MiR-449a regulates autophagy to inhibit silica-induced pulmonary fibrosis through targeting Bcl2

Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts

(2015) S Ghavami et al.   Cell Death & Disease

Lipid from Infective L. donovani Regulates Acute Myeloid Cell Growth via Mitochondria Dependent MAPK Pathway

(2015) Nabanita Chatterjee et al.   PLoS One

The Anti-fibrotic Effects and Mechanisms of MicroRNA-486-5p in Pulmonary Fibrosis

(2015) Xiaoming Ji et al.   Scientific Reports

Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells

(2014) Hua Zhu et al.   Autophagy

Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF

(2014) Monique Bernard et al.   Autophagy

Interleukin 17A inhibits autophagy through activation of PIK3CA to interrupt the GSK3B-mediated degradation of BCL2 in lung epithelial cells

(2013) Hong Liu et al.   Autophagy

MIR181Aregulates starvation- and rapamycin-induced autophagy through targeting ofATG5

(2013) Kumsal Ayse Tekirdag et al.   Autophagy

Tumor-suppressive microRNA-449a induces growth arrest and senescence by targeting E2F3 in human lung cancer cells

(2013) Xiao-Shuai Ren et al.   CANCER LETTERS

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

(2013) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

1-Methyl-4-Phenylpyridinium-Induced Cell Death via Autophagy Through a Bcl-2/Beclin 1 Complex-Dependent Pathway

(2013) Chutikorn Nopparat et al.   NEUROCHEMICAL RESEARCH

Silica induces NLRP3 inflammasome activation in human lung epithelial cells

(2013) Paul M Peeters et al.   Particle and Fibre Toxicology

miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1

(2012) Gozde Korkmaz et al.   Autophagy

MicroRNA-449a acts as a tumor suppressor in human bladder cancer through the regulation of pocket proteins

(2012) Hong Chen et al.   CANCER LETTERS

miRNA-130a Targets ATG2B and DICER1 to Inhibit Autophagy and Trigger Killing of Chronic Lymphocytic Leukemia Cells

(2012) V. Kovaleva et al.   CANCER RESEARCH

The Emerging Importance of Autophagy in Pulmonary Diseases

(2012) Kenji Mizumura et al.   CHEST

Autophagy Promotes Intracellular Degradation of Type I Collagen Induced by Transforming Growth Factor (TGF)-β1

(2012) Sung Il Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased expression of autophagic beclin 1 protein in idiopathic pulmonary fibrosis fibroblasts

(2012) Alberto Ricci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Fibroblast autophagy in fibrotic disorders

(2012) Domenico Del Principe et al.   JOURNAL OF PATHOLOGY

Silicosis

(2012) Chi Chiu Leung et al.   LANCET

Autophagy in Idiopathic Pulmonary Fibrosis

(2012) Avignat S. Patel et al.   PLoS One

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

MicroRNA-449 in cell fate determination

(2011) Muriel Lizé et al.   CELL CYCLE

microRNA-101 is a potent inhibitor of autophagy

(2011) Lisa B Frankel et al.   EMBO JOURNAL

Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF- 1-Dependent and -Independent Mechanisms

(2011) S. Mi et al.   JOURNAL OF IMMUNOLOGY

Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway

(2011) Brice Marcet et al.   NATURE CELL BIOLOGY

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

(2011) Patrick Brest et al.   NATURE GENETICS

Inhibition and Role of let-7d in Idiopathic Pulmonary Fibrosis

(2010) Kusum V. Pandit et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis

(2010) Feifan Zhou et al.   FEBS Journal

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lung function loss in relation to silica dust exposure in South African gold miners

(2010) R. I. Ehrlich et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death

(2009) Kyung-Jin Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-449a targets HDAC-1 and induces growth arrest in prostate cancer

(2009) E J Noonan et al.   ONCOGENE

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

ERK/BCL-2 Pathway in the Resistance of Pancreatic Cancer to Anoikis

(2008) Joseph M. Galante et al.   JOURNAL OF SURGICAL RESEARCH

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

A comparative study of grape seed extract and vitamin E effects on silica-induced pulmonary fibrosis in rats

(2008) Ali A. Hemmati et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS