The Impact of Tobacco Cigarettes, Vaping Products and Tobacco Heating Products on Oxidative Stress

Modeling Cardiovascular Risks of E-Cigarettes With Human-Induced Pluripotent Stem Cell–Derived Endothelial Cells

(2019) Won Hee Lee et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Chronic intermittent electronic cigarette exposure induces cardiac dysfunction and atherosclerosis in apolipoprotein-E knockout mice

(2019) Jorge Espinoza-Derout et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Customizable E-cigarette Resistance Influences Toxicological Outcomes: Lung Degeneration, Inflammation, and Oxidative Stress-Induced in a Rat Model

(2019) Silvia Cirillo et al.   TOXICOLOGICAL SCIENCES

Short-term e-cigarette vapour exposure causes vascular oxidative stress and dysfunction: evidence for a close connection to brain damage and a key role of the phagocytic NADPH oxidase (NOX-2)

(2019) Marin Kuntic et al.   EUROPEAN HEART JOURNAL

Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice

(2019) Moon-shong Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomarkers of Exposure and Effect in the Lungs of Smokers, Nonsmokers, and Electronic Cigarette Users

(2019) Min-Ae Song et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

A review of the impacts of tobacco heating system on indoor air quality versus conventional pollution sources

(2018) Violeta Kaunelienė et al.   CHEMOSPHERE

Electronic Cigarette Smoking Increases Arterial Stiffness and Oxidative Stress to a Lesser Extent Than a Single Conventional Cigarette

(2018) Ignatios Ikonomidis et al.   CIRCULATION

Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis

(2018) Kentaro Takahashi et al.   EUROPEAN RESPIRATORY JOURNAL

Electronic cigarette use in youths: a position statement of the Forum of International Respiratory Societies

(2018) Thomas W. Ferkol et al.   EUROPEAN RESPIRATORY JOURNAL

Assessment of mitochondrial function following short- and long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product and reference cigarettes

(2018) Dominika Malinska et al.   FOOD AND CHEMICAL TOXICOLOGY

Aldehyde levels in e-cigarette aerosol: Findings from a replication study and from use of a new-generation device

(2018) Konstantinos E. Farsalinos et al.   FOOD AND CHEMICAL TOXICOLOGY

Chemical analysis and in vitro toxicological evaluation of aerosol from a novel tobacco vapor product: A comparison with cigarette smoke

(2018) Yasunori Takahashi et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Oxidative stress, aging, and diseases

(2018) Ilaria Liguori et al.   Clinical Interventions in Aging

Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort

(2018) Rosalia Emma et al.   PLoS One

Differential Effects of E-Cigarette on Microvascular Endothelial Function, Arterial Stiffness and Oxidative Stress: A Randomized Crossover Trial

(2018) Martin Chaumont et al.   Scientific Reports

A novel hybrid tobacco product that delivers a tobacco flavour note with vapour aerosol (Part 2): In vitro biological assessment and comparison with different tobacco-heating products

(2017) Damien Breheny et al.   FOOD AND CHEMICAL TOXICOLOGY

Oxidative Stress and Cardiovascular Risk: Obesity, Diabetes, Smoking, and Pollution

(2017) Bernd Niemann et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The pathophysiological role of mitochondrial oxidative stress in lung diseases

(2017) Xiaojing Liu et al.   Journal of Translational Medicine

Comparative assessment of HPHC yields in the Tobacco Heating System THS2.2 and commercial cigarettes

(2017) G. Jaccard et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Evaluation of Oxidative Stress and Antioxidant Status in Chronic Obstructive Pulmonary Disease

(2017) S. Singh et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Mitochondrial alterations during oxidative stress in chronic obstructive pulmonary disease

(2017) Ying Jiang et al.   International Journal of Chronic Obstructive Pulmonary Disease

Electronic cigarettes: an aid in smoking cessation, or a new health hazard?

(2017) Konstantinos Farsalinos   Therapeutic Advances in Respiratory Disease

Electronic cigarette aerosols suppress cellular antioxidant defenses and induce significant oxidative DNA damage

(2017) Vengatesh Ganapathy et al.   PLoS One

E-cigarettes induce toxicological effects that can raise the cancer risk

(2017) Donatella Canistro et al.   Scientific Reports

Airway Exposure to E-Cigarette Vapors Impairs Autophagy and Induces Aggresome Formation

(2016) Prashanth Chandramani Shivalingappa et al.   ANTIOXIDANTS & REDOX SIGNALING

Effects of cigarette smoking on cardiovascular-related protein profiles in two community-based cohort studies

(2016) Biying Huang et al.   ATHEROSCLEROSIS

Acute Impact of Tobacco vs Electronic Cigarette Smoking on Oxidative Stress and Vascular Function

(2016) Roberto Carnevale et al.   CHEST

Cigarette smoke but not electronic cigarette aerosol activates a stress response in human coronary artery endothelial cells in culture

(2016) Jack E. Teasdale et al.   DRUG AND ALCOHOL DEPENDENCE

Evaluation of the Tobacco Heating System 2.2. Part 2: Chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol

(2016) Jean-Pierre Schaller et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Molecular Impact of Electronic Cigarette Aerosol Exposure in Human Bronchial Epithelium

(2016) Elizabeth Moses et al.   TOXICOLOGICAL SCIENCES

E-Cigarette Aerosol Exposure Induces Reactive Oxygen Species, DNA Damage, and Cell Death in Vascular Endothelial Cells

(2016) Chastain Anderson et al.   TOXICOLOGICAL SCIENCES

E-cigarette aerosols induce lower oxidative stress in vitro when compared to tobacco smoke

(2016) Mark Taylor et al.   TOXICOLOGY MECHANISMS AND METHODS

Smoking-promoted oxidative DNA damage response is highly correlated to lung carcinogenesis

(2016) Chao Cao et al.   Oncotarget

Heme oxygenase-1 nuclear translocation regulates bortezomib-induced cytotoxicity and mediates genomic instability in myeloma cells

(2016) Daniele Tibullo et al.   Oncotarget

The non-canonical functions of the heme oxygenases

(2016) Luca Vanella et al.   Oncotarget

E-cigarette aerosols induce lower oxidative stress in vitro when compared to tobacco smoke

(2016) Mark Taylor et al.   TOXICOLOGY MECHANISMS AND METHODS

Analysis of mitochondrial DNA alteration in new phenotype ACOS

(2016) G. E. Carpagnano et al.   BMC Pulmonary Medicine

The Expression of NOX4 in Smooth Muscles of Small Airway Correlates with the Disease Severity of COPD

(2016) Xianyan Liu et al.   Biomed Research International

POINT: Does the Risk of Electronic Cigarettes Exceed Potential Benefits? Yes

(2015) Mark V. Avdalovic et al.   CHEST

COUNTERPOINT: Does the Risk of Electronic Cigarettes Exceed Potential Benefits? No

(2015) Holly R. Middlekauff   CHEST

Targeting oxidant-dependent mechanisms for the treatment of COPD and its comorbidities

(2015) Ivan Bernardo et al.   PHARMACOLOGY & THERAPEUTICS

Nitric oxide synthase in innate and adaptive immunity: an update

(2015) Christian Bogdan   TRENDS IN IMMUNOLOGY

The role of oxidative stress, antioxidants and vascular inflammation in cardiovascular disease (a review)

(2015) Hawa N. Siti et al.   VASCULAR PHARMACOLOGY

Evaluation of E-Cigarette Liquid Vapor and Mainstream Cigarette Smoke after Direct Exposure of Primary Human Bronchial Epithelial Cells

(2015) Stefanie Scheffler et al.   International Journal of Environmental Research and Public Health

Exposure to Electronic Cigarettes Impairs Pulmonary Anti-Bacterial and Anti-Viral Defenses in a Mouse Model

(2015) Thomas E. Sussan et al.   PLoS One

Vapors Produced by Electronic Cigarettes and E-Juices with Flavorings Induce Toxicity, Oxidative Stress, and Inflammatory Response in Lung Epithelial Cells and in Mouse Lung

(2015) Chad A. Lerner et al.   PLoS One

A critique of a World Health Organization-commissioned report and associated paper on electronic cigarettes

(2014) Ann McNeill et al.   ADDICTION

Electronic Cigarettes. A Position Statement of the Forum of International Respiratory Societies

(2014) Dean E. Schraufnagel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Endothelin-1 Induces a Glycolytic Switch in Pulmonary Arterial Endothelial Cells via the Mitochondrial Translocation of Endothelial Nitric Oxide Synthase

(2014) Xutong Sun et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Oxidation contributes to low glutathione in the airways of children with cystic fibrosis

(2014) A. J. Kettle et al.   EUROPEAN RESPIRATORY JOURNAL

Redox balance in Cystic Fibrosis

(2014) Assem G. Ziady et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Predictors for the development of progressive severity in new-onset adult asthma

(2014) Guus A. Westerhof et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Particulate metals and organic compounds from electronic and tobacco-containing cigarettes: comparison of emission rates and secondhand exposure

(2014) Arian Saffari et al.   Environmental Science-Processes & Impacts

Oxidative stress and free radicals in COPD – implications and relevance for treatment

(2014) Wolfgang Domej et al.   International Journal of Chronic Obstructive Pulmonary Disease

Tobacco harm reduction: The need for new products that can compete with cigarettes

(2013) Karl Olov Fagerström et al.   ADDICTIVE BEHAVIORS

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

Lung cancer biomarkers for the assessment of modified risk tobacco products: an oxidative stress perspective

(2013) Frazer J. Lowe et al.   BIOMARKERS

Local and systemic neutrophilic inflammation in patients with lung cancer and chronic obstructive pulmonary disease

(2013) Neringa Vaguliene et al.   BMC IMMUNOLOGY

Pathophysiology of tobacco smoke exposure: Recent insights from comparative and redox proteomics

(2013) Graziano Colombo et al.   MASS SPECTROMETRY REVIEWS

Molecular mechanisms of reactive oxygen species-related pulmonary inflammation and asthma

(2013) Li Zuo et al.   MOLECULAR IMMUNOLOGY

The biology behind the atherothrombotic effects of cigarette smoke

(2013) Adam Csordas et al.   Nature Reviews Cardiology

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Cigarette smoking and inflammation revisited

(2013) Oren Rom et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Levels of selected carcinogens and toxicants in vapour from electronic cigarettes

(2013) Maciej Lukasz Goniewicz et al.   TOBACCO CONTROL

Coffee enhances the expression of chaperones and antioxidant proteins in rats with nonalcoholic fatty liver disease

(2013) Federico Salomone et al.   Translational Research

Should electronic cigarettes be as freely available as tobacco? Yes

(2013) J.-F. Etter   BMJ-British Medical Journal

Should electronic cigarettes be as freely available as tobacco cigarettes? No

(2013) S. Chapman   BMJ-British Medical Journal

Abnormal Lung Aging in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

(2012) Rosa Faner et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Identification of possible cigarette smoke constituents responsible for muscle catabolism

(2012) Oren Rom et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Stephen S Lim et al.   LANCET

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

Cigarette Smoking and Inflammation

(2011) J. Lee et al.   JOURNAL OF DENTAL RESEARCH

Chronic cigarette smoking causes hypertension, increased oxidative stress, impaired NO bioavailability, endothelial dysfunction, and cardiac remodeling in mice

(2010) M. A. Hassan Talukder et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Oxidative stress and accelerated vascular aging: implications for cigarette smoking

(2009) Anna Csiszar   Frontiers in Bioscience-Landmark

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Oxidative stress in the pathogenesis of diffuse lung diseases: A review

(2009) E. Bargagli et al.   RESPIRATORY MEDICINE

Tobacco Smoke: Involvement of Reactive Oxygen Species and Stable Free Radicals in Mechanisms of Oxidative Damage, Carcinogenesis and Synergistic Effects with Other Respirable Particles

(2009) Athanasios Valavanidis et al.   International Journal of Environmental Research and Public Health

Beneficial effects of rutin and l-arginine coadministration in a rat model of liver ischemia-reperfusion injury

(2008) Rosaria Acquaviva et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Effects of Aminoguanidine, an Inhibitor of Inducible Nitric Oxide Synthase, on Nitric Oxide Production and Its Metabolites in Healthy Control Subjects, Healthy Smokers, and COPD Patients

(2008) Caterina Brindicci et al.   CHEST

Cigarette smoking is associated with a greater risk of incident asthma in allergic rhinitis

(2008) Riccardo Polosa et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Biochemical Markers as a Response Guide for Steroid Therapy in Asthma

(2008) Amina Hamed Al Obaidi et al.   JOURNAL OF ASTHMA

Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies

(2008) Ulrich Förstermann   Nature clinical practice. Cardiovascular medicine

Nonequilibrium thermodynamics of thiol/disulfide redox systems: A perspective on redox systems biology

(2007) Melissa Kemp et al.   FREE RADICAL BIOLOGY AND MEDICINE