CARD14 Signalling Ensures Cell Survival and Cancer Associated Gene Expression in Prostate Cancer Cells

Mucosa-Associated Lymphoid Tissue 1 Is an Oncogene Inducing Cell Proliferation, Invasion, and Tumor Growth via the Upregulation of NF-κB Activity in Human Prostate Carcinoma Cells

(2021) Ke-Hung Tsui et al.   Biomedicines

Altered replication stress response due to CARD14 mutations promotes recombination-induced revertant mosaicism

(2021) Toshinari Miyauchi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Targeting MALT1 for the treatment of diffuse large B-cell lymphoma

(2021) Madhav R. Seshadri et al.   LEUKEMIA & LYMPHOMA

Integrative Analysis of MALT1 as a Potential Therapeutic Target for Prostate Cancer and its Immunological Role in Pan-Cancer

(2021) Haotian Tan et al.   Frontiers in Molecular Biosciences

Pharmacological Inhibition of MALT1 Protease Leads to a Progressive IPEX-Like Pathology

(2020) Kea Martin et al.   Frontiers in Immunology

Defining the combinatorial space of PKC::CARD‐CC signal transduction nodes

(2020) Jens Staal et al.   FEBS Journal

The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

(2020) Boris Y. Shorning et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages

(2020) Nathalia Moraes de Vasconcelos et al.   Cell Reports

Long-Term MALT1 Inhibition in Adult Mice Without Severe Systemic Autoimmunity

(2020) Annelies Demeyer et al.   iScience

MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner

(2019) Annelies Demeyer et al.   Frontiers in Immunology

The role of JNK in prostate cancer progression and therapeutic strategies

(2019) Ruiyuan Xu et al.   BIOMEDICINE & PHARMACOTHERAPY

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

(2018) Daniel E. Johnson et al.   Nature Reviews Clinical Oncology

Glucose impairments and insulin resistance in prostate cancer: the role of obesity, nutrition and exercise

(2018) K. M. Di Sebastiano et al.   Obesity Reviews

Break-Induced Replication: The Where, The Why, and The How

(2018) J. Kramara et al.   TRENDS IN GENETICS

Inflammation and NF-κB Signaling in Prostate Cancer: Mechanisms and Clinical Implications

(2018) Jens Staal et al.   Cells

The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition

(2017) Maureen Bardet et al.   IMMUNOLOGY AND CELL BIOLOGY

Essential Role of CARD14 in Murine Experimental Psoriasis

(2017) Mayuri Tanaka et al.   JOURNAL OF IMMUNOLOGY

A pathology atlas of the human cancer transcriptome

(2017) Mathias Uhlen et al.   SCIENCE

Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF- B activation

(2016) A. Howes et al.   BIOCHEMICAL JOURNAL

Role of the CARMA1/BCL10/MALT1 complex in lymphoid malignancies

(2016) Mélanie Juilland et al.   CURRENT OPINION IN HEMATOLOGY

The paracaspase MALT1 mediates CARD14‐induced signaling in keratinocytes

(2016) Inna S Afonina et al.   EMBO REPORTS

Targeting MALT1 Proteolytic Activity in Immunity, Inflammation and Disease: Good or Bad?

(2016) Annelies Demeyer et al.   TRENDS IN MOLECULAR MEDICINE

MALT1 - a universal soldier: multiple strategies to ensure NF-κB activation and target gene expression

(2015) Inna S. Afonina et al.   FEBS Journal

The CBM Complex Underwrites NF- B Activation to Promote HER2-Associated Tumor Malignancy

(2015) D. Pan et al.   MOLECULAR CANCER RESEARCH

MALT1 is required for EGFR-induced NF-κB activation and contributes to EGFR-driven lung cancer progression

(2015) D Pan et al.   ONCOGENE

The Three CARMA Sisters: So Different, So Similar: A Portrait of the Three CARMA Proteins and Their Involvement in Human Disorders

(2013) Ivan Scudiero et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Cycles of Ubiquitination and Deubiquitination Critically Regulate Growth Factor-Mediated Activation of Akt Signaling

(2013) W.-L. Yang et al.   Science Signaling

CARMA3 overexpression accelerates cell proliferation and inhibits paclitaxel-induced apoptosis through NF-κB regulation in breast cancer cells

(2013) Tingting Zhao et al.   TUMOR BIOLOGY

PSORS2 Is Due to Mutations in CARD14

(2012) Catherine T. Jordan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Rare and Common Variants in CARD14, Encoding an Epidermal Regulator of NF-kappaB, in Psoriasis

(2012) Catherine T. Jordan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Overexpression of CARMA3 in Non-Small-Cell Lung Cancer Is Linked for Tumor Progression

(2012) Zixuan Li et al.   PLoS One

Genetic factors regulating inflammation and DNA methylation associated with prostate cancer

(2012) M Ianni et al.   PROSTATE CANCER AND PROSTATIC DISEASES

T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1

(2011) Jens Staal et al.   EMBO JOURNAL

Most Random Gene Expression Signatures Are Significantly Associated with Breast Cancer Outcome

(2011) David Venet et al.   PLoS Computational Biology

CXCL12/SDF‐1α Activates NF‐κB and Promotes Oral Cancer Invasion through the Carma3/Bcl10/Malt1 Complex

(2010) Aasia O Rehman et al.   International Journal of Oral Science

T cell antigen receptor stimulation induces MALT1 paracaspase–mediated cleavage of the NF-κB inhibitor A20

(2008) Beatrice Coornaert et al.   NATURE IMMUNOLOGY