Pharmacological Inhibition of MALT1 Protease Leads to a Progressive IPEX-Like Pathology
出版年份 2020 全文链接
标题
Pharmacological Inhibition of MALT1 Protease Leads to a Progressive IPEX-Like Pathology
作者
关键词
-
出版物
Frontiers in Immunology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-04-30
DOI
10.3389/fimmu.2020.00745
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Novel MALT1 Mutation Linked to Immunodeficiency, Immune Dysregulation, and an Abnormal T Cell Receptor Repertoire
- (2019) Shirly Frizinsky et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Malt1 Protease Is Critical in Maintaining Function of Regulatory T Cells and May Be a Therapeutic Target for Antitumor Immunity
- (2019) Liqing Cheng et al. JOURNAL OF IMMUNOLOGY
- Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy
- (2019) Mauro Di Pilato et al. NATURE
- Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells
- (2019) Marc Rosenbaum et al. Nature Communications
- MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner
- (2019) Annelies Demeyer et al. Frontiers in Immunology
- Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell–Mediated Autoimmunity
- (2019) Kea Martin et al. JOURNAL OF IMMUNOLOGY
- Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1 protease
- (2019) Tianbao Lu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Treatment of DSS-induced colitis with mucosal-associated lymphoid tissue lymphoma translocation 1 inhibitor MI-2 is associated with restoration of gut immune function and the microbiota.
- (2018) Kyung Won Lee et al. INFECTION AND IMMUNITY
- Holding All the CARDs: How MALT1 Controls CARMA/CARD-Dependent Signaling
- (2018) Mélanie Juilland et al. Frontiers in Immunology
- The CBM-opathies—A Rapidly Expanding Spectrum of Human Inborn Errors of Immunity Caused by Mutations in the CARD11-BCL10-MALT1 Complex
- (2018) Henry Y. Lu et al. Frontiers in Immunology
- The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition
- (2017) Maureen Bardet et al. IMMUNOLOGY AND CELL BIOLOGY
- Selective MALT1 paracaspase inhibition does not block TNF-α production downstream of TLR4 in myeloid cells
- (2017) Adeline Unterreiner et al. IMMUNOLOGY LETTERS
- Deficiency in Mucosa-associated Lymphoid Tissue Lymphoma Translocation 1
- (2017) Fabienne Charbit-Henrion et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Successful clinical treatment and functional immunological normalization of human MALT1 deficiency following hematopoietic stem cell transplantation
- (2016) Jacob Rozmus et al. CLINICAL IMMUNOLOGY
- Targeting MALT1 Proteolytic Activity in Immunity, Inflammation and Disease: Good or Bad?
- (2016) Annelies Demeyer et al. TRENDS IN MOLECULAR MEDICINE
- MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-κB and NLRP3 inflammasome activation
- (2016) Wen Liu et al. Oncotarget
- MALT1 is an intrinsic regulator of regulatory T cells
- (2015) A Brüstle et al. CELL DEATH AND DIFFERENTIATION
- MALT1 is not alone after all: identification of novel paracaspases
- (2015) Paco Hulpiau et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Combined Immunodeficiency Due to MALT1 Mutations, Treated by Hematopoietic Cell Transplantation
- (2015) Divya Punwani et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Deficiency of MALT1 Paracaspase Activity Results in Unbalanced Regulatory and Effector T and B Cell Responses Leading to Multiorgan Inflammation
- (2015) Frédéric Bornancin et al. JOURNAL OF IMMUNOLOGY
- MALT1 Protease Activity Is Required for Innate and Adaptive Immune Responses
- (2015) Jong W. Yu et al. PLoS One
- Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity
- (2014) Maike Jaworski et al. EMBO JOURNAL
- Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis
- (2014) Conor Mc Guire et al. Journal of Neuroinflammation
- Uncoupling Malt1 Threshold Function from Paracaspase Activity Results in Destructive Autoimmune Inflammation
- (2014) Andreas Gewies et al. Cell Reports
- Combined immunodeficiency associated with homozygous MALT1 mutations
- (2013) Margaret L. McKinnon et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Paracaspase MALT1 Deficiency Protects Mice from Autoimmune-Mediated Demyelination
- (2013) C. Mc Guire et al. JOURNAL OF IMMUNOLOGY
- MALT1 Small Molecule Inhibitors Specifically Suppress ABC-DLBCL In Vitro and In Vivo
- (2012) Lorena Fontan et al. CANCER CELL
- Pharmacologic Inhibition of MALT1 Protease by Phenothiazines as a Therapeutic Approach for the Treatment of Aggressive ABC-DLBCL
- (2012) Daniel Nagel et al. CANCER CELL
- Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans
- (2012) Ineke den Braber et al. IMMUNITY
- From MALT lymphoma to the CBM signalosome
- (2011) Shaun Rosebeck et al. CELL CYCLE
- Inhibition of MALT1 protease activity is selectively toxic for activated B cell–like diffuse large B cell lymphoma cells
- (2009) Uta Ferch et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma
- (2009) S. Hailfinger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- T cell antigen receptor stimulation induces MALT1 paracaspase–mediated cleavage of the NF-κB inhibitor A20
- (2008) Beatrice Coornaert et al. NATURE IMMUNOLOGY
- The proteolytic activity of the paracaspase MALT1 is key in T cell activation
- (2008) Fabien Rebeaud et al. NATURE IMMUNOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started