INPP4B inhibits glioma cell proliferation and immune escape via inhibition of the PI3K/AKT signaling pathway

Orphan nuclear receptor TLX promotes immunosuppression via its transcriptional activation of PD-L1 in glioma

(2021) Jiayi Zhou et al.   Journal for ImmunoTherapy of Cancer

Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma

(2021) Toshiro Hara et al.   CANCER CELL

The relationship between expression of PD-L1 and HIF-1α in glioma cells under hypoxia

(2021) Xing-chen Ding et al.   Journal of Hematology & Oncology

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

(2021) David N Louis et al.   NEURO-ONCOLOGY

Diagnostic, therapeutic, and prognostic implications of the 2021 World Health Organization classification of tumors of the central nervous system

(2021) Simon Gritsch et al.   CANCER

Inhibitory Effect of Hesperidin on the Expression of Programmed Death Ligand (PD-L1) in Breast Cancer

(2020) Prachya Kongtawelert et al.   MOLECULES

Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes

(2020) Zhuo Chen et al.   JOURNAL OF CONTROLLED RELEASE

The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer

(2020) Hui Liu et al.   Cancer Discovery

The Prognostic and Therapeutic Value of PD-L1 in Glioma

(2019) Ruo Qiao Chen et al.   Frontiers in Pharmacology

Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates

(2019) Zhuo Chen et al.   Nanomedicine

Challenges and potential of PD-1/PD-L1 checkpoint blockade immunotherapy for glioblastoma

(2019) Xin Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

INPP4B inhibits cell proliferation, invasion and chemoresistance in human hepatocellular carcinoma

(2019) Wendong Tang et al.   OncoTargets and Therapy

Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma

(2019) Dieter Henrik Heiland et al.   Nature Communications

PTEN Alterations as a Potential Mechanism for Tumor Cell Escape from PD-1/PD-L1 Inhibition

(2019) Cretella et al.   Cancers

PD-L1/PD-1 Axis in Glioblastoma Multiforme

(2019) Jakub Litak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanisms Controlling PD-L1 Expression in Cancer

(2019) Jong-Ho Cha et al.   MOLECULAR CELL

Astrocyte-derived CCL20 reinforces HIF-1-mediated hypoxic responses in glioblastoma by stimulating the CCR6-NF-κB signaling pathway

(2018) Peng Jin et al.   ONCOGENE

PD-1/PD-L1 immune checkpoint: Potential target for cancer therapy

(2018) Fatemeh K. Dermani et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Human glioblastoma arises from subventricular zone cells with low-level driver mutations

(2018) Joo Ho Lee et al.   NATURE

The IFN-γ/PD-L1 axis between T cells and tumor microenvironment: hints for glioma anti-PD-1/PD-L1 therapy

(2018) Jiawen Qian et al.   Journal of Neuroinflammation

INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC

(2017) Darien E. Reed et al.   MOLECULAR CANCER RESEARCH

Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma

(2017) Wilson X Mai et al.   NATURE MEDICINE

A blockade of PD-L1 produced antitumor and antimetastatic effects in an orthotopic mouse pancreatic cancer model via the PI3K/AkT/MTOR signaling pathway

(2017) Lei Zhao et al.   OncoTargets and Therapy

INPP4B is an oncogenic regulator in human colon cancer

(2015) S T Guo et al.   ONCOGENE

Astrocytes promote glioma invasion via the gap junction protein connexin43

(2015) W C Sin et al.   ONCOGENE

INPP4B Is a PtdIns(3,4,5)P3 Phosphatase That Can Act as a Tumor Suppressor

(2015) S. Kofuji et al.   Cancer Discovery

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy

(2015) W. Peng et al.   Cancer Discovery

In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes

(2015) C. Li Chew et al.   Cancer Discovery

PD-L1 Expression in Triple-Negative Breast Cancer

(2014) E. A. Mittendorf et al.   Cancer Immunology Research

Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

(2010) C. G. Fedele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA