The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

(2008) Marwan Maalouf et al.   BRAIN RESEARCH REVIEWS

Dietary restriction started after spinal cord injury improves functional recovery

(2008) Ward T. Plunet et al.   EXPERIMENTAL NEUROLOGY

Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats

(2008) Alexis M. Stranahan et al.   HIPPOCAMPUS

Fasting is neuroprotective following traumatic brain injury

(2008) Laurie M. Davis et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis

(2007) J.L. Trejo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE